Enhanced [Ca2+]i in renal arterial smooth muscle cells of pregnant rats with reduced uterine perfusion pressure

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 1 53-1, 2003, Pages

  Murphy, Jason G ^a   Herrington, Jason N ^a   Granger, Joey P ^a   Khalil, Raouf A ^b  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Calcium; Contraction; Hypertension; Vascular resistance; Vascular smooth muscle

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ANGIOTENSIN; CAFFEINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL STIMULATING AGENT; CALCIUM ION; DILTIAZEM; EGTAZIC ACID; NICKEL CHLORIDE; POTASSIUM CHLORIDE; ANGIOTENSIN II; CALCIUM; CULTURE MEDIUM;

ANIMAL CELL; ARTICLE; BLOOD PRESSURE; CALCIUM CELL LEVEL; CONTROLLED STUDY; FEMALE; HYPERTENSION; KIDNEY ARTERY; NONHUMAN; PERFUSION PRESSURE; PREGNANCY; PRIORITY JOURNAL; RAT; UTERUS BLOOD FLOW; VASCULAR RESISTANCE; VASCULAR SMOOTH MUSCLE; ANIMAL; BLOOD FLOW; BREEDING; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECTS; INTRACELLULAR MEMBRANE; METABOLISM; OSMOLARITY; PHYSIOLOGY; UTERUS; VASCULARIZATION; VASOCONSTRICTION; DRUG EFFECT; RENAL ARTERY;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; CALCIUM; CALCIUM CHANNEL AGONISTS; CULTURE MEDIA; FEMALE; INTRACELLULAR MEMBRANES; MUSCLE, SMOOTH, VASCULAR; OSMOLAR CONCENTRATION; POTASSIUM CHLORIDE; PREGNANCY; PREGNANCY, ANIMAL; RATS; REGIONAL BLOOD FLOW; RENAL ARTERY; UTERUS; VASOCONSTRICTION;

EID: 0037235250     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00247.2002     Document Type: Article

References (63)

