메뉴 건너뛰기




Volumn 2, Issue OCT, 2014, Pages

Sensing marine biomolecules: Smell, taste, and the evolutionary transition from aquatic to terrestrial life

Author keywords

GPCRs; Gustation; Marine natural products; Odorant receptors; Olfaction; Solubility; Terpenoids; Volatility

Indexed keywords


EID: 84987629372     PISSN: None     EISSN: 22962646     Source Type: Journal    
DOI: 10.3389/fchem.2014.00092     Document Type: Article
Times cited : (50)

References (50)
  • 1
    • 27644437576 scopus 로고    scopus 로고
    • Olfaction: diverse species, conserved principles
    • Ache, B. W., and Young, J. M. (2005). Olfaction: diverse species, conserved principles. Neuron 48, 417-430. doi: 10.1016/j.neuron.2005.10.022
    • (2005) Neuron , vol.48 , pp. 417-430
    • Ache, B.W.1    Young, J.M.2
  • 2
    • 84876271982 scopus 로고    scopus 로고
    • The African coelacanth genome provides insights into tetrapod evolution
    • Amemiya, C. T., Alföldi, J., Lee, A. P., Fan, S., Philippe, H., MacCallum, I., et al. (2013). The African coelacanth genome provides insights into tetrapod evolution. Nature 496, 311-316. doi: 10.1038/nature12027
    • (2013) Nature , vol.496 , pp. 311-316
    • Amemiya, C.T.1    Alföldi, J.2    Lee, A.P.3    Fan, S.4    Philippe, H.5    MacCallum, I.6
  • 3
    • 84883326014 scopus 로고    scopus 로고
    • 'Aquatic odour dispersal fields: opportunities and limits of detection, communication, and navigation'
    • eds C. Brönmark and L. A. Hansson (Oxford: Oxford University Press)
    • Atema, J. (2012). "Aquatic odour dispersal fields: opportunities and limits of detection, communication, and navigation, " in Chemical Ecology in Aquatic Systems, eds C. Brönmark and L. A. Hansson (Oxford: Oxford University Press), 1-18.
    • (2012) Chemical Ecology in Aquatic Systems , pp. 1-18
    • Atema, J.1
  • 4
    • 67449127534 scopus 로고    scopus 로고
    • Potential anti-cancer activity of furanodiene
    • Ba, Z., Zheng, Y., Zhang, H., Sun, X., and Lin, D. (2009). Potential anti-cancer activity of furanodiene. Chin. J. Cancer Res. 21, 154-158. doi: 10.1007/s11670-009-0154-0
    • (2009) Chin. J. Cancer Res , vol.21 , pp. 154-158
    • Ba, Z.1    Zheng, Y.2    Zhang, H.3    Sun, X.4    Lin, D.5
  • 5
    • 58149099733 scopus 로고    scopus 로고
    • Drought, warming and soil fertilization effects on leaf volatile terpene concentrations in Pinus halepensis and Quercus ilex
    • Blanch, J.-S., Peñuelas, J., Sardans, J., and Llusià, J. (2009). Drought, warming and soil fertilization effects on leaf volatile terpene concentrations in Pinus halepensis and Quercus ilex. Acta Physiol. Plant. 31, 207-218. doi: 10.1007/s11738-008-0221-z
    • (2009) Acta Physiol. Plant , vol.31 , pp. 207-218
    • Blanch, J.-S.1    Peñuelas, J.2    Sardans, J.3    Llusià, J.4
  • 6
    • 84970571524 scopus 로고
    • Studies of Australian soft corals. XX. A new sesquiterpene furan from soft corals of the family Xeniidae and an examination of Clavularia inflata from north Queensland waters
    • Bowden, B. F., Braekman, J., and Mitchell, S. J. (1980). Studies of Australian soft corals. XX. A new sesquiterpene furan from soft corals of the family Xeniidae and an examination of Clavularia inflata from north Queensland waters. Aust. J. Chem. 33, 927-932. doi: 10.1071/CH9800927
    • (1980) Aust. J. Chem , vol.33 , pp. 927-932
    • Bowden, B.F.1    Braekman, J.2    Mitchell, S.J.3
  • 8
    • 84902172106 scopus 로고    scopus 로고
    • Antiproliferative evaluation of isofuranodiene on breast and prostate cancer cell lines
    • Buccioni, M., Dal Ben, D., Lambertucci, C., Maggi, F., Papa, F., Thomas, A., et al. (2014). Antiproliferative evaluation of isofuranodiene on breast and prostate cancer cell lines. Sci. World J. 2014:264829. doi: 10.1155/2014/264829
    • (2014) Sci. World J , vol.2014
    • Buccioni, M.1    Dal Ben, D.2    Lambertucci, C.3    Maggi, F.4    Papa, F.5    Thomas, A.6
  • 9
    • 0037660915 scopus 로고    scopus 로고
    • 'Smell and taste: the chemical senses'
    • eds E. R. Kandel, J. H. Schwartz, and T. M. Jessell (New York, NY: McGraw-Hill)
    • Buck, L. (2000). "Smell and taste: the chemical senses, " in Principles of Neural Science, eds E. R. Kandel, J. H. Schwartz, and T. M. Jessell (New York, NY: McGraw-Hill), 625-652.
