Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy

Nano Letters

Volumn 16, Issue 9, 2016, Pages 5503-5513

  Wang, Dangge ^a,b   Wang, Tingting ^a,b   Liu, Jianping ^a   Yu, Haijun ^a   Jiao, Shi ^c   Feng, Bing ^a,b   Zhou, Fangyuan ^a   Fu, Yuanlei ^a   Yin, Qi ^a   Zhang, Pengcheng ^a   Zhang, Zhiwen ^a   Zhou, Zhaocai ^c   Li, Yaping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

acid activatable; cancer immunotherapy; Micelleplexes; photodynamic therapy; RNA interference

Indexed keywords

CELL DEATH; CELLS; CYTOLOGY; DISEASES; ONCOLOGY; PH; PHOTOSENSITIZERS; RNA; T-CELLS; TUMORS;

ANTI-TUMOR ACTIVITIES; CANCER IMMUNOTHERAPY; FLUORESCENCE IMAGING; MICELLEPLEXES; PHOTODYNAMIC THERAPY (PDT); PROGRAMMED CELL DEATHS; RNA INTERFERENCE; SMALL INTERFERING RNA (SIRNA);

PHOTODYNAMIC THERAPY;

PHOTOSENSITIZING AGENT; PROGRAMMED DEATH 1 RECEPTOR;

ANIMAL; C57BL MOUSE; DRUG SCREENING; EXPERIMENTAL MELANOMA; IMMUNOTHERAPY; MOUSE; PHOTOCHEMOTHERAPY; T LYMPHOCYTE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; IMMUNOTHERAPY; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROGRAMMED CELL DEATH 1 RECEPTOR; T-LYMPHOCYTES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84987754219     PISSN: 15306984     EISSN: 15306992     Source Type: Journal    
DOI: 10.1021/acs.nanolett.6b01994     Document Type: Article

References (45)