1. Abram SR, Alexander BT, Bennett WA, and Granger JP. Role of neuronal nitric oxide synthase in mediating renal hemodynamic changes during pregnancy. Am J Physiol Regul Integr Comp Physiol 281: R1390-R1393, 2001.
2. Alexander BT, Cockrell KL, Massey MB, Bennett WA, and Granger JP. Tumor necrosis factor-α-induced hypertension in pregnant rats results in decreased renal neuronal nitric oxide synthase expression. Am J Hypertens 15: 170-175, 2002.
3. Alexander BT, Kassab SE, Miller MT, Abram SR, Reckelhoff JF, Bennett WA, and Granger JP. Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide. Hypertension 37: 1191-1195, 2001.
4. Alexander BT, Miller MT, Kassab S, Novak J, Reckelhoff JF, Kruckeberg WC, and Granger JP. Differential expression of renal nitric oxide synthase isoforms during pregnancy in rats. Hypertension 33: 435-439, 1999.
5. Alexander RW, Brock TA, Gimbrone MA Jr, and Rittenhouse SE. Angiotensin increases inositol trisphosphate and calcium in vascular smooth muscle. Hypertension 7: 447-451, 1985.
6. Amrani Y, Martinet N, and Bronner C. Potentiation by tumour necrosis factor-α of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells. Br J Pharmacol 114: 4-5, 1995.
7. Baylis C, Suto T, and Conrad K. Importance of nitric oxide in control of systemic and renal hemodynamics during normal pregnancy: Studies in the rat and implications for preeclampsia. Hypertens Preg 15: 147-169, 1996.
8. Baylis C. The determinants of renal hemodynamics in pregnancy. Am J Kidney Dis 9: 260-264, 1987.
9. Berridge MJ and Irvine RF. Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature 312: 315-321, 1984.
10. Brock TA, Alexander RW, Ekstein LS, Atkinson WJ, and Gimbrone MA Jr. Angiotensin increases cytosolic free calcium in cultured vascular smooth muscle cells. Hypertension 7: 1105-11109, 1985.
11. Chapman AB, Abraham WT, Zamudio S, Coffin C, Merouani A, Young D, Johnson A, Osorio F, Goldberg C, Moore LG, Dahms T, and Schrier RW. Temporal relationships between hormonal and hemodynamic changes in early human pregnancy. Kidney Int 54: 2056-2063, 1998.
12. Conrad KP and Vernier KA. Plasma levels, urinary excretion and metabolic production of cGMP during gestation in rats. Am J Physiol Regul Integr Comp Physiol 257: R847-R853, 1989.
13. Conrad KP, Joffe GM, Kruszyna H, Kruszyna R, Rochelle LG, Smith RP, Chavez JE, and Mosher MD. Identification of increased nitric oxide biosynthesis during pregnancy in rats. FASEB J 7: 566-571, 1993.
14. Conrad KP, Miles TM, and Benyo DF. Circulating levels of immunoreactive cytokines in women with preeclampsia. Am J Reprod Immunol 40: 102-111, 1998.
15. Conrad KP. Animal models of pre-eclampsia: Do they exist? Fetal Med Rev 2: 67-88, 1990.
16. Conrad KP. Possible mechanisms for changes in renal hemodynamics during pregnancy: Studies from animal models. Am J Kidney Dis 9: 253-259, 1987.
17. Crews JK, Herrington JN, Granger JP, and Khalil RA. Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat. Hypertension 35: 367-372, 2000.
18. Davis JR, Giardina JB, Green GM, Alexander BT, Granger JP, and Khalil RA. Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-α-induced hypertension in pregnant rats. Am J Physiol Regul Integr Comp Physiol 282: R390-R399, 2002.
19. Duvekot JJ and Peeters LL. Renal hemodynamics and volume homeostasis in pregnancy. Obstet Gynecol Surv 49: 830-839, 1994.
20. Eder DJ and McDonald MT. A role for brain angiotensin II in experimental pregnancy-induced hypertension in laboratory rats. Clin Exp Hyper Hyper Preg B6: 431-451, 1987.
21. Friedman SA, Lubarsky SL, Ahokas RA, Nova A, and Sibai BM. Preeclampsia and related disorders. Clinical aspects and relevance of endothelin and nitric oxide. Clin Perinatol 22: 343-355, 1995.
22. Granger JP, Alexander BT, Bennett WA, and Khalil RA. Pathophysiology of pregnancy-induced hypertension. Am J Hypertens 14: 178S-185S, 2001.
23. Greer IA, Lyall F, Perera T, Boswell F, and Macara LM. Increased concentrations of cytokines interleukin-6 and interleukin-1 receptor antagonist in plasma of women with preeclampsia: A mechanism for endothelial dysfunction? Obstet Gynecol 84: 937-940, 1994.
24. Griendling KK, Rittenhouse SE, Brock TA, Ekstein LS, Gimbrone MA Jr, and Alexander RW. Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells. J Biol Chem 261: 5901-5906, 1986.
25. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
26. Horowitz A, Menice CB, Laporte R, and Morgan KG. Mechanisms of smooth muscle contraction. Physiol Rev 76: 967-1003, 1996.
27. Kanashiro CA and Khalil RA. Signal transduction by protein kinase C in mammalian cells. Clin Exp Pharmacol Physiol 25: 974-985, 1998.
28. Khalil RA, Crews JK, Novak J, Kassab S, and Granger JP. Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats. Hypertension 31: 1065-1069, 1998.
29. i threshold for translocation of the a-protein kinase C isoform. Am J Physiol Cell Physiol 266: C1544-C1551, 1994.
30. Khalil RA and Morgan KG. Phenylephrine-induced translocation of protein kinase C and shortening of two types of vascular cells of the ferret. J Physiol 455: 585-599, 1992.
