-
1
-
-
84961226869
-
Epidemiology and natural history of nonalcoholic fatty liver disease
-
Y.Fazel, A.B.Koenig, M.Sayiner, et al. Epidemiology and natural history of nonalcoholic fatty liver disease. Metabolism. 2016;65:1017–1025.
-
(2016)
Metabolism
, vol.65
, pp. 1017-1025
-
-
Fazel, Y.1
Koenig, A.B.2
Sayiner, M.3
-
2
-
-
84961226571
-
Non-alcoholic fatty liver disease and liver transplantation
-
R.S.Khan, P.N.Newsome Non-alcoholic fatty liver disease and liver transplantation. Metabolism. 2016;65:1208–1223.
-
(2016)
Metabolism
, vol.65
, pp. 1208-1223
-
-
Khan, R.S.1
Newsome, P.N.2
-
3
-
-
61349140201
-
Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines
-
S.A.Polyzos, J.Kountouras, C.Zavos. Nonalcoholic fatty liver disease:the pathogenetic roles of insulin resistance and adipocytokines. Curr Mol Med. 2009;72:299–314.
-
(2009)
Curr Mol Med
, vol.72
, pp. 299-314
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
-
4
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
D.E.Kleiner, E.M.Brunt, M.Van Natta, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41:1313–1321.
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
-
5
-
-
84930788424
-
Nonalcoholic fatty liver disease: a systematic review
-
M.E.Rinella. Nonalcoholic fatty liver disease:a systematic review. JAMA. 2015;313:2263–2273.• An updated systematic review for NAFLD.
-
(2015)
JAMA
, vol.313
, pp. 2263-2273
-
-
Rinella, M.E.1
-
6
-
-
84962765638
-
EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease
-
G.Marchesini, M.Roden, R.Vettor, et al. EASL-EASD-EASO clinical practice guidelines for the management of non-alcoholic fatty liver disease. Diabetologia. 2016; 59:1121–1140.•• The most recent clinical practice guidelines for NAFLD management.
-
(2016)
Diabetologia
, vol.59
, pp. 1121-1140
-
-
Marchesini, G.1
Roden, M.2
Vettor, R.3
-
7
-
-
85027928562
-
NASH, from diagnosis to treatment: where do we stand?
-
S.A.Harrison. NASH, from diagnosis to treatment:where do we stand? Hepatology. 2015;62:1652–1655.
-
(2015)
Hepatology
, vol.62
, pp. 1652-1655
-
-
Harrison, S.A.1
-
8
-
-
84858842467
-
Nonalcoholic fatty liver disease: multimodal treatment options for a pathogenetically multiple-hit disease
-
S.A.Polyzos, J.Kountouras, C.Zavos, et al. Nonalcoholic fatty liver disease:multimodal treatment options for a pathogenetically multiple-hit disease. J Clin Gastroenterol. 2012;46:272–284.
-
(2012)
J Clin Gastroenterol
, vol.46
, pp. 272-284
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
-
9
-
-
84943411002
-
Ligands for the nuclear peroxisome proliferator-activated receptor gamma
-
S.Sauer. Ligands for the nuclear peroxisome proliferator-activated receptor gamma. Trends Pharmacol Sci. 2015;36:688–704.
-
(2015)
Trends Pharmacol Sci
, vol.36
, pp. 688-704
-
-
Sauer, S.1
-
10
-
-
84973518494
-
Adiponectin as a target for the treatment of nonalcoholic steatohepatitis with thiazolidinediones: a systematic review
-
S.A.Polyzos, C.S.Mantzoros. Adiponectin as a target for the treatment of nonalcoholic steatohepatitis with thiazolidinediones:a systematic review. Metabolism. 2016;65:1297–1306.
-
(2016)
Metabolism
, vol.65
, pp. 1297-1306
-
-
Polyzos, S.A.1
Mantzoros, C.S.2
-
11
-
-
0034804726
-
Pioglitazone: mechanism of action
-
U.Smith. Pioglitazone:mechanism of action. Int J Clin Pract Suppl. 2001;121:13–18.
-
(2001)
Int J Clin Pract Suppl
, vol.121
, pp. 13-18
-
-
Smith, U.1
-
12
-
-
84861543083
-
The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
-
N.Chalasani, Z.Younossi, J.E.Lavine, et al. The diagnosis and management of non-alcoholic fatty liver disease:practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology. 2012;55:2005–2023.
-
(2012)
Hepatology
, vol.55
, pp. 2005-2023
-
-
Chalasani, N.1
Younossi, Z.2
Lavine, J.E.3
-
13
-
-
84945185644
-
Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: a systematic review and network meta-analysis
-
S.Singh, R.Khera, A.M.Allen, et al. Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis:a systematic review and network meta-analysis. Hepatology. 2015;62:1417–1432.•• A network meta-analysis providing evidence for comparative effectiveness for medications investigated in NASH.
-
(2015)
Hepatology
, vol.62
, pp. 1417-1432
-
-
Singh, S.1
Khera, R.2
Allen, A.M.3
-
14
-
-
84862517200
-
Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials
-
G.Musso, M.Cassader, F.Rosina, et al. Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD):a systematic review and meta-analysis of randomised trials. Diabetologia. 2012;55:885–904.
-
(2012)
Diabetologia
, vol.55
, pp. 885-904
-
-
Musso, G.1
Cassader, M.2
Rosina, F.3
-
15
-
-
80055042241
-
The role of thiazolidinediones in non-alcoholic steatohepatitis – a systematic review and meta analysis
-
S.E.Mahady, A.C.Webster, S.Walker, et al. The role of thiazolidinediones in non-alcoholic steatohepatitis – a systematic review and meta analysis. J Hepatol. 2011;55:1383–1390.
