메뉴 건너뛰기




Volumn 65, Issue 9, 2016, Pages 1297-1306

Adiponectin as a target for the treatment of nonalcoholic steatohepatitis with thiazolidinediones: A systematic review

Author keywords

Adiponectin; Nonalcoholic steatohepatitis; Pioglitazone; Rosiglitazone; Thiazolidinediones

Indexed keywords

ADIPONECTIN; CHOLESTEROL; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PENTOXIFYLLINE; PIOGLITAZONE; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPOQ PROTEIN, HUMAN;

EID: 84973518494     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2016.05.013     Document Type: Review
Times cited : (90)

References (53)
  • 2
    • 61349140201 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: The pathogenetic roles of insulin resistance and adipocytokines
    • SA Polyzos, J Kountouras, and C Zavos Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines Curr Mol Med 72 2009 299 314
    • (2009) Curr Mol Med , vol.72 , pp. 299-314
    • Polyzos, S.A.1    Kountouras, J.2    Zavos, C.3
  • 3
    • 84930788424 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A systematic review
    • ME Rinella Nonalcoholic fatty liver disease: a systematic review JAMA 313 2015 2263 2273
    • (2015) JAMA , vol.313 , pp. 2263-2273
    • Rinella, M.E.1
  • 4
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • N Chalasani, Z Younossi, JE Lavine, AM Diehl, EM Brunt, K Cusi, and et al. The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association Hepatology 55 2012 2005 2023
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3    Diehl, A.M.4    Brunt, E.M.5    Cusi, K.6
  • 6
    • 77952049390 scopus 로고    scopus 로고
    • The role of adiponectin in the pathogenesis and treatment of nonalcoholic fatty liver disease
    • SA Polyzos, J Kountouras, C Zavos, and E Tsiaousi The role of adiponectin in the pathogenesis and treatment of nonalcoholic fatty liver disease Diabetes Obes Metab 12 2010 365 383
    • (2010) Diabetes Obes Metab , vol.12 , pp. 365-383
    • Polyzos, S.A.1    Kountouras, J.2    Zavos, C.3    Tsiaousi, E.4
  • 7
    • 79951810722 scopus 로고    scopus 로고
    • Serum total adiponectin in nonalcoholic fatty liver disease: A systematic review and meta-analysis
    • SA Polyzos, KA Toulis, DG Goulis, C Zavos, and J Kountouras Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis Metabolism 60 2011 313 326
    • (2011) Metabolism , vol.60 , pp. 313-326
    • Polyzos, S.A.1    Toulis, K.A.2    Goulis, D.G.3    Zavos, C.4    Kountouras, J.5
  • 8
    • 77954351876 scopus 로고    scopus 로고
    • Adiponectin as a potential therapeutic agent for nonalcoholic steatohepatitis
    • SA Polyzos, J Kountouras, and C Zavos Adiponectin as a potential therapeutic agent for nonalcoholic steatohepatitis Hepatol Res 40 2010 446 447
    • (2010) Hepatol Res , vol.40 , pp. 446-447
    • Polyzos, S.A.1    Kountouras, J.2    Zavos, C.3
  • 9
    • 79951600378 scopus 로고    scopus 로고
    • Adiponectin in non-alcoholic fatty liver disease treatment: Therapeutic perspectives and unresolved dilemmas
    • SA Polyzos, J Kountouras, and C Zavos Adiponectin in non-alcoholic fatty liver disease treatment: therapeutic perspectives and unresolved dilemmas Int J Clin Pract 65 2011 373 374
    • (2011) Int J Clin Pract , vol.65 , pp. 373-374
    • Polyzos, S.A.1    Kountouras, J.2    Zavos, C.3
  • 10
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • A Xu, Y Wang, H Keshaw, LY Xu, KS Lam, and GJ Cooper The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice J Clin Invest 112 2003 91 100
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 11
    • 67649598622 scopus 로고    scopus 로고
    • Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization
    • J Fukushima, Y Kamada, H Matsumoto, Y Yoshida, H Ezaki, T Takemura, and et al. Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization Hepatol Res 39 2009 724 738
    • (2009) Hepatol Res , vol.39 , pp. 724-738
    • Fukushima, J.1    Kamada, Y.2    Matsumoto, H.3    Yoshida, Y.4    Ezaki, H.5    Takemura, T.6
  • 12
    • 77953806826 scopus 로고    scopus 로고
    • Adiponectin-it's all about the modifications
    • F Simpson, and JP Whitehead Adiponectin-it's all about the modifications Int J Biochem Cell Biol 42 2010 785 788
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 785-788
    • Simpson, F.1    Whitehead, J.P.2
  • 13
    • 84943411002 scopus 로고    scopus 로고
    • Ligands for the nuclear peroxisome proliferator-activated receptor gamma
    • S Sauer Ligands for the nuclear peroxisome proliferator-activated receptor gamma Trends Pharmacol Sci 36 2015 688 704
    • (2015) Trends Pharmacol Sci , vol.36 , pp. 688-704
    • Sauer, S.1
  • 14
    • 84858842467 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Multimodal treatment options for a pathogenetically multiple-hit disease
    • SA Polyzos, J Kountouras, C Zavos, and G Deretzi Nonalcoholic fatty liver disease: multimodal treatment options for a pathogenetically multiple-hit disease J Clin Gastroenterol 46 2012 272 284
    • (2012) J Clin Gastroenterol , vol.46 , pp. 272-284
    • Polyzos, S.A.1    Kountouras, J.2    Zavos, C.3    Deretzi, G.4
  • 15
    • 84945185644 scopus 로고    scopus 로고
    • Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta-analysis
    • S Singh, R Khera, AM Allen, MH Murad, and R Loomba Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: a systematic review and network meta-analysis Hepatology 62 2015 1417 1432
    • (2015) Hepatology , vol.62 , pp. 1417-1432
    • Singh, S.1    Khera, R.2    Allen, A.M.3    Murad, M.H.4    Loomba, R.5
  • 16
    • 84862517200 scopus 로고    scopus 로고
    • Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis of randomised trials
    • G Musso, M Cassader, F Rosina, and R Gambino Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials Diabetologia 55 2012 885 904
    • (2012) Diabetologia , vol.55 , pp. 885-904
    • Musso, G.1    Cassader, M.2    Rosina, F.3    Gambino, R.4
  • 17
    • 80055042241 scopus 로고    scopus 로고
    • The role of thiazolidinediones in non-alcoholic steatohepatitis - A systematic review and meta analysis
    • SE Mahady, AC Webster, S Walker, A Sanyal, and J George The role of thiazolidinediones in non-alcoholic steatohepatitis - a systematic review and meta analysis J Hepatol 55 2011 1383 1390
    • (2011) J Hepatol , vol.55 , pp. 1383-1390
    • Mahady, S.E.1    Webster, A.C.2    Walker, S.3    Sanyal, A.4    George, J.5
  • 18
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • D Moher, A Liberati, J Tetzlaff, and DG Altman Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Ann Intern Med 151 2009 264 269
    • (2009) Ann Intern Med , vol.151 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 19
    • 0034685429 scopus 로고    scopus 로고
    • Meta-analysis of observational studies in epidemiology: A proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group
    • DF Stroup, JA Berlin, SC Morton, I Olkin, GD Williamson, D Rennie, and et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group JAMA 283 2000 2008 2012
    • (2000) JAMA , vol.283 , pp. 2008-2012
    • Stroup, D.F.1    Berlin, J.A.2    Morton, S.C.3    Olkin, I.4    Williamson, G.D.5    Rennie, D.6
  • 20
    • 33746881442 scopus 로고    scopus 로고
    • Efficacy of rosiglitazone in treatment of nonalcoholic fatty liver disease and its relations with adiponectin