    • (2000) Principles of Neural Science , pp. 625-652
    • Buck, L.1
  • 10
    • 0025825726 scopus 로고
    • A novel multigene family may encode odorant receptors: a molecular basis for odor recognition
    • Buck, L., and Axel, R. (1991). A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65, 175-187. doi: 10.1016/0092-8674(91)90418-X
    • (1991) Cell , vol.65 , pp. 175-187
    • Buck, L.1    Axel, R.2
  • 11
    • 84876427037 scopus 로고    scopus 로고
    • Packaging and delivery of chemical weapons: a defensive Trojan horse stratagem in chromodorid nudibranchs
    • Carbone, M., Gavagnin, M., Haber, M., Guo, Y.-W., Fontana, A., Manzo, E., et al. (2013). Packaging and delivery of chemical weapons: a defensive Trojan horse stratagem in chromodorid nudibranchs. PLoS ONE 8:e62075. doi: 10.1371/journal.pone.0062075
    • (2013) PLoS ONE , vol.8
    • Carbone, M.1    Gavagnin, M.2    Haber, M.3    Guo, Y.-W.4    Fontana, A.5    Manzo, E.6
  • 12
    • 70350312554 scopus 로고    scopus 로고
    • Amphioxus (Branchiostoma floridae) has orthologs of vertebrate odorant receptors
    • Churcher, A. M., and Taylor, J. S. (2009). Amphioxus (Branchiostoma floridae) has orthologs of vertebrate odorant receptors. BMC Evol. Biol. 9, 242-252. doi: 10.1186/1471-2148-9-242
    • (2009) BMC Evol. Biol , vol.9 , pp. 242-252
    • Churcher, A.M.1    Taylor, J.S.2
  • 13
    • 79954450931 scopus 로고    scopus 로고
    • The antiquity of chordate odorant receptors is revealed by the discovery of orthologs in the cnidarian Nematostella vectensis
    • Churcher, A. M., and Taylor, J. S. (2010). The antiquity of chordate odorant receptors is revealed by the discovery of orthologs in the cnidarian Nematostella vectensis. Genome Biol. Evol. 3, 36-43. doi: 10.1093/gbe/evq079
    • (2010) Genome Biol. Evol , vol.3 , pp. 36-43
    • Churcher, A.M.1    Taylor, J.S.2
  • 14
    • 0013021692 scopus 로고    scopus 로고
    • 'Marine natural products chemistry as an evolutionary narrative'
    • eds J. B. McClintock and B. J. Baker (Boca Raton: CRC Press)
    • Cimino, G., and Ghiselin, M. T. (2001). "Marine natural products chemistry as an evolutionary narrative, " in Marine Chemical Ecology, eds J. B. McClintock and B. J. Baker (Boca Raton: CRC Press), 115-154.
    • (2001) Marine Chemical Ecology , pp. 115-154
    • Cimino, G.1    Ghiselin, M.T.2
  • 15
    • 78149430303 scopus 로고    scopus 로고
    • Chemical defense and evolution of opisthobranch gastropods
    • Cimino, G., and Ghiselin, M. T. (2009). Chemical defense and evolution of opisthobranch gastropods. Proc. Calif. Acad. Sci. 60, 175-422.
