Apple Polyphenol Phloretin Inhibits Colorectal Cancer Cell Growth via Inhibition of the Type 2 Glucose Transporter and Activation of p53-Mediated Signaling

Journal of Agricultural and Food Chemistry

Volumn 64, Issue 36, 2016, Pages 6826-6837

  Lin, Sheng Tsai ^a,j   Tu, Shih Hsin ^b,c,d   Yang, Po Sheng ^e,f,g   Hsu, Sung Po ^c,j   Lee, Wei Hwa ^a,c   Ho, Chi Tang ^h   Wu, Chih Hsiung ^c,i   Lai, Yu Hsin ^a,j   Chen, Ming Yao ^a,j   Chen, Li Ching ^b,d,j  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e MACKAY MEMORIAL HOSPITAL   (Taiwan)

^f MACKAY MEDICAL COLLEGE   (Taiwan)

^g Department of Intelligent Technology and Long Term Care   (Taiwan)

^h RUTGERS UNIVERSITY   (United States)

ⁱ EN CHU KONG HOSPITAL   (Taiwan)

^j TAIPEI MEDICAL UNIVERSITY   (Taiwan)

more..

Author keywords

apple polyphenol; colon cancer; glucose transporter 2; p53; phloretin

Indexed keywords

CELL GROWTH; CELLS; CYTOLOGY; DISEASES; FRUITS; GLUCOSE; GROWTH KINETICS; TISSUE; TUMORS;

APPLE POLYPHENOL; COLON CANCER; COLORECTAL CANCER CELL; EXPRESSION VECTORS; GLUCOSE TRANSPORTERS; HEPATOCYTE NUCLEAR FACTORS; PHLORETIN; PROTEIN EXPRESSIONS;

CELL SIGNALING;

ANTIOXIDANT; GLUCOSE; GLUCOSE TRANSPORTER 2; HEPATOCYTE NUCLEAR FACTOR 6; MESSENGER RNA; ONECUT1 PROTEIN, HUMAN; PHLORETIN; POLYPHENOL; PROTEIN P53; SLC2A2 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

AGED; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; CANCER STAGING; CELL CYCLE CHECKPOINT; CHEMISTRY; COLORECTAL TUMOR; FEMALE; HUMAN; MALE; MALUS; METABOLISM; MOUSE; NUDE MOUSE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AGED; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 2; HEPATOCYTE NUCLEAR FACTOR 6; HUMANS; MALE; MALUS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM STAGING; PHLORETIN; POLYPHENOLS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84988024370     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.6b02861     Document Type: Article

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