    • KQ Cui, XW Zhao, Y Zhang, XH Kang, J Meng, and XL Chen Efficacy of rosiglitazone in treatment of nonalcoholic fatty liver disease and its relations with adiponectin World Chin J Digestology 14 2006 1326 1329
    • (2006) World Chin J Digestology , vol.14 , pp. 1326-1329
    • Cui, K.Q.1    Zhao, X.W.2    Zhang, Y.3    Kang, X.H.4    Meng, J.5    Chen, X.L.6
  • 22
    • 44449087559 scopus 로고    scopus 로고
    • Application of adiponectin, TNF-α and ferrtin in type 2 diabetes with intrahepatic lipid infiltration
    • C Zhu, H Zhou, Y Han, L Ling, and G Huang Application of adiponectin, TNF-α and ferrtin in type 2 diabetes with intrahepatic lipid infiltration Nuclear Techniques 31 2008 356 359
    • (2008) Nuclear Techniques , vol.31 , pp. 356-359
    • Zhu, C.1    Zhou, H.2    Han, Y.3    Ling, L.4    Huang, G.5
  • 23
    • 84905391786 scopus 로고    scopus 로고
    • Effect of piglitazone and metformin on retinol-binding protein-4 and adiponectin in patients with type 2 diabetes mellitus complicated with non-alcohol fatty acid liver diseases
    • L Yang, MQ Song, QL Zhang, L Shou, SF Zang, and YL Yang Effect of piglitazone and metformin on retinol-binding protein-4 and adiponectin in patients with type 2 diabetes mellitus complicated with non-alcohol fatty acid liver diseases Zhongguo Yi Xue Ke Xue Yuan Xue Bao 36 2014 309 312
    • (2014) Zhongguo Yi Xue Ke Xue Yuan Xue Bao , vol.36 , pp. 309-312
    • Yang, L.1    Song, M.Q.2    Zhang, Q.L.3    Shou, L.4    Zang, S.F.5    Yang, Y.L.6
  • 25
    • 53049101877 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis
    • GP Aithal, JA Thomas, PV Kaye, A Lawson, SD Ryder, I Spendlove, and et al. Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis Gastroenterology 135 2008 1176 1184
    • (2008) Gastroenterology , vol.135 , pp. 1176-1184
    • Aithal, G.P.1    Thomas, J.A.2    Kaye, P.V.3    Lawson, A.4    Ryder, S.D.5    Spendlove, I.6
  • 26
    • 70350064027 scopus 로고    scopus 로고
    • Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis
    • A Gastaldelli, SA Harrison, R Belfort-Aguilar, LJ Hardies, B Balas, S Schenker, and et al. Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis Hepatology 50 2009 1087 1093
    • (2009) Hepatology , vol.50 , pp. 1087-1093
    • Gastaldelli, A.1    Harrison, S.A.2    Belfort-Aguilar, R.3    Hardies, L.J.4    Balas, B.5    Schenker, S.6
  • 28
    • 34548306770 scopus 로고    scopus 로고
    • The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis
    • G Lutchman, A Modi, DE Kleiner, K Promrat, T Heller, M Ghany, and et al. The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis Hepatology 46 2007 424 429
    • (2007) Hepatology , vol.46 , pp. 424-429
    • Lutchman, G.1    Modi, A.2    Kleiner, D.E.3    Promrat, K.4    Heller, T.5    Ghany, M.6
  • 29
    • 33751545838 scopus 로고    scopus 로고
    • A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
    • R Belfort, SA Harrison, K Brown, C Darland, J Finch, J Hardies, and et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis N Engl J Med 355 2006 2297 2307
    • (2006) N Engl J Med , vol.355 , pp. 2297-2307
    • Belfort, R.1    Harrison, S.A.2    Brown, K.3    Darland, C.4    Finch, J.5    Hardies, J.6
  • 30
    • 33746340885 scopus 로고    scopus 로고
    • Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: Relationship to histological improvement
    • G Lutchman, K Promrat, DE Kleiner, T Heller, MG Ghany, JA Yanovski, and et al. Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: relationship to histological improvement Clin Gastroenterol Hepatol 4 2006 1048 1052
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 1048-1052