    • (2009) Proc. Calif. Acad. Sci , vol.60 , pp. 175-422
    • Cimino, G.1    Ghiselin, M.T.2
  • 16
    • 0029431627 scopus 로고
    • Chemical aspects of Mass spawning in corals. II. Epi-thunbergol, the sperm attractant in the eggs of the soft coral Lobophytum crassum (Cnidaria, Octocorallia)
    • Coll, J. C., Leone, P. A., Bowden, B. F., Carroll, A. R., Konig, G. M., Heaton, A., et al. (1995). Chemical aspects of Mass spawning in corals. II. Epi-thunbergol, the sperm attractant in the eggs of the soft coral Lobophytum crassum (Cnidaria, Octocorallia). Mar. Biol. 123, 137-143. doi: 10.1007/BF00350332
    • (1995) Mar. Biol , vol.123 , pp. 137-143
    • Coll, J.C.1    Leone, P.A.2    Bowden, B.F.3    Carroll, A.R.4    Konig, G.M.5    Heaton, A.6
  • 17
    • 46949083034 scopus 로고    scopus 로고
    • Neural processing, perception, and behavioral responses to natural chemical stimuli by fish and crustaceans
    • Derby, C. D., and Sorensen, P. W. (2008). Neural processing, perception, and behavioral responses to natural chemical stimuli by fish and crustaceans. J. Chem. Ecol. 34, 898-914. doi: 10.1007/s10886-008-9489-0
    • (2008) J. Chem. Ecol , vol.34 , pp. 898-914
    • Derby, C.D.1    Sorensen, P.W.2
  • 19
    • 43649085247 scopus 로고    scopus 로고
    • "Evolution of vertebrate olfactory subsystems"
    • ed J. H. Kaas (Oxford: Academic Press)
    • Eisthen, H. L., and Polese, G. (2006). "Evolution of vertebrate olfactory subsystems, " in Evolution of Nervous Systems, Vol. 2, ed J. H. Kaas (Oxford: Academic Press), 355-406.
    • (2006) Evolution of Nervous Systems , vol.2 , pp. 355-406
    • Eisthen, H.L.1    Polese, G.2
  • 20
    • 0345412042 scopus 로고    scopus 로고
    • Sesquiterpene metabolites of the antarctic gorgonian Dasystenella acanthina
    • Gavagnin, M., Mollo, E., Castelluccio, F., Crispino, A., and Cimino, G. (2003). Sesquiterpene metabolites of the antarctic gorgonian Dasystenella acanthina. J. Nat. Prod. 66, 1517-1519. doi: 10.1021/np030201r
    • (2003) J. Nat. Prod , vol.66 , pp. 1517-1519
    • Gavagnin, M.1    Mollo, E.2    Castelluccio, F.3    Crispino, A.4    Cimino, G.5
  • 22
    • 66249131524 scopus 로고    scopus 로고
    • Marine chemical ecology: chemical signals and cues structure marine populations, communities, and ecosystems
    • Hay, M. E. (2009). Marine chemical ecology: chemical signals and cues structure marine populations, communities, and ecosystems. Ann. Rev. Mar. Sci. 1, 193-212. doi: 10.1146/annurev.marine.010908.163708
    • (2009) Ann. Rev. Mar. Sci , vol.1 , pp. 193-212
    • Hay, M.E.1
  • 23
    • 84981962866 scopus 로고
    • Signal substances and their reception in the sexual cycle of marine brown-algae
    • Jaenicke, L., and Boland, W. (1982). Signal substances and their reception in the sexual cycle of marine brown-algae. Angew. Chem. Int. Ed. 21, 643-653. doi: 10.1002/anie.198206433
    • (1982) Angew. Chem. Int. Ed , vol.21 , pp. 643-653
    • Jaenicke, L.1    Boland, W.2
  • 24
    • 84864330134 scopus 로고    scopus 로고
    • Transition from sea to land: olfactory function and constraints in the terrestrial hermit crab Coenobita clypeatus
    • Krång, A. S., Knaden, M., Steck, K., and Hansson, B. S. (2012). Transition from sea to land: olfactory function and constraints in the terrestrial hermit crab Coenobita clypeatus. Proc. R. Soc. Lond. B Biol. Sci. 279, 3510-3519. doi: 10.1098/rspb.2012.0596
    • (2012) Proc. R. Soc. Lond. B Biol. Sci , vol.279 , pp. 3510-3519
