NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Brandt, Moritz ^a   Garlapati, Venkata ^a   Oelze, Matthias ^a   Sotiriou, Efthymios ^a   Knorr, Maike ^a   Kröller Schön, Swenja ^a   Kossmann, Sabine ^a   Schönfelder, Tanja ^a   Morawietz, Henning ^b   Schulz, Eberhard ^a   Schultheiss, Heinz Peter ^c   Daiber, Andreas ^a   Münzel, Thomas ^a   Wenzel, Philip ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c Institut Kardiale Diagnostik und Therapie GmbH Berlin   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALDEHYDE DEHYDROGENASE ISOENZYME 2; ALDH2 PROTEIN, MOUSE; CYBB PROTEIN, HUMAN; CYBB PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE;

ALCOHOLIC CARDIOMYOPATHY; ANIMAL; CARDIAC MUSCLE CELL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HEART FAILURE; HUMAN; METABOLISM; MITOCHONDRION; MOUSE; PATHOLOGY;

ACETALDEHYDE; ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; ANIMALS; CARDIOMYOPATHY, ALCOHOLIC; DISEASE MODELS, ANIMAL; ETHANOL; GENE EXPRESSION REGULATION; HEART FAILURE; HUMANS; MICE; MITOCHONDRIA; MYOCYTES, CARDIAC; NADPH OXIDASE 2; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 84987732895     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep32554     Document Type: Article

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