Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors

Acta Neuropathologica

Volumn 131, Issue 3, 2016, Pages 365-378

  Brandenburg, Susan ^a   Müller, Annett ^a   Turkowski, Kati ^a   Radev, Yordan T ^a   Rot, Sergej ^a   Schmidt, Christin ^a   Bungert, Alexander D ^a   Acker, Güliz ^a   Schorr, Anne ^b   Hippe, Andreas ^b   Miller, Kelly ^a   Heppner, Frank L ^a   Homey, Bernhard ^b   Vajkoczy, Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

Angiogenic molecules; CXCL2; Glioblastoma multiforme; Microglia macrophages; Tumor angiogenesis

Indexed keywords

ANGIOGENIC FACTOR; CD11B ANTIGEN; CHEMOKINE RECEPTOR CXCR2; CXCL2 CHEMOKINE; VASCULOTROPIN; CXCL2 PROTEIN, MOUSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL DENSITY; CHIMERA; ENDOTHELIUM CELL; GLIOBLASTOMA; IN VITRO STUDY; MACROPHAGE; MICROGLIA; MOUSE; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIPHERAL MACROPHAGE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESIDENT MICROGLIA; STEREOTACTIC PROCEDURE; T CELL DEPLETION; TUMOR VASCULARIZATION; TUMOR VOLUME; UPREGULATION; VASCULAR REMODELING; VASCULAR TUMOR; ANIMAL; BRAIN TUMOR; C57BL MOUSE; DISEASE MODEL; GLIOMA; IMMUNOHISTOCHEMISTRY; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; BRAIN NEOPLASMS; CHEMOKINE CXCL2; DISEASE MODELS, ANIMAL; GLIOMA; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; NEOVASCULARIZATION, PATHOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84958125517     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-015-1529-6     Document Type: Article

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