1. McNutt, M. Science 2013, 342, 1417-1417 10.1126/science.1249481
2. Lynn, G. M.; Laga, R.; Darrah, P. A.; Ishizuka, A. S.; Balaci, A. J.; Dulcey, A. E.; Pechar, M.; Pola, R.; Gerner, M. Y.; Yamamoto, A.; Buechler, C. R.; Quinn, K. M.; Smelkinson, M. G.; Vanek, O.; Cawood, R.; Hills, T.; Vasalatiy, O.; Kastenmuller, K.; Francica, J. R.; Stutts, L.; Tom, J. K.; Ryu, K. A.; Esser-Kahn, A. P.; Etrych, T.; Fisher, K. D.; Seymour, L. W.; Seder, R. A. Nat. Biotechnol. 2015, 33, 1201-1210 10.1038/nbt.3371
3. Kim, S. Y.; Heo, M. B.; Hwang, G. S.; Jung, Y.; Choi, D. Y.; Park, Y. M.; Lim, Y. T. Angew. Chem., Int. Ed. 2015, 54, 8139-8143 10.1002/anie.201501380
4. Moon, J. J.; Huang, B.; Irvine, D. J. Adv. Mater. 2012, 24, 3724-3746 10.1002/adma.201200446
5. Liu, H.; Moynihan, K. D.; Zheng, Y.; Szeto, G. L.; Li, A. V.; Huang, B.; Van Egeren, D. S.; Park, C.; Irvine, D. J. Nature 2014, 507, 519-522 10.1038/nature12978
6. Castano, A. P.; Mroz, P.; Hamblin, M. R. Nat. Rev. Cancer 2006, 6, 535-545 10.1038/nrc1894
7. Turan, I. S.; Yildiz, D.; Turksoy, A.; Gunaydin, G.; Akkaya, E. U. Angew. Chem., Int. Ed. 2016, 55, 2875-2878 10.1002/anie.201511345
8. Idris, N. M.; Jayakumar, M. K. G.; Bansal, A.; Zhang, Y. Chem. Soc. Rev. 2015, 44, 1449-1478 10.1039/C4CS00158C
9. Srivastava, P. Nat. Rev. Immunol. 2002, 2, 185-194 10.1038/nri749
10. Ryter, S. W.; Gomer, C. J. Photochem. Photobiol. 1993, 58, 753-756 10.1111/j.1751-1097.1993.tb04964.x
11. Chen, Q.; Liang, C.; Wang, C.; Liu, Z. Adv. Mater. 2015, 27, 903-910 10.1002/adma.201404308
12. Korbelik, M.; Sun, J.; Cecic, I. Cancer Res. 2005, 65, 1018-1026
13. Muhanna, N.; Cui, L.; Chan, H.; Burgess, L.; Jin, C. S.; MacDonald, T. D.; Huynh, E.; Wang, F.; Chen, J.; Irish, J. C.; Zheng, G. Clin. Cancer Res. 2016, 22, 961-970 10.1158/1078-0432.CCR-15-1235
14. Smith, A. M.; Mancini, M. C.; Nie, S. Nat. Nanotechnol. 2009, 4, 710-711 10.1038/nnano.2009.326
15. Guo, C. S.; Yu, H. J.; Feng, B.; Gao, W. D.; Yan, M.; Zhang, Z. W.; Li, Y. P.; Liu, S. Q. Biomaterials 2015, 52, 407-416 10.1016/j.biomaterials.2015.02.054
16. Jin, C. S.; Lovell, J. F.; Chen, J.; Zheng, G. ACS Nano 2013, 7, 2541-2550 10.1021/nn3058642
17. Liu, Y. Y.; Liu, Y.; Bu, W. B.; Cheng, C.; Zuo, C. J.; Xiao, Q. F.; Sun, Y.; Ni, D. L.; Zhang, C.; Liu, J. A.; Shi, J. L. Angew. Chem., Int. Ed. 2015, 54, 8105-8109 10.1002/anie.201500478
18. Castano, A. P.; Mroz, P.; Wu, M. X.; Hamblin, M. R. Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 5495-5500 10.1073/pnas.0709256105
19. Hanahan, D.; Weinberg, R. A. Cell 2000, 100, 57-70 10.1016/S0092-8674(00)81683-9
20. Zou, W.; Wolchok, J. D.; Chen, L. Sci. Transl. Med. 2016, 8, 328rv4 10.1126/scitranslmed.aad7118
21. Domling, A.; Holak, T. A. Angew. Chem., Int. Ed. 2014, 53, 2286-2288 10.1002/anie.201307906
22. Pardoll, D. M. Nat. Rev. Cancer 2012, 12, 252-264 10.1038/nrc3239
23. Sidaway, P. Nat. Rev. Clin. Oncol. 2016, 13, 134 10.1038/nrclinonc.2016.5
24. Karin, M. Nature 2006, 441, 431-436 10.1038/nature04870
25. Wang, C.; Ye, Y.; Hochu, G. M.; Sadeghifar, H.; Gu, Z. Nano Lett. 2016, 16, 2334-2340 10.1021/acs.nanolett.5b05030