-
(2011)
J Hepatol
, vol.55
, pp. 1383-1390
-
-
Mahady, S.E.1
Webster, A.C.2
Walker, S.3
-
16
-
-
84985993965
-
Long-term pioglitazone treatment for patients with nonalcoholic steatohepatitis and prediabetes or type 2 diabetes mellitus: a randomized, controlled trial
-
K.Cusi, B.Orsak, F.Bril, et al. Long-term pioglitazone treatment for patients with nonalcoholic steatohepatitis and prediabetes or type 2 diabetes mellitus:a randomized, controlled trial. Ann Intern Med. 2016. doi:10.7326/M15-1774.•• A well-conducted RCT with an open-label extension study on the long-term safety and efficacy of pioglitazone in NASH.
-
(2016)
Ann Intern Med
-
-
Cusi, K.1
Orsak, B.2
Bril, F.3
-
17
-
-
74349125502
-
Efficacy of insulin-sensitizing agents in nonalcoholic fatty liver disease
-
Z.Omer, S.Cetinkalp, M.Akyildiz, et al. Efficacy of insulin-sensitizing agents in nonalcoholic fatty liver disease. Eur J Gastroenterol Hepatol. 2010;22:18–23.
-
(2010)
Eur J Gastroenterol Hepatol
, vol.22
, pp. 18-23
-
-
Omer, Z.1
Cetinkalp, S.2
Akyildiz, M.3
-
18
-
-
80055031101
-
Rosiglitazone versus rosiglitazone and metformin versus rosiglitazone and losartan in the treatment of nonalcoholic steatohepatitis (NASH): a 12 month-randomized, prospective, open-label trial
-
D.Torres, F.Jones, J.Shaw, et al. Rosiglitazone versus rosiglitazone and metformin versus rosiglitazone and losartan in the treatment of nonalcoholic steatohepatitis (NASH):a 12 month-randomized, prospective, open-label trial. Hepatology. 2011;54:1631–1639.
-
(2011)
Hepatology
, vol.54
, pp. 1631-1639
-
-
Torres, D.1
Jones, F.2
Shaw, J.3
-
19
-
-
34548306770
-
The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis
-
G.Lutchman, A.Modi, D.E.Kleiner, et al. The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis. Hepatology. 2007;46:424–429.
-
(2007)
Hepatology
, vol.46
, pp. 424-429
-
-
Lutchman, G.1
Modi, A.2
Kleiner, D.E.3
-
20
-
-
67651093872
-
Thiazolidinediones for the treatment in NASH: sustained benefit after drug discontinuation?
-
C.K.Argo, J.C.Iezzoni, A.M.Al-Osaimi, et al. Thiazolidinediones for the treatment in NASH:sustained benefit after drug discontinuation? J Clin Gastroenterol. 2009;43:565–568.
-
(2009)
J Clin Gastroenterol
, vol.43
, pp. 565-568
-
-
Argo, C.K.1
Iezzoni, J.C.2
Al-Osaimi, A.M.3
-
21
-
-
77955285732
-
Rosiglitazone revisited: an updated meta-analysis of risk for myocardial infarction and cardiovascular mortality
-
S.E.Nissen, K.Wolski. Rosiglitazone revisited:an updated meta-analysis of risk for myocardial infarction and cardiovascular mortality. ArchInternMed. 2010;170:1191–1201.
-
(2010)
ArchInternMed
, vol.170
, pp. 1191-1201
-
-
Nissen, S.E.1
Wolski, K.2
-
22
-
-
79956217900
-
Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study
-
J.D.Lewis, A.Ferrara, T.Peng, et al. Risk of bladder cancer among diabetic patients treated with pioglitazone:interim report of a longitudinal cohort study. Diabetes Care. 2011;34:916–922.
-
(2011)
Diabetes Care
, vol.34
, pp. 916-922
-
-
Lewis, J.D.1
Ferrara, A.2
Peng, T.3
-
23
-
-
84941911821
-
Pharmacotherapy for nonalcoholic fatty liver disease
-
S.Gawrieh, N.Chalasani. Pharmacotherapy for nonalcoholic fatty liver disease. Semin Liver Dis. 2015;35:338–348.
-
(2015)
Semin Liver Dis
, vol.35
, pp. 338-348
-
-
Gawrieh, S.1
Chalasani, N.2
-
24
-
-
77951874018
-
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
-
A.J.Sanyal, N.Chalasani, K.V.Kowdley, et al. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med. 2010;362:1675–1685.•• A well-conducted RCT providing evidence for the efficacy of pioglitazone or vitamin E vs. placebo in adult NASH patients.
-
(2010)
N Engl J Med
, vol.362
, pp. 1675-1685
-
-
Sanyal, A.J.1
Chalasani, N.2
Kowdley, K.V.3
-
25
-
-
79955446251
-
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial
-
J.E.Lavine, J.B.Schwimmer, M.L.Van Natta, et al. Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents:the TONIC randomized controlled trial. JAMA. 2011;305:1659–1668.•• A well-conducted RCT providing evidence for the efficacy of metformin or vitamin E vs. placebo in children and adolescents with NASH.
-
(2011)
JAMA
, vol.305
, pp. 1659-1668
-
-
Lavine, J.E.1
Schwimmer, J.B.2
Van Natta, M.L.3
-
26
-
-
58149383852
-
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the selenium and vitamin E cancer prevention trial (SELECT)
-
S.M.Lippman, E.A.Klein, P.J.Goodman, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers:the selenium and vitamin E cancer prevention trial (SELECT). JAMA. 2009;301:39–51.