    • Krång, A.S.1    Knaden, M.2    Steck, K.3    Hansson, B.S.4
  • 25
    • 0034786449 scopus 로고    scopus 로고
    • Sequestered chemistry of the Arminacean nudibranch Leminda millecra in Algoa Bay, South Africa
    • McPhail, K. L., Davies-Coleman, M. T., and Starmer, J. (2001). Sequestered chemistry of the Arminacean nudibranch Leminda millecra in Algoa Bay, South Africa. J. Nat. Prod. 64, 1183-1190. doi: 10.1021/np010085x
    • (2001) J. Nat. Prod , vol.64 , pp. 1183-1190
    • McPhail, K.L.1    Davies-Coleman, M.T.2    Starmer, J.3
  • 27
    • 33645951439 scopus 로고    scopus 로고
    • Maps of odorant molecular features in the mammalian olfactory bulb
    • Mori, K., Takahashi, Y. K., Igarashi, K. M., and Yamaguchi, M. (2006). Maps of odorant molecular features in the mammalian olfactory bulb. Physiol. Rev. 86, 409-433. doi: 10.1152/physrev.00021.2005
    • (2006) Physiol. Rev , vol.86 , pp. 409-433
    • Mori, K.1    Takahashi, Y.K.2    Igarashi, K.M.3    Yamaguchi, M.4
  • 28
    • 79959669711 scopus 로고    scopus 로고
    • A large-scale analysis of odor coding in the olfactory epithelium
    • Nara, K., Saraiva, L. R., Ye, X., and Buck, L. B. (2011). A large-scale analysis of odor coding in the olfactory epithelium. J. Neurosci. 31, 9179-9191. doi: 10.1523/JNEUROSCI.1282-11.2011
    • (2011) J. Neurosci , vol.31 , pp. 9179-9191
    • Nara, K.1    Saraiva, L.R.2    Ye, X.3    Buck, L.B.4
  • 29
    • 84860299628 scopus 로고    scopus 로고
    • Olfactory receptor multigene family in vertebrates: from the viewpoint of evolutionary genomics
    • Niimura, Y. (2012). Olfactory receptor multigene family in vertebrates: from the viewpoint of evolutionary genomics. Curr. Genomics 13, 103-114. doi: 10.2174/138920212799860706
    • (2012) Curr. Genomics , vol.13 , pp. 103-114
    • Niimura, Y.1
  • 30
    • 17844373261 scopus 로고    scopus 로고
    • Evolutionary dynamics of olfactory receptor genes in fishes and tetrapods
    • Niimura, Y., and Nei, M. (2005). Evolutionary dynamics of olfactory receptor genes in fishes and tetrapods. Proc. Natl. Acad. Sci. U.S.A. 102, 6039-6044. doi: 10.1073/pnas.0501922102
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 6039-6044
    • Niimura, Y.1    Nei, M.2
  • 31
    • 84885040878 scopus 로고    scopus 로고
    • Coelacanth genomes reveal signatures for evolutionary transition from water to land
    • Nikaido, M., Noguchi, H., Nishihara, H., Toyoda, A., Suzuki, Y., Kajitani, R., et al. (2013). Coelacanth genomes reveal signatures for evolutionary transition from water to land. Genome Res. 23, 1740-1748. doi: 10.1101/gr.158105.113
    • (2013) Genome Res , vol.23 , pp. 1740-1748
    • Nikaido, M.1    Noguchi, H.2    Nishihara, H.3    Toyoda, A.4    Suzuki, Y.5    Kajitani, R.6
  • 32
    • 85028023461 scopus 로고    scopus 로고
    • 'Antipredatory defensive roles of natural products from marine invertebrates'
    • eds E. Fattorusso, W. H. Gerwick, and O. Taglialatela-Scarfati (New York, NY: Springer)
    • Pawlik, J. R. (2012). "Antipredatory defensive roles of natural products from marine invertebrates, " in Handbook of Marine Natural Products, eds E. Fattorusso, W. H. Gerwick, and O. Taglialatela-Scarfati (New York, NY: Springer), 677-710. doi: 10.1007/978-90-481-3834-0_12
    • (2012) Handbook of Marine Natural Products , pp. 677-710
    • Pawlik, J.R.1
  • 34
    • 0344301061 scopus 로고