    • Lutchman, G.1    Promrat, K.2    Kleiner, D.E.3    Heller, T.4    Ghany, M.G.5    Yanovski, J.A.6
  • 31
    • 46349088361 scopus 로고    scopus 로고
    • Rosiglitazone for nonalcoholic steatohepatitis: One-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial
    • V Ratziu, P Giral, S Jacqueminet, F Charlotte, A Hartemann-Heurtier, L Serfaty, and et al. Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial Gastroenterology 135 2008 100 110
    • (2008) Gastroenterology , vol.135 , pp. 100-110
    • Ratziu, V.1    Giral, P.2    Jacqueminet, S.3    Charlotte, F.4    Hartemann-Heurtier, A.5    Serfaty, L.6
  • 32
    • 84871045264 scopus 로고    scopus 로고
    • A randomized controlled trial comparing efficacy of pentoxifylline and pioglitazone on metabolic factors and liver histology in patients with non-alcoholic steatohepatitis
    • BC Sharma, A Kumar, V Garg, RS Reddy, P Sakhuja, and SK Sarin A randomized controlled trial comparing efficacy of pentoxifylline and pioglitazone on metabolic factors and liver histology in patients with non-alcoholic steatohepatitis J Clin Exp Hepatol 2 2012 333 337
    • (2012) J Clin Exp Hepatol , vol.2 , pp. 333-337
    • Sharma, B.C.1    Kumar, A.2    Garg, V.3    Reddy, R.S.4    Sakhuja, P.5    Sarin, S.K.6
  • 34
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • DE Kleiner, EM Brunt, NM Van, C Behling, MJ Contos, OW Cummings, and et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease Hepatology 41 2005 1313 1321
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van, N.M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 36
    • 84938057875 scopus 로고    scopus 로고
    • Liver fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease
    • P Angulo, DE Kleiner, S Dam-Larsen, LA Adams, ES Bjornsson, P Charatcharoenwitthaya, and et al. Liver fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease Gastroenterology 149 2015 389 397
    • (2015) Gastroenterology , vol.149 , pp. 389-397
    • Angulo, P.1    Kleiner, D.E.2    Dam-Larsen, S.3    Adams, L.A.4    Bjornsson, E.S.5    Charatcharoenwitthaya, P.6
  • 37
    • 84941652715 scopus 로고    scopus 로고
    • Diabetes: Advances in Diagnosis and Treatment
    • DM Nathan Diabetes: Advances in Diagnosis and Treatment JAMA 314 2015 1052 1062
    • (2015) JAMA , vol.314 , pp. 1052-1062
    • Nathan, D.M.1
  • 38
    • 84959271416 scopus 로고    scopus 로고
    • Evaluation of the synuclein-gamma (SNCG) gene as a PPARgamma target in murine adipocytes, dorsal root ganglia somatosensory neurons, and human adipose tissue
    • TN Dunn, T Akiyama, HW Lee, JB Kim, TA Knotts, SR Smith, and et al. Evaluation of the synuclein-gamma (SNCG) gene as a PPARgamma target in murine adipocytes, dorsal root ganglia somatosensory neurons, and human adipose tissue PLoS One 10 2015 e0115830
    • (2015) PLoS One , vol.10
    • Dunn, T.N.1    Akiyama, T.2    Lee, H.W.3    Kim, J.B.4    Knotts, T.A.5    Smith, S.R.6
  • 39
    • 84863508993 scopus 로고    scopus 로고
    • Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling
    • K Imajo, K Fujita, M Yoneda, Y Nozaki, Y Ogawa, Y Shinohara, and et al. Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling Cell Metab 16 2012 44 54
    • (2012) Cell Metab , vol.16 , pp. 44-54
    • Imajo, K.1    Fujita, K.2    Yoneda, M.3    Nozaki, Y.4    Ogawa, Y.5    Shinohara, Y.6
  • 40
    • 84923597485 scopus 로고    scopus 로고
    • Leptin in nonalcoholic fatty liver disease: A narrative review
    • SA Polyzos, J Kountouras, and CS Mantzoros Leptin in nonalcoholic fatty liver disease: a narrative review Metabolism 64 2015 60 78
    • (2015) Metabolism , vol.64 , pp. 60-78
    • Polyzos, S.A.1    Kountouras, J.2    Mantzoros, C.S.3