-
(2009)
JAMA
, vol.301
, pp. 39-51
-
-
Lippman, S.M.1
Klein, E.A.2
Goodman, P.J.3
-
27
-
-
19944427642
-
Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality
-
E.R.Miller3rd, R.Pastor-Barriuso, D.Dalal, et al. Meta-analysis:high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med. 2005;142:37–46.
-
(2005)
Ann Intern Med
, vol.142
, pp. 37-46
-
-
Miller, E.R.1
Pastor-Barriuso, R.2
Dalal, D.3
-
28
-
-
80055028155
-
Pentoxifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial
-
C.O.Zein, L.M.Yerian, P.Gogate, et al. Pentoxifylline improves nonalcoholic steatohepatitis:a randomized placebo-controlled trial. Hepatology. 2011;54:1610–1619.• A well-conducted RCT providing evidence for the efficacy of pentoxifylline in NASH patients.
-
(2011)
Hepatology
, vol.54
, pp. 1610-1619
-
-
Zein, C.O.1
Yerian, L.M.2
Gogate, P.3
-
29
-
-
84962053014
-
Pentoxifylline prevents nonalcoholic steatohepatitis-related liver pre-neoplasms by inhibiting hepatic inflammation and lipogenesis
-
Y.Shirakami, M.Shimizu, M.Kubota, et al. Pentoxifylline prevents nonalcoholic steatohepatitis-related liver pre-neoplasms by inhibiting hepatic inflammation and lipogenesis. Eur J Cancer Prev. 2016;25:206–215.
-
(2016)
Eur J Cancer Prev
, vol.25
, pp. 206-215
-
-
Shirakami, Y.1
Shimizu, M.2
Kubota, M.3
-
30
-
-
84990308922
-
Effects of pentoxifylline on non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled trial in Iran
-
N.Baniasadi, F.Salajegheh, A.Pardakhty, et al. Effects of pentoxifylline on non-alcoholic steatohepatitis:a randomized, double-blind, placebo-controlled trial in Iran. Hepat Mon. 2015;15:e32418.
-
(2015)
Hepat Mon
, vol.15
, pp. e32418
-
-
Baniasadi, N.1
Salajegheh, F.2
Pardakhty, A.3
-
31
-
-
84865499656
-
Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis
-
L.Adorini, M.Pruzanski, D.Shapiro. Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis. Drug Discov Today. 2012;17:988–997.
-
(2012)
Drug Discov Today
, vol.17
, pp. 988-997
-
-
Adorini, L.1
Pruzanski, M.2
Shapiro, D.3
-
32
-
-
77950613528
-
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats
-
S.Cipriani, A.Mencarelli, G.Palladino, et al. FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats. J Lipid Res. 2010;51:771–784.
-
(2010)
J Lipid Res
, vol.51
, pp. 771-784
-
-
Cipriani, S.1
Mencarelli, A.2
Palladino, G.3
-
33
-
-
56149126257
-
Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB: new insights into hepatic inflammation
-
M.Wagner, G.Zollner, M.Trauner. Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB:new insights into hepatic inflammation. Hepatology. 2008;48:1383–1386.
-
(2008)
Hepatology
, vol.48
, pp. 1383-1386
-
-
Wagner, M.1
Zollner, G.2
Trauner, M.3
-
34
-
-
84929266699
-
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
-
B.A.Neuschwander-Tetri, R.Loomba, A.J.Sanyal, et al. Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT):a multicentre, randomised, placebo-controlled trial. Lancet. 2015;385:956–965.•• A well-conducted RCT providing evidence for the efficacy of obeticholic acid in NASH patients.
-
(2015)
Lancet
, vol.385
, pp. 956-965
-
-
Neuschwander-Tetri, B.A.1
Loomba, R.2
Sanyal, A.J.3
-
35
-
-
84958078771
-
Effect of weight loss, diet, exercise, and bariatric surgery on nonalcoholic fatty liver disease
-
W.N.HannahJr., S.A.Harrison. Effect of weight loss, diet, exercise, and bariatric surgery on nonalcoholic fatty liver disease. Clin Liver Dis. 2016;20:339–350.
-
(2016)
Clin Liver Dis
, vol.20
, pp. 339-350
-
-
Hannah, W.N.1
Harrison, S.A.2
-
36
-
-
33646483917
-
A double-blind randomized placebo-controlled trial of orlistat for the treatment of nonalcoholic fatty liver disease
-
S.Zelber-Sagi, A.Kessler, E.Brazowsky, et al. A double-blind randomized placebo-controlled trial of orlistat for the treatment of nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2006;4:639–644.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 639-644
-
-
Zelber-Sagi, S.1
Kessler, A.2
Brazowsky, E.3
-
37
-
-
58949102847
-
Orlistat for overweight subjects with nonalcoholic steatohepatitis: a randomized, prospective trial
-
S.A.Harrison, W.Fecht, E.M.Brunt, et al. Orlistat for overweight subjects with nonalcoholic steatohepatitis:a randomized, prospective trial. Hepatology. 2009;49:80–86.
-
(2009)
Hepatology
, vol.49
, pp. 80-86
-
-
Harrison, S.A.1
Fecht, W.2
Brunt, E.M.3
-
38
-
-
0023125182
-
Is ursodeoxycholic acid an effective treatment for primary biliary cirrhosis?
-
R.Poupon, Y.Chretien, R.E.Poupon, et al. Is ursodeoxycholic acid an effective treatment for primary biliary cirrhosis? Lancet. 1987;1:834–836.
