An mTORC1-Mdm2-Drosha axis for miRNA biogenesis in response to glucose- and amino acid-deprivation

Molecular Cell

Volumn 57, Issue 4, 2015, Pages 708-720

  Ye, Peiying ^a   Liu, Yu ^b   Chen, Chong ^b   Tang, Fei ^a   Wu, Qi ^c   Wang, Xiang ^a   Liu, Chang Gong ^d   Liu, Xiuping ^d   Liu, Runhua ^e   Liu, Yang ^a   Zheng, Pan ^a  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^b SICHUAN UNIVERSITY   (China)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DROSHA; GLUCOSE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MICRORNA; PROTEIN DERIVATIVE; PROTEIN MDM2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; DROSHA PROTEIN, MOUSE; MDM2 PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PROTEIN P53; RIBONUCLEASE III; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOGENESIS; CONTROLLED STUDY; DOWN REGULATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RNA PROCESSING; UBIQUITINATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; METABOLISM; PHYSIOLOGY;

MAMMALIA; RAPTORES;

AMINO ACIDS; ANIMALS; GENE EXPRESSION REGULATION; GLUCOSE; HELA CELLS; HUMANS; MICE, INBRED C57BL; MICRORNAS; MULTIPROTEIN COMPLEXES; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MDM2; RIBONUCLEASE III; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION;

EID: 84923837881     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.12.034     Document Type: Article

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