Curcumin induces G0/G1 arrest and apoptosis in hormone independent prostate cancer DU-145 cells by down regulating Notch signaling

Biomedicine and Pharmacotherapy

Volumn 84, Issue , 2016, Pages 177-184

  Sha, Jian ^a   Li, Junsheng ^a   Wang, Wei ^a   Pan, Liang ^a   Cheng, Jie ^a   Li, Li ^a   Zhao, Hong ^a   Lin, Wenyao ^a  

^a Shanghai Xuhui District Central Hospital   (China)

Author keywords

Curcumin; DU 145; Notch signaling; Prostate cancer

Indexed keywords

CASPASE 3; CASPASE 9; CURCUMIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; JAGGED1; NOTCH1 RECEPTOR; PROCASPASE 3; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT; NOTCH1 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG TARGETING; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; MALE; MTT ASSAY; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL CYCLE CHECKPOINT; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; PROSTATIC NEOPLASMS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; G1 PHASE; HUMANS; MALE; PROSTATIC NEOPLASMS; RECEPTOR, NOTCH1; RESTING PHASE, CELL CYCLE; SIGNAL TRANSDUCTION;

EID: 84988375011     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.09.037     Document Type: Article

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