-
(1987)
Lancet
, vol.1
, pp. 834-836
-
-
Poupon, R.1
Chretien, Y.2
Poupon, R.E.3
-
39
-
-
84962393995
-
Efficacy and safety of ursodeoxycholic acid composite on fatigued patients with elevated liver function and/or fatty liver: a multi-centre, randomised, double-blinded, placebo-controlled trial
-
B.Oh, W.S.Choi, S.B.Park, et al. Efficacy and safety of ursodeoxycholic acid composite on fatigued patients with elevated liver function and/or fatty liver:a multi-centre, randomised, double-blinded, placebo-controlled trial. Int J Clin Pract. 2016;70:302–311.
-
(2016)
Int J Clin Pract
, vol.70
, pp. 302-311
-
-
Oh, B.1
Choi, W.S.2
Park, S.B.3
-
40
-
-
84884385162
-
The role of ursodeoxycholic acid in non-alcoholic steatohepatitis: a systematic review
-
Z.Xiang, Y.P.Chen, K.F.Ma, et al. The role of ursodeoxycholic acid in non-alcoholic steatohepatitis:a systematic review. BMC Gastroenterology. 2013;13:140.
-
(2013)
BMC Gastroenterology
, vol.13
, pp. 140
-
-
Xiang, Z.1
Chen, Y.P.2
Ma, K.F.3
-
41
-
-
84941600819
-
Nonalcoholic fatty liver disease and statins
-
K.Tziomalos, V.G.Athyros, P.Paschos, et al. Nonalcoholic fatty liver disease and statins. Metabolism. 2015;64:1215–1223.
-
(2015)
Metabolism
, vol.64
, pp. 1215-1223
-
-
Tziomalos, K.1
Athyros, V.G.2
Paschos, P.3
-
42
-
-
78649890465
-
Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) study: a post-hoc analysis
-
V.G.Athyros, K.Tziomalos, T.D.Gossios, et al. Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) study:a post-hoc analysis. Lancet. 2010;376:1916–1922.•• A well-conducted study providing evidence for the long-term efficacy and safety of statins in patients with abnormal liver function tests.
-
(2010)
Lancet
, vol.376
, pp. 1916-1922
-
-
Athyros, V.G.1
Tziomalos, K.2
Gossios, T.D.3
-
43
-
-
84858703583
-
Omega-3 supplementation and non-alcoholic fatty liver disease: a systematic review and meta-analysis
-
H.M.Parker, N.A.Johnson, C.A.Burdon, et al. Omega-3 supplementation and non-alcoholic fatty liver disease:a systematic review and meta-analysis. J Hepatol. 2012;56:944–951.
-
(2012)
J Hepatol
, vol.56
, pp. 944-951
-
-
Parker, H.M.1
Johnson, N.A.2
Burdon, C.A.3
-
46
-
-
84876725499
-
Treatment of nonalcoholic steatohepatitis with probiotics. A proof-of-concept study
-
V.W.Wong, G.L.Won, A.M.Chim, et al. Treatment of nonalcoholic steatohepatitis with probiotics. A proof-of-concept study. Ann Hepatol. 2013;12:256–262.
-
(2013)
Ann Hepatol
, vol.12
, pp. 256-262
-
-
Wong, V.W.1
Won, G.L.2
Chim, A.M.3
-
47
-
-
84962396651
-
Efficacy of probiotics in nonalcoholic fatty liver disease in adult and children: a meta-analysis of randomized controlled trials
-
X.Gao, Y.Zhu, Y.Wen, et al. Efficacy of probiotics in nonalcoholic fatty liver disease in adult and children:a meta-analysis of randomized controlled trials. Hepatol Res. 2016. doi:10.1111/hepr.12671.
-
(2016)
Hepatol Res
-
-
Gao, X.1
Zhu, Y.2
Wen, Y.3
-
48
-
-
25844497012
-
Nateglinide is useful for nonalcoholic steatohepatitis (NASH) patients with type 2 diabetes
-
Y.Morita, T.Ueno, N.Sasaki, et al. Nateglinide is useful for nonalcoholic steatohepatitis (NASH) patients with type 2 diabetes. Hepatogastroenterology. 2005;52:1338–1343.
-
(2005)
Hepatogastroenterology
, vol.52
, pp. 1338-1343
-
-
Morita, Y.1
Ueno, T.2
Sasaki, N.3
-
49
-
-
84888119563
-
Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial
-
M.J.Armstrong, D.Barton, P.Gaunt, et al. Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN):study protocol for a phase II multicentre, double-blinded, randomised, controlled trial. BMJ Open. 2013;3:e003995.
-
(2013)
BMJ Open
, vol.3
, pp. e003995
-
-
Armstrong, M.J.1
Barton, D.2
Gaunt, P.3
-
50
-
-
84957840942
-
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
-
M.J.Armstrong, P.Gaunt, G.P.Aithal, et al. Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN):a multicentre, double-blind, randomised, placebo-controlled phase 2 study. Lancet. 2016;387:679–690.•• A well-conducted RCT providing evidence for the efficacy of liraglutide in NASH patients.
-
(2016)
Lancet
, vol.387
, pp. 679-690
-
-
Armstrong, M.J.1
Gaunt, P.2
Aithal, G.P.3
-
51
-
-
84956914555
-
Incretin-based therapies for the treatment of non-alcoholic fatty liver disease: a systematic review and meta-analysis
-
L.J.Carbone, P.W.Angus, N.D.Yeomans. Incretin-based therapies for the treatment of non-alcoholic fatty liver disease:a systematic review and meta-analysis. J Gastroenterol Hepatol. 2016;31:23–31.