    • Structurally similar natural products in phylogenetically distant marine organisms, and a comparison with terrestrial species
    • Pietra, F. (1995). Structurally similar natural products in phylogenetically distant marine organisms, and a comparison with terrestrial species. Chem. Soc. Rev. 24, 65-71. doi: 10.1039/cs9952400065
    • (1995) Chem. Soc. Rev , vol.24 , pp. 65-71
    • Pietra, F.1
  • 35
    • 33947313652 scopus 로고    scopus 로고
    • Chemical cues, defence metabolites and the shaping of pelagic interspecific interactions
    • Pohnert, G., Steinke, M., and Tollrian, R. (2007). Chemical cues, defence metabolites and the shaping of pelagic interspecific interactions. TREE 22, 198-204. doi: 10.1016/j.tree.2007.01.005
    • (2007) TREE , vol.22 , pp. 198-204
    • Pohnert, G.1    Steinke, M.2    Tollrian, R.3
  • 37
    • 42549164169 scopus 로고    scopus 로고
    • Insect olfactory receptors are heteromeric ligand-gated ion channels
    • Sato, K., Pellegrino, M., Nakagawa, T., Nakagawa, T., Vosshall, L. B., and Touhara, K. (2008). Insect olfactory receptors are heteromeric ligand-gated ion channels. Nature 452, 1002-1006. doi: 10.1038/nature06850
    • (2008) Nature , vol.452 , pp. 1002-1006
    • Sato, K.1    Pellegrino, M.2    Nakagawa, T.3    Nakagawa, T.4    Vosshall, L.B.5    Touhara, K.6
  • 38
    • 84896503906 scopus 로고    scopus 로고
    • Evidence that dimethyl sulfide facilitates a tritrophic mutualism between primary producers and top predators
    • Savoca, M. S., and Nevitt, G. A. (2014). Evidence that dimethyl sulfide facilitates a tritrophic mutualism between primary producers and top predators. Proc. Natl. Acad. Sci. U.S.A. 111, 4157-4161. doi: 10.1073/pnas.1317120111
    • (2014) Proc. Natl. Acad. Sci. U.S.A , vol.111 , pp. 4157-4161
    • Savoca, M.S.1    Nevitt, G.A.2
  • 39
    • 65449179899 scopus 로고    scopus 로고
    • Extraordinary diversity of chemosensory receptor gene repertoires among vertebrates
    • Shi, P., and Zhang, J. (2009). Extraordinary diversity of chemosensory receptor gene repertoires among vertebrates. Results Probl. Cell Differ. 47, 1-23. doi: 10.1007/400_2008_4
    • (2009) Results Probl. Cell Differ , vol.47 , pp. 1-23
    • Shi, P.1    Zhang, J.2
  • 42
    • 77955490196 scopus 로고    scopus 로고
    • The Amphimedon queenslandica genome and the evolution of animal complexity
    • Srivastava, M., Simakov, O., Chapman, J., Fahey, B., Gauthier, M. E. A., Mitros, T., et al. (2010). The Amphimedon queenslandica genome and the evolution of animal complexity. Nature 466, 720-727. doi: 10.1038/nature09201
    • (2010) Nature , vol.466 , pp. 720-727
    • Srivastava, M.1    Simakov, O.2    Chapman, J.3    Fahey, B.4    Gauthier, M.E.A.5    Mitros, T.6
  • 43
    • 65949108430 scopus 로고    scopus 로고
    • Sensing odorants and pheromones with chemosensory receptors
    • Touhara, K., and Vosshall, L. B. (2009). Sensing odorants and pheromones with chemosensory receptors. Annu. Rev. Physiol. 71, 307-332. doi: 10.1146/annurev.physiol.010908.163209
    • (2009) Annu. Rev. Physiol , vol.71 , pp. 307-332
    • Touhara, K.1    Vosshall, L.B.2
  • 44
    • 0034890838 scopus 로고    scopus 로고
    • Chemical composition and behavioural responses of the marine insect Halobates hawaiiensis (Heteroptera: Gerridae)
    • Tsoukatou, M., Cheng, L., Vagias, C., and Roussis, V. (2001). Chemical composition and behavioural responses of the marine insect Halobates hawaiiensis (Heteroptera: Gerridae). Z. Naturforsch. 56c, 597-602.