  • 41
    • 85027945646 scopus 로고    scopus 로고
    • The potential adverse role of leptin resistance in nonalcoholic fatty liver disease: A hypothesis based on critical review of literature
    • SA Polyzos, J Kountouras, C Zavos, and G Deretzi The potential adverse role of leptin resistance in nonalcoholic fatty liver disease: a hypothesis based on critical review of literature J Clin Gastroenterol 45 2011 50 54
    • (2011) J Clin Gastroenterol , vol.45 , pp. 50-54
    • Polyzos, S.A.1    Kountouras, J.2    Zavos, C.3    Deretzi, G.4
  • 43
    • 54949138357 scopus 로고    scopus 로고
    • Pioglitazone acutely stimulates adiponectin secretion from mouse and human adipocytes via activation of the phosphatidylinositol 3'-kinase
    • RI Pereira, JW Leitner, C Erickson, and B Draznin Pioglitazone acutely stimulates adiponectin secretion from mouse and human adipocytes via activation of the phosphatidylinositol 3'-kinase Life Sci 83 2008 638 643
    • (2008) Life Sci , vol.83 , pp. 638-643
    • Pereira, R.I.1    Leitner, J.W.2    Erickson, C.3    Draznin, B.4
  • 44
    • 79551499779 scopus 로고    scopus 로고
    • Eicosapentaenoic acid and rosiglitazone increase adiponectin in an additive and PPARgamma-dependent manner in human adipocytes
    • JM Tishinsky, DW Ma, and LE Robinson Eicosapentaenoic acid and rosiglitazone increase adiponectin in an additive and PPARgamma-dependent manner in human adipocytes Obesity 19 2011 262 268
    • (2011) Obesity , vol.19 , pp. 262-268
    • Tishinsky, J.M.1    Ma, D.W.2    Robinson, L.E.3
  • 45
    • 60849100836 scopus 로고    scopus 로고
    • The development of INT131 as a Selective PPARgamma Modulator: Approach to a safer insulin sensitizer
    • LS Higgins, and CS Mantzoros The development of INT131 as a Selective PPARgamma Modulator: approach to a safer insulin sensitizer PPAR Res 2008 2008 936906
    • (2008) PPAR Res , vol.2008
    • Higgins, L.S.1    Mantzoros, C.S.2
  • 46
    • 77955285732 scopus 로고    scopus 로고
    • Rosiglitazone revisited: An updated meta-analysis of risk for myocardial infarction and cardiovascular mortality
    • SE Nissen, and K Wolski Rosiglitazone revisited: an updated meta-analysis of risk for myocardial infarction and cardiovascular mortality Arch Intern Med 170 2010 1191 1201
    • (2010) Arch Intern Med , vol.170 , pp. 1191-1201
    • Nissen, S.E.1    Wolski, K.2
  • 47
    • 79956217900 scopus 로고    scopus 로고
    • Risk of bladder cancer among diabetic patients treated with pioglitazone: Interim report of a longitudinal cohort study
    • JD Lewis, A Ferrara, T Peng, M Hedderson, WB Bilker, CP Quesenberry Jr., and et al. Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study Diabetes Care 34 2011 916 922
    • (2011) Diabetes Care , vol.34 , pp. 916-922
    • Lewis, J.D.1    Ferrara, A.2    Peng, T.3    Hedderson, M.4    Bilker, W.B.5    Quesenberry, C.P.6
  • 48
    • 79955064893 scopus 로고    scopus 로고
    • Selective modulation of PPARgamma activity can lower plasma glucose without typical thiazolidinedione side-effects in patients with type 2 diabetes
    • FL Dunn, LS Higgins, J Fredrickson, and AM DePaoli Selective modulation of PPARgamma activity can lower plasma glucose without typical thiazolidinedione side-effects in patients with type 2 diabetes J Diabetes Complications 25 2011 151 158
    • (2011) J Diabetes Complications , vol.25 , pp. 151-158
    • Dunn, F.L.1    Higgins, L.S.2    Fredrickson, J.3    DePaoli, A.M.4
  • 49
    • 84903550477 scopus 로고    scopus 로고
    • Can a selective PPARgamma modulator improve glycemic control in patients with type 2 diabetes with fewer side effects compared with pioglitazone?