-
(2016)
J Gastroenterol Hepatol
, vol.31
, pp. 23-31
-
-
Carbone, L.J.1
Angus, P.W.2
Yeomans, N.D.3
-
52
-
-
33644803761
-
Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice
-
X.Ding, N.K.Saxena, S.Lin, et al. Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice. Hepatology. 2006;43:173–181.
-
(2006)
Hepatology
, vol.43
, pp. 173-181
-
-
Ding, X.1
Saxena, N.K.2
Lin, S.3
-
53
-
-
84855317103
-
Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet
-
J.E.Mells, P.P.Fu, S.Sharma, et al. Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet. Am J Physiol Gastrointest Liver Physiol. 2012;302:G225–35.
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
, pp. G225-G235
-
-
Mells, J.E.1
Fu, P.P.2
Sharma, S.3
-
54
-
-
84969801284
-
Sitagliptin versus placebo in the treatment of nonalcoholic fatty liver disease: a randomized controlled trial
-
J.Cui, L.Philo, P.Nguyen, et al. Sitagliptin versus placebo in the treatment of nonalcoholic fatty liver disease:a randomized controlled trial. J Hepatol. 2016;65:369–376.
-
(2016)
J Hepatol
, vol.65
, pp. 369-376
-
-
Cui, J.1
Philo, L.2
Nguyen, P.3
-
55
-
-
84925282923
-
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
-
B.Finan, B.Yang, N.Ottaway, et al. A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents. Nat Med. 2015;21:27–36.
-
(2015)
Nat Med
, vol.21
, pp. 27-36
-
-
Finan, B.1
Yang, B.2
Ottaway, N.3
-
56
-
-
84962619117
-
Effectiveness of ipragliflozin, a sodium-glucose co-transporter 2 inhibitor, as a second-line treatment for non-alcoholic fatty liver disease patients with type 2 diabetes mellitus who do not respond to incretin-based therapies including glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors
-
T.Ohki, A.Isogawa, N.Toda, et al. Effectiveness of ipragliflozin, a sodium-glucose co-transporter 2 inhibitor, as a second-line treatment for non-alcoholic fatty liver disease patients with type 2 diabetes mellitus who do not respond to incretin-based therapies including glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors. Clin Drug Investig. 2016;36:313–319.
-
(2016)
Clin Drug Investig
, vol.36
, pp. 313-319
-
-
Ohki, T.1
Isogawa, A.2
Toda, N.3
-
57
-
-
60849100836
-
The development of INT131 as a selective PPARgamma modulator: approach to a safer insulin sensitizer
-
L.S.Higgins, C.S.Mantzoros. The development of INT131 as a selective PPARgamma modulator:approach to a safer insulin sensitizer. PPAR Res. 2008;2008:936906.
-
(2008)
PPAR Res
, vol.2008
, pp. 936906
-
-
Higgins, L.S.1
Mantzoros, C.S.2
-
58
-
-
79955064893
-
Selective modulation of PPARgamma activity can lower plasma glucose without typical thiazolidinedione side-effects in patients with type 2 diabetes
-
F.L.Dunn, L.S.Higgins, J.Fredrickson, et al. Selective modulation of PPARgamma activity can lower plasma glucose without typical thiazolidinedione side-effects in patients with type 2 diabetes. J Diabetes Complications. 2011;25:151–158.
-
(2011)
J Diabetes Complications
, vol.25
, pp. 151-158
-
-
Dunn, F.L.1
Higgins, L.S.2
Fredrickson, J.3
-
59
-
-
84903550477
-
Can a selective PPARgamma modulator improve glycemic control in patients with type 2 diabetes with fewer side effects compared with pioglitazone?
-
A.M.DePaoli, L.S.Higgins, R.R.Henry, et al. Can a selective PPARgamma modulator improve glycemic control in patients with type 2 diabetes with fewer side effects compared with pioglitazone? Diabetes Care. 2014;37:1918–1923.
-
(2014)
Diabetes Care
, vol.37
, pp. 1918-1923
-
-
DePaoli, A.M.1
Higgins, L.S.2
Henry, R.R.3
-
60
-
-
84960140218
-
Elafibranor, an agonist of the peroxisome proliferator-activated receptor-alpha and -delta, induces resolution of nonalcoholic steatohepatitis without fibrosis worsening
-
e5
-
V.Ratziu, S.A.Harrison, S.Francque, et al. Elafibranor, an agonist of the peroxisome proliferator-activated receptor-alpha and -delta, induces resolution of nonalcoholic steatohepatitis without fibrosis worsening. Gastroenterology. 2016;150:1147–1159. e5.• A Phase 2b study providing evidence for the efficacy of elafibranor in NASH patients.
-
(2016)
Gastroenterology
, vol.150
, pp. 1147-1159
-
-
Ratziu, V.1
Harrison, S.A.2
Francque, S.3
-
61
-
-
84955125942
-
Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease
-
S.Heeboll, M.Kreuzfeldt, S.Hamilton-Dutoit, et al. Placebo-controlled, randomised clinical trial:high-dose resveratrol treatment for non-alcoholic fatty liver disease. Scand J Gastroenterol. 2016;51:456–464.
-
(2016)
Scand J Gastroenterol
, vol.51
, pp. 456-464
-
-
Heeboll, S.1
Kreuzfeldt, M.2
Hamilton-Dutoit, S.3
-
62
-
-
79954954319
-
Galectin-3 ablation protects mice from diet-induced NASH: a major scavenging role for galectin-3 in liver
-
C.Iacobini, S.Menini, C.Ricci, et al. Galectin-3 ablation protects mice from diet-induced NASH:a major scavenging role for galectin-3 in liver. J Hepatol. 2011;54:975–983.
