Restoring placental growth factor-soluble fms-like tyrosine kinase-1 balance reverses vascular hyper-reactivity and hypertension in pregnancy

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 311, Issue 3, 2016, Pages R505-R521

  Zhu, Minglin ^a   Ren, Zongli ^a   Possomato Vieira, José S ^a   Khalil, Raouf A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Angiogenesis; Calcium; Endothelium; Hypertension; Nitric oxide; Preeclampsia; Vascular smooth muscle

Indexed keywords

CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR RECEPTOR 1; PHENYLEPHRINE; PLACENTAL GROWTH FACTOR; POTASSIUM CHLORIDE; VASCULOTROPIN; FLT1 PROTEIN, RAT; PGF PROTEIN, RAT; VASCULOTROPIN RECEPTOR 1;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL FUNCTION; BLOOD VESSEL REACTIVITY; CAROTID ARTERY; CONTROLLED STUDY; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GESTATIONAL AGE; KIDNEY ARTERY; MATERNAL HYPERTENSION; MESENTERIC ARTERY; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PERFUSION PRESSURE; PLACENTA CIRCULATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SIGNAL TRANSDUCTION; VASOCONSTRICTION; VASODILATATION; VENOCONSTRICTION; ADRENERGIC SYSTEM; ANIMAL; HYPERTENSION; METABOLISM; PATHOPHYSIOLOGY; PREGNANCY; PREGNANCY COMPLICATION; SPRAGUE DAWLEY RAT;

ANIMALS; BLOOD PRESSURE; FEMALE; HYPERTENSION; PLACENTA GROWTH FACTOR; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1; VASOMOTOR SYSTEM;

EID: 84986537489     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00137.2016     Document Type: Article

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