26. Chang, H. N.; Liu, B. Y.; Qi, Y. K.; Zhou, Y.; Chen, Y. P.; Pan, K. M.; Li, W. W.; Zhou, X. M.; Ma, W. W.; Fu, C. Y.; Qi, Y. M.; Liu, L.; Gao, Y. F. Angew. Chem., Int. Ed. 2015, 54, 11760-11764 10.1002/anie.201506225
27. Gao, L.; Zhang, C.; Gao, D.; Liu, H.; Yu, X.; Lai, J.; Wang, F.; Lin, J.; Liu, Z. Theranostics 2016, 6, 627-637 10.7150/thno.14792
28. Yu, H.; Zou, Y.; Wang, Y.; Huang, X.; Huang, G.; Sumer, B. D.; Boothman, D. A.; Gao, J. ACS Nano 2011, 5, 9246-9255 10.1021/nn203503h
29. Yu, H.; Xu, Z.; Wang, D.; Chen, X.; Zhang, Z.; Yin, Q.; Li, Y. Polym. Chem. 2013, 4, 5052-5055 10.1039/c3py00849e
30. Wang, Y.; Zhou, K.; Huang, G.; Hensley, C.; Huang, X.; Ma, X.; Zhao, T.; Sumer, B. D.; DeBerardinis, R. J.; Gao, J. Nat. Mater. 2014, 13, 204-212 10.1038/nmat3819
31. Jin, C. S.; Cui, L. Y.; Wang, F.; Chen, J.; Zheng, G. Adv. Healthcare Mater. 2014, 3, 1240-1249 10.1002/adhm.201300651
32. Lovell, J. F.; Jin, C. S.; Huynh, E.; Jin, H. L.; Kim, C.; Rubinstein, J. L.; Chan, W. C. W.; Cao, W. G.; Wang, L. V.; Zheng, G. Nat. Mater. 2011, 10, 324-332 10.1038/nmat2986
33. Wang, T.; Wang, D.; Yu, H.; Wang, M.; Liu, J.; Feng, B.; Zhou, F.; Yin, Q.; Zhang, Z.; Huang, Y.; Li, Y. ACS Nano 2016, 10, 3496-3508 10.1021/acsnano.5b07706
34. Casey, J. R.; Grinstein, S.; Orlowski, J. Nat. Rev. Mol. Cell Biol. 2010, 11, 50-61 10.1038/nrm2820
35. Wang, H.; Wang, Y.; Hu, J.; Li, T.; Liu, H.; Zhang, Q.; Cheng, Y.; Wang, Y. Angew. Chem., Int. Ed. 2015, 54, 11647-11651 10.1002/anie.201501461
36. Yu, H.; Nie, Y.; Dohmen, C.; Li, Y.; Wagner, E. Biomacromolecules 2011, 12, 2039-2047 10.1021/bm101464n
37. Wang, D. G.; Wang, T. T.; Xu, Z. A.; Yu, H. J.; Feng, B.; Zhang, J. Y.; Guo, C. Y.; Yin, Q.; Zhang, Z. W.; Li, Y. P. Small 2016, 12, 488-498 10.1002/smll.201502913
38. Liu, W.; Oseroff, A. R.; Baumann, H. Cancer Res. 2004, 64, 6579-6587 10.1158/0008-5472.CAN-04-1580
39. Mroz, P.; Vatansever, F.; Muchowicz, A.; Hamblin, M. R. Cancer Res. 2013, 73, 6462-6470 10.1158/0008-5472.CAN-11-2572
40. Mittendorf, E. A.; Philips, A. V.; Meric-Bernstam, F.; Qiao, N.; Wu, Y.; Harrington, S.; Su, X.; Wang, Y.; Gonzalez-Angulo, A. M.; Akcakanat, A.; Chawla, A.; Curran, M.; Hwu, P.; Sharma, P.; Litton, J. K.; Molldrem, J. J.; Alatrash, G. Cancer Immunol. Res. 2014, 2, 361-370 10.1158/2326-6066.CIR-13-0127
41. Bendz, H.; Ruhland, S. C.; Pandya, M. J.; Hainzl, O.; Riegelsberger, S.; Brauchle, C.; Mayer, M. P.; Buchner, J.; Issels, R. D.; Noessner, E. J. Biol. Chem. 2007, 282, 31688-31702 10.1074/jbc.M704129200
42. Melief, C. J. Immunity 2008, 29, 372-383 10.1016/j.immuni.2008.08.004
43. Dolina, J. S.; Sung, J. S.; Novobrantseva, T. I.; Nguyen, T. M.; Hahn, Y. S. Mol. Ther. - Nucleic Acids 2013, 2, e72 10.1038/mtna.2012.63
44. Kleinovink, J. W.; van Driel, P. B.; Snoeks, T.; Prokopi, J. N.; Fransen, M. F.; Cruz, L. J.; Mezzanotte, L.; Chan, A.; Löwik, C. W.; Ossendorp, F. Clin. Cancer Res. 2016, 22, 1459-1468 10.1158/1078-0432.CCR-15-0515
45. Irvine, D. J.; Hanson, M. C.; Rakhra, K.; Tokatlian, T. Chem. Rev. 2015, 115, 11109-11146 10.1021/acs.chemrev.5b00109