-
(2011)
J Hepatol
, vol.54
, pp. 975-983
-
-
Iacobini, C.1
Menini, S.2
Ricci, C.3
-
63
-
-
84885155926
-
Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver disease
-
P.G.Traber, H.Chou, E.Zomer, et al. Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver disease. PLoS One. 2013;8:e75361.
-
(2013)
PLoS One
, vol.8
, pp. e75361
-
-
Traber, P.G.1
Chou, H.2
Zomer, E.3
-
64
-
-
84866950669
-
Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent
-
T.Aoyama, Y.H.Paik, S.Watanabe, et al. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis:GKT137831 as a novel potential therapeutic agent. Hepatology. 2012;56:2316–2327.
-
(2012)
Hepatology
, vol.56
, pp. 2316-2327
-
-
Aoyama, T.1
Paik, Y.H.2
Watanabe, S.3
-
65
-
-
84960110717
-
Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR phase 2b study design
-
S.Friedman, A.Sanyal, Z.Goodman, et al. Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis:CENTAUR phase 2b study design. Contemp Clin Trials. 2016;47:356–365.• A Phase 2b study providing evidence for the efficacy of cenicriviroc in NASH patients.
-
(2016)
Contemp Clin Trials
, vol.47
, pp. 356-365
-
-
Friedman, S.1
Sanyal, A.2
Goodman, Z.3
-
66
-
-
77956425361
-
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
-
V.Barry-Hamilton, R.Spangler, D.Marshall, et al. Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat Med. 2010;16:1009–1017.
-
(2010)
Nat Med
, vol.16
, pp. 1009-1017
-
-
Barry-Hamilton, V.1
Spangler, R.2
Marshall, D.3
-
67
-
-
77955519012
-
NPC1L1 inhibitor ezetimibe is a reliable therapeutic agent for non-obese patients with nonalcoholic fatty liver disease
-
M.Enjoji, K.Machida, M.Kohjima, et al. NPC1L1 inhibitor ezetimibe is a reliable therapeutic agent for non-obese patients with nonalcoholic fatty liver disease. Lipids Health Dis. 2010;9:29.
-
(2010)
Lipids Health Dis
, vol.9
, pp. 29
-
-
Enjoji, M.1
Machida, K.2
Kohjima, M.3
-
68
-
-
84957890102
-
Cardiovascular risk assessment in the treatment of nonalcoholic steatohepatitis: a secondary analysis of the MOZART trial
-
S.C.Lin, B.Ang, C.Hernandez, et al. Cardiovascular risk assessment in the treatment of nonalcoholic steatohepatitis:a secondary analysis of the MOZART trial. Therap Adv Gastroenterol. 2016;9:152–161.
-
(2016)
Therap Adv Gastroenterol
, vol.9
, pp. 152-161
-
-
Lin, S.C.1
Ang, B.2
Hernandez, C.3
-
69
-
-
84925339397
-
Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial)
-
R.Loomba, C.B.Sirlin, B.Ang, et al. Ezetimibe for the treatment of nonalcoholic steatohepatitis:assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial). Hepatology. 2015;61:1239–1250.
-
(2015)
Hepatology
, vol.61
, pp. 1239-1250
-
-
Loomba, R.1
Sirlin, C.B.2
Ang, B.3
-
70
-
-
78049421656
-
Fatty acid bile acid conjugate inhibits hepatic stearoyl coenzyme A desaturase and is non-atherogenic
-
A.Leikin-Frenkel, A.Gonen, A.Shaish, et al. Fatty acid bile acid conjugate inhibits hepatic stearoyl coenzyme A desaturase and is non-atherogenic. Arch Med Res. 2010;41:397–404.
-
(2010)
Arch Med Res
, vol.41
, pp. 397-404
-
-
Leikin-Frenkel, A.1
Gonen, A.2
Shaish, A.3
-
71
-
-
84918843434
-
The fatty acid-bile acid conjugate aramchol reduces liver fat content in patients with nonalcoholic fatty liver disease
-
e1
-
R.Safadi, F.M.Konikoff, M.Mahamid, et al. The fatty acid-bile acid conjugate aramchol reduces liver fat content in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2014;12:2085–2091. e1.
-
(2014)
Clin Gastroenterol Hepatol
, vol.12
, pp. 2085-2091
-
-
Safadi, R.1
Konikoff, F.M.2
Mahamid, M.3
-
73
-
-
84923636274
-
Leptin in health and disease: facts and expectations at its twentieth anniversary
-
S.A.Polyzos, C.S.Mantzoros. Leptin in health and disease:facts and expectations at its twentieth anniversary. Metabolism. 2015;64:5–12.
-
(2015)
Metabolism
, vol.64
, pp. 5-12
-
-
Polyzos, S.A.1
Mantzoros, C.S.2
-
74
-
-
84949319254
-
Circulating leptin in non-alcoholic fatty liver disease: a systematic review and meta-analysis
-
S.A.Polyzos, K.N.Aronis, J.Kountouras, et al. Circulating leptin in non-alcoholic fatty liver disease:a systematic review and meta-analysis. Diabetologia. 2015;59:30–43.
-
(2015)
Diabetologia
, vol.59
, pp. 30-43
-
-
Polyzos, S.A.1
Aronis, K.N.2
Kountouras, J.3
-
75
-
-
79951810722
-
Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis
-
S.A.Polyzos, K.A.Toulis, D.G.Goulis, et al. Serum total adiponectin in nonalcoholic fatty liver disease:a systematic review and meta-analysis. Metabolism. 2011;60:313–326.