    • (2001) Z. Naturforsch , vol.56C , pp. 597-602
    • Tsoukatou, M.1    Cheng, L.2    Vagias, C.3    Roussis, V.4
  • 45
    • 84900556152 scopus 로고    scopus 로고
    • Morphology and histochemistry of the aesthetasc-associated epidermal glands in terrestrial hermit crabs of the genus Coenobita (Decapoda: Paguroidea)
    • Tuchina, O., Groh, K. C., Talarico, G., Muller, C. H. G., Wielsch, N., Hupfer, Y., et al. (2014). Morphology and histochemistry of the aesthetasc-associated epidermal glands in terrestrial hermit crabs of the genus Coenobita (Decapoda: Paguroidea). PLoS ONE 9:e96430. doi: 10.1371/journal.pone.0096430
    • (2014) PLoS ONE , vol.9
    • Tuchina, O.1    Groh, K.C.2    Talarico, G.3    Muller, C.H.G.4    Wielsch, N.5    Hupfer, Y.6
  • 46
    • 42549118499 scopus 로고    scopus 로고
    • Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels
    • Wicher, D., Schäfer, R., Bauernfeind, R., Stensmyr, M. C., Heller, R., Heinemann, S. H., et al. (2008). Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels. Nature 452, 1007-1011. doi: 10.1038/nature06861
    • (2008) Nature , vol.452 , pp. 1007-1011
    • Wicher, D.1    Schäfer, R.2    Bauernfeind, R.3    Stensmyr, M.C.4    Heller, R.5    Heinemann, S.H.6
  • 47
    • 84893717619 scopus 로고    scopus 로고
    • Furanodiene presents synergistic anti-proliferative activity with paclitaxel via altering cell cycle and integrin signaling in 95-D lung cancer cells
    • Xu, W. S., Dang, Y. Y., Chen, X. P., Lu, J. J., and Wang, Y. T. (2014). Furanodiene presents synergistic anti-proliferative activity with paclitaxel via altering cell cycle and integrin signaling in 95-D lung cancer cells. Phytother. Res. 28, 296-299. doi: 10.1002/ptr.4984
    • (2014) Phytother. Res , vol.28 , pp. 296-299
    • Xu, W.S.1    Dang, Y.Y.2    Chen, X.P.3    Lu, J.J.4    Wang, Y.T.5
  • 48
    • 84864402186 scopus 로고    scopus 로고
    • Furanodiene, a natural product, inhibits breast cancer growth both in vitro and in vivo
    • Zhong, Z., Dang, Y., Yuan, X., Guo, W., Li, Y., Tan, W., et al. (2012a). Furanodiene, a natural product, inhibits breast cancer growth both in vitro and in vivo. Cell. Physiol. Biochem. 30, 778-790. doi: 10.1159/000341457
    • (2012) Cell. Physiol. Biochem , vol.30 , pp. 778-790
    • Zhong, Z.1    Dang, Y.2    Yuan, X.3    Guo, W.4    Li, Y.5    Tan, W.6
  • 49
    • 84861185541 scopus 로고    scopus 로고
    • Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo
    • Zhong, Z. F., Hoi, P. M., Wu, G. S., Xu, Z. T., Tan, W., Chen, X. P., et al. (2012b). Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo. J. Ethnopharmacol. 141, 721-727. doi: 10.1016/j.jep.2011.08.052
    • (2012) J. Ethnopharmacol , vol.141 , pp. 721-727
    • Zhong, Z.F.1    Hoi, P.M.2    Wu, G.S.3    Xu, Z.T.4    Tan, W.5    Chen, X.P.6
  • 50
    • 84862546181 scopus 로고    scopus 로고
    • Furanodiene enhances tamoxifen-induced growth inhibitory activity of ERa-positive breast cancer cells in a PPAR?. independent manner
    • Zhong, Z. F., Li, Y. B., Wang, S. P., Tan, W., Chen, X. P., Chen, M. W., et al. (2012c). Furanodiene enhances tamoxifen-induced growth inhibitory activity of ERa-positive breast cancer cells in a PPAR? independent manner. J. Cell. Biochem. 113, 2643-2651. doi: 10.1002/jcb.24139
    • (2012) J. Cell. Biochem , vol.113 , pp. 2643-2651
    • Zhong, Z.F.1    Li, Y.B.2    Wang, S.P.3    Tan, W.4    Chen, X.P.5    Chen, M.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.