    • AM DePaoli, LS Higgins, RR Henry, C Mantzoros, and FL Dunn Can a selective PPARgamma modulator improve glycemic control in patients with type 2 diabetes with fewer side effects compared with pioglitazone? Diabetes Care 37 2014 1918 1923
    • (2014) Diabetes Care , vol.37 , pp. 1918-1923
    • DePaoli, A.M.1    Higgins, L.S.2    Henry, R.R.3    Mantzoros, C.4    Dunn, F.L.5
  • 50
    • 78649741621 scopus 로고    scopus 로고
    • The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats
    • S Liu, HJ Wu, ZQ Zhang, Q Chen, B Liu, JP Wu, and et al. The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats Eur J Pharmacol 650 2011 384 389
    • (2011) Eur J Pharmacol , vol.650 , pp. 384-389
    • Liu, S.1    Wu, H.J.2    Zhang, Z.Q.3    Chen, Q.4    Liu, B.5    Wu, J.P.6
  • 51
    • 79751491258 scopus 로고    scopus 로고
    • Adenovirus-mediated peroxisome proliferator activated receptor gamma overexpression prevents nutritional fibrotic steatohepatitis in mice
    • YM Nan, F Han, LB Kong, SX Zhao, RQ Wang, WJ Wu, and et al. Adenovirus-mediated peroxisome proliferator activated receptor gamma overexpression prevents nutritional fibrotic steatohepatitis in mice Scand J Gastroenterol 46 2011 358 369
    • (2011) Scand J Gastroenterol , vol.46 , pp. 358-369
    • Nan, Y.M.1    Han, F.2    Kong, L.B.3    Zhao, S.X.4    Wang, R.Q.5    Wu, W.J.6
  • 52
    • 85048900823 scopus 로고    scopus 로고
    • Statins, antidiabetic medications and liver histology in patients with diabetes with non-alcoholic fatty liver disease
    • F Nascimbeni, J Aron-Wisnewsky, R Pais, J Tordjman, C Poitou, F Charlotte, and et al. Statins, antidiabetic medications and liver histology in patients with diabetes with non-alcoholic fatty liver disease BMJ Open Gastro 3 2016 e000075
    • (2016) BMJ Open Gastro , vol.3
    • Nascimbeni, F.1    Aron-Wisnewsky, J.2    Pais, R.3    Tordjman, J.4    Poitou, C.5    Charlotte, F.6
  • 53
    • 0037267068 scopus 로고    scopus 로고
    • How important are comprehensive literature searches and the assessment of trial quality in systematic reviews? Empirical study
    • M Egger, P Juni, C Bartlett, F Holenstein, and J Sterne How important are comprehensive literature searches and the assessment of trial quality in systematic reviews? Empirical study Health Technol Assess 7 2003 1 76
    • (2003) Health Technol Assess , vol.7 , pp. 1-76
    • Egger, M.1    Juni, P.2    Bartlett, C.3    Holenstein, F.4    Sterne, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.