-
(2011)
Metabolism
, vol.60
, pp. 313-326
-
-
Polyzos, S.A.1
Toulis, K.A.2
Goulis, D.G.3
-
76
-
-
84923597485
-
Leptin in nonalcoholic fatty liver disease: a narrative review
-
S.A.Polyzos, J.Kountouras, C.S.Mantzoros. Leptin in nonalcoholic fatty liver disease:a narrative review. Metabolism. 2015;64:60–78.
-
(2015)
Metabolism
, vol.64
, pp. 60-78
-
-
Polyzos, S.A.1
Kountouras, J.2
Mantzoros, C.S.3
-
77
-
-
85027945646
-
The potential adverse role of leptin resistance in nonalcoholic fatty liver disease: a hypothesis based on critical review of literature
-
S.A.Polyzos, J.Kountouras, C.Zavos, et al. The potential adverse role of leptin resistance in nonalcoholic fatty liver disease:a hypothesis based on critical review of literature. J Clin Gastroenterol. 2011;45:50–54.
-
(2011)
J Clin Gastroenterol
, vol.45
, pp. 50-54
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
-
78
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
A.Xu, Y.Wang, H.Keshaw, et al. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest. 2003;112:91–100.
-
(2003)
J Clin Invest
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
-
79
-
-
77952049390
-
The role of adiponectin in the pathogenesis and treatment of nonalcoholic fatty liver disease
-
S.A.Polyzos, J.Kountouras, C.Zavos, et al. The role of adiponectin in the pathogenesis and treatment of nonalcoholic fatty liver disease. Diabetes Obes Metab. 2010;12:365–383.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 365-383
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
-
80
-
-
77954351876
-
Adiponectin as a potential therapeutic agent for nonalcoholic steatohepatitis
-
S.A.Polyzos, J.Kountouras, C.Zavos. Adiponectin as a potential therapeutic agent for nonalcoholic steatohepatitis. Hepatol Res. 2010;40:446–447.
-
(2010)
Hepatol Res
, vol.40
, pp. 446-447
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
-
81
-
-
79951600378
-
Adiponectin in non-alcoholic fatty liver disease treatment: therapeutic perspectives and unresolved dilemmas
-
S.A.Polyzos, J.Kountouras, C.Zavos. Adiponectin in non-alcoholic fatty liver disease treatment:therapeutic perspectives and unresolved dilemmas. Int J Clin Pract. 2011;65:373–374.
-
(2011)
Int J Clin Pract
, vol.65
, pp. 373-374
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
-
82
-
-
84922708241
-
The pan-caspase inhibitor emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis
-
F.J.Barreyro, S.Holod, P.V.Finocchietto, et al. The pan-caspase inhibitor emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis. Liver Int. 2015;35:953–966.
-
(2015)
Liver Int
, vol.35
, pp. 953-966
-
-
Barreyro, F.J.1
Holod, S.2
Finocchietto, P.V.3
-
83
-
-
85049506142
-
Roles of FGFs as paracrine or endocrine signals in liver development, health, and disease
-
N.Itoh, Y.Nakayama, M.Konishi. Roles of FGFs as paracrine or endocrine signals in liver development, health, and disease. Front Cell Dev Biol. 2016;4:30.
-
(2016)
Front Cell Dev Biol
, vol.4
, pp. 30
-
-
Itoh, N.1
Nakayama, Y.2
Konishi, M.3
-
84
-
-
61649127208
-
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
-
J.Xu, D.J.Lloyd, C.Hale, et al. Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes. 2009;58:250–259.
-
(2009)
Diabetes
, vol.58
, pp. 250-259
-
-
Xu, J.1
Lloyd, D.J.2
Hale, C.3
-
85
-
-
84904755522
-
Metadoxine versus placebo for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial
-
K.T.Shenoy, L.K.Balakumaran, P.Mathew, et al. Metadoxine versus placebo for the treatment of non-alcoholic steatohepatitis:a randomized controlled trial. J Clin Exp Hepatol. 2014;4:94–100.
-
(2014)
J Clin Exp Hepatol
, vol.4
, pp. 94-100
-
-
Shenoy, K.T.1
Balakumaran, L.K.2
Mathew, P.3
-
86
-
-
77953165944
-
Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet
-
T.Wada, H.Kenmochi, Y.Miyashita, et al. Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet. Endocrinology. 2010;151:2040–2049.• An experimental study providing promising evidence for the therapeutic potential of spironolactone in NASH.
-
(2010)
Endocrinology
, vol.151
, pp. 2040-2049
-
-
Wada, T.1
Kenmochi, H.2
Miyashita, Y.3
-
87
-
-
84888875158
-
Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet
-
T.Wada, Y.Miyashita, M.Sasaki, et al. Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet. Am J Physiol Endocrinol Metab. 2013;305:E1415–25.
-
(2013)
Am J Physiol Endocrinol Metab
, vol.305
, pp. E1415-E1425
-
-
Wada, T.1
Miyashita, Y.2
Sasaki, M.3
-
88
-
-
83455201680
-
Effect of spironolactone and vitamin E on serum metabolic parameters and insulin resistance in patients with nonalcoholic fatty liver disease
-
S.A.Polyzos, J.Kountouras, E.Zafeiriadou, et al. Effect of spironolactone and vitamin E on serum metabolic parameters and insulin resistance in patients with nonalcoholic fatty liver disease. J Renin Angiotensin Aldosterone Syst. 2011;12:498–503.
-
(2011)
J Renin Angiotensin Aldosterone Syst
, vol.12
, pp. 498-503
-
-
Polyzos, S.A.1
Kountouras, J.2
Zafeiriadou, E.3
-
89
-
-
84955238943
-
Nonalcoholic fatty future disease
-
S.A.Polyzos, C.S.Mantzoros. Nonalcoholic fatty future disease. Metabolism. 2016;65:1007–1016.
