Selective and efficient inhibition of the alternative pathway of complement by a mAb that recognizes C3b/iC3b

Molecular Immunology

Volumn 43, Issue 7, 2006, Pages 1010-1019

  DiLillo, David J ^a   Pawluczkowycz, Andrew W ^a   Peng, Wu ^b   Kennedy, Adam D ^a   Beum, Paul V ^a   Lindorfer, Margaret A ^a   Taylor, Ronald P ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b Elusys Therapeutics Inc   (United States)

Author keywords

Alternative pathway; Antibodies; Complement; Human

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; AMINO ACID; COMPLEMENT COMPONENT C3B; COMPLEMENT FACTOR H; EPITOPE; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G1 ANTIBODY; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 3E7; MONOCLONAL ANTIBODY H17; SEPHAROSE; UNCLASSIFIED DRUG; ZYMOSAN;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; HUMAN; HUMAN CELL; KINETICS; NONHUMAN; OPSONIZATION; PRIORITY JOURNAL; RABBIT; T LYMPHOCYTE;

ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; COMPLEMENT C3B; COMPLEMENT FACTOR B; COMPLEMENT FACTOR H; COMPLEMENT PATHWAY, ALTERNATIVE; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G;

ORYCTOLAGUS CUNICULUS;

EID: 29144459115     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2005.05.003     Document Type: Article

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