-
(2016)
Metabolism
, vol.65
, pp. 1007-1016
-
-
Polyzos, S.A.1
Mantzoros, C.S.2
-
90
-
-
80053581540
-
Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States
-
M.R.Charlton, J.M.Burns, R.A.Pedersen, et al. Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States. Gastroenterology. 2011;141:1249–1253.
-
(2011)
Gastroenterology
, vol.141
, pp. 1249-1253
-
-
Charlton, M.R.1
Burns, J.M.2
Pedersen, R.A.3
-
91
-
-
84955213803
-
Association of nonalcoholic fatty liver disease (NAFLD) with hepatocellular carcinoma (HCC) in the United States from 2004 to 2009
-
Z.M.Younossi, M.Otgonsuren, L.Henry, et al. Association of nonalcoholic fatty liver disease (NAFLD) with hepatocellular carcinoma (HCC) in the United States from 2004 to 2009. Hepatology. 2015;62:1723–1730.
-
(2015)
Hepatology
, vol.62
, pp. 1723-1730
-
-
Younossi, Z.M.1
Otgonsuren, M.2
Henry, L.3
-
92
-
-
84892677099
-
Necessity for timely noninvasive diagnosis of nonalcoholic fatty liver disease
-
S.A.Polyzos, C.S.Mantzoros. Necessity for timely noninvasive diagnosis of nonalcoholic fatty liver disease. Metabolism. 2014;63:161–167.
-
(2014)
Metabolism
, vol.63
, pp. 161-167
-
-
Polyzos, S.A.1
Mantzoros, C.S.2
-
93
-
-
84957812743
-
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
-
E.Buzzetti, M.Pinzani, E.A.Tsochatzis. The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD). Metabolism. 2016;65(8):1038–1048.
-
(2016)
Metabolism
, vol.65
, Issue.8
, pp. 1038-1048
-
-
Buzzetti, E.1
Pinzani, M.2
Tsochatzis, E.A.3
-
94
-
-
65749118736
-
The multi-hit process and the antagonistic roles of tumor necrosis factor-alpha and adiponectin in nonalcoholic fatty liver disease
-
S.A.Polyzos, J.Kountouras, C.Zavos. The multi-hit process and the antagonistic roles of tumor necrosis factor-alpha and adiponectin in nonalcoholic fatty liver disease. Hippokratia. 2009;13:127.
-
(2009)
Hippokratia
, vol.13
, pp. 127
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
-
95
-
-
84939569154
-
An update on the validity of irisin assays and the link between irisin and hepatic metabolism
-
S.A.Polyzos, C.S.Mantzoros. An update on the validity of irisin assays and the link between irisin and hepatic metabolism. Metabolism. 2015;64:937–942.
-
(2015)
Metabolism
, vol.64
, pp. 937-942
-
-
Polyzos, S.A.1
Mantzoros, C.S.2
-
96
-
-
84907334403
-
Fructose, high-fructose corn syrup, sucrose, and nonalcoholic fatty liver disease or indexes of liver health: a systematic review and meta-analysis
-
M.Chung, J.Ma, K.Patel, et al. Fructose, high-fructose corn syrup, sucrose, and nonalcoholic fatty liver disease or indexes of liver health:a systematic review and meta-analysis. Am J Clin Nutr. 2014;100:833–849.
-
(2014)
Am J Clin Nutr
, vol.100
, pp. 833-849
-
-
Chung, M.1
Ma, J.2
Patel, K.3
-
97
-
-
84870908339
-
Helicobacter pylori infection in patients with nonalcoholic fatty liver disease
-
S.A.Polyzos, J.Kountouras, A.Papatheodorou, et al. Helicobacter pylori infection in patients with nonalcoholic fatty liver disease. Metabolism. 2013;62:121–126.
-
(2013)
Metabolism
, vol.62
, pp. 121-126
-
-
Polyzos, S.A.1
Kountouras, J.2
Papatheodorou, A.3
-
98
-
-
83455218004
-
The emerging role of endocrine disruptors in pathogenesis of insulin resistance: a concept implicating nonalcoholic fatty liver disease
-
S.A.Polyzos, J.Kountouras, G.Deretzi, et al. The emerging role of endocrine disruptors in pathogenesis of insulin resistance:a concept implicating nonalcoholic fatty liver disease. Curr Mol Med. 2012;12:68–82.
-
(2012)
Curr Mol Med
, vol.12
, pp. 68-82
-
-
Polyzos, S.A.1
Kountouras, J.2
Deretzi, G.3
-
99
-
-
78751575838
-
Insulin resistance and oxidative stress: two therapeutic targets in non-alcoholic steatohepatitis
-
C.S.Voican, G.Perlemuter. Insulin resistance and oxidative stress:two therapeutic targets in non-alcoholic steatohepatitis. J Hepatol. 2011;54:388–391.
-
(2011)
J Hepatol
, vol.54
, pp. 388-391
-
-
Voican, C.S.1
Perlemuter, G.2
-
100
-
-
78650969341
-
Effect of atorvastatin, vitamin E and C on nonalcoholic fatty liver disease: is the combination required?
-
B.M.Arendt, J.P.Allard. Effect of atorvastatin, vitamin E and C on nonalcoholic fatty liver disease:is the combination required? Am J Gastroenterol. 2011;106:78–80.•• A study providing evidence for combined treatment in NASH.
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 78-80
-
-
Arendt, B.M.1
Allard, J.P.2
|