31. Khalil RA and van Breemen C. Mechanisms of calcium mobilization and homeostasis in vascular smooth muscle and their relevance to hypertension. In: Hypertension: Pathophysiology, Diagnosis, and Management, edited by Laragh JH and Brenner BM. New York: Raven, 1995, p. 523-540.
32. Khalil RA and van Breemen C. Sustained contraction of vascular smooth muscle: Calcium influx or C-kinase activation? J Pharmacol Exp Ther 244: 537-542, 1988.
33. Kupferminc MJ, Peaceman AM, Wigton TR, Rehnberg KA, and Socol ML. Tumor necrosis factor-a is elevated in plasma and amniotic fluid of patients with severe preeclampsia. Am J Obstet Gynecol 170: 1752-1759, 1994.
34. Leijten PA and van Breemen C. The effects of caffeine on the noradrenaline-sensitive calcium store in rabbit aorta. J Physiol 357: 327-339, 1984.
35. Lindheimer MD and Katz AI. Hypertension in pregnancy. N Engl J Med 313: 675-680, 1985.
36. Lindheimer MD and Katz AI. Preeclampsia: Pathophysiology, diagnosis, and management. Annu Rev Med 40: 233-250, 1989.
37. Liu H, Xiong Z, and Sperelakis N. Cyclic nucleotides regulate the activity of L-type calcium channels in smooth muscle cells from rat portal vein. J Mol Cell Cardiol 29: 1411-1421, 1997.
38. Losonczy G, Brown G, and Venuto RC. Increased peripheral resistance during reduced uterine perfusion pressure hypertension in pregnant rabbits. Am J Med Sci 303: 233-240, 1992.
39. 2+ entry. Circ Res 87:551-557, 2000.
40. ω-nitro-L-arginine, an inhibitor of nitric oxide synthesis, increases blood pressure in rats and reverses the pregnancy induced refractoriness to vasopressor agents. Am J Obstet Gynecol 166: 1560-1567, 1992.
41. Morris NH, Eaton BM, and Dekker G. Nitric oxide, the endothelium, pregnancy and pre-eclampsia. Br J Obstet Gynaecol 103: 4-15, 1996.
42. i signaling in renal arterial smooth muscle cells of pregnant rat is enhanced during inhibition of NOS. Am J Physiol Regul Integr Comp Physiol 280: R87-R99, 2001.
43. i in vascular smooth muscle cells of female rat. Am J Physiol Cell Physiol 278: C834-C844, 2000.
44. Nathan L, Cuevas J, and Chaudhuri G. The role of nitric oxide in the altered vascular reactivity of pregnancy in the rat. Br J Pharmacol 114: 955-960, 1995.
45. Nayler WG, Perry SE, Elz JS, and Daly MJ. Calcium, sodium, and the calcium paradox. Circ Res 55: 227-237, 1984.
46. Nelson SH, Steinsland OS, Wang Y, Yallampalli C, Dong YL, and Sanchez JM. Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancy. Circ Res 87: 406-411, 2000.
47. Nienartowicz A, Link S, and Moll W. Adaptation of the uterine arcade in rats to pregnancy. J Dev Physiol 12: 101-108, 1989.
48. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258: 607-614, 1992.
49. Parris JR, Cobban HJ, Littlejohn AF, MacEwan DJ, and Nixon GF. Tumour necrosis factor-α activates a calcium sensitization pathway in guinea-pig bronchial smooth muscle. J Physiol 518: 561-569, 1999.
50. Podjarny E, Baylis C, and Losonczy G. Animal models of preeclampsia. Semin Perinatol 23: 2-13, 1999.
51. Probst BD. Hypertensive disorders of pregnancy. Emerg Med Clin North Am 12: 73-89, 1994.
52. 2+ channels by cyclic nucleotide cross activation of opposing protein kinases in rabbit portal vein. Circ Res 82: 557-565, 1998.
53. Sabri A, Govindarajan G, Griffin TM, Byron KL, Samarel AM, and Lucchesi PA. Calcium- and protein kinase C-dependent activation of the tyrosine kinase PYK2 by angiotensin II in vascular smooth muscle. Circ Res 83: 841-851, 1998.
54. Schroeder AC, Imig JD, LeBlanc EA, Pham BT, Pollock DM, and Inscho EW. Endothelin-mediated calcium signaling in preglomerular smooth muscle cells. Hypertension 35: 280-286, 2000.
55. 2+-channel current in vascular smooth muscle cells is inhibited by lavendustin-A and LY-294002. Pflügers Arch 437: 317-323, 1999.
56. Sladek SM, Magness RR, and Conrad KP. Nitric oxide and pregnancy. Am J Physiol Regul Integr Comp Physiol 272: R441-R463, 1997.
57. Somlyo AP, Wu X, Walker LA, and Somlyo AV. Pharmacomechanical coupling: The role of calcium, G-proteins, kinases and phosphatases. Rev Physiol Biochem Pharmacol 134: 201-234, 1999.
58. Sowers JR, Zemel MB, Walsh MF, Standley PR, Zemel PC, Bronsteen RA, Kraniak J, and Sokol RJ. Effects of normal pregnancy on cellular cation metabolism and peripheral vascular resistance. Am J Hypertens 3: 16-22, 1990.
59. 2+ from intracellular store sites in skinned single cells of porcine coronary artery. Biochem Biophys Res Commun 120: 481-485, 1984.
60. Taguchi K, Ueda M, and Kubo T. Effects of cAMP and cGMP on L-type calcium channel currents in rat mesenteric artery cells. Jpn J Pharmacol 74: 179-186, 1997.
61. Vince GS, Starkey PM, Austgulen R, Kwiatkowski D, and Redman CW. Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia. Br J Obstet Gynaecol 102: 20-25, 1995.
62. Williams DA, Becker PL, and Fay FS. Regional changes in calcium underlying contraction of single smooth muscle cells. Science 235: 1644-1648, 1987.
63. Williams MA, Mahomed K, Farrand A, Woelk GB, Mudzamiri S, Madzime S, King IB, and McDonald GB. Plasma tumor necrosis factor-α soluble receptor p55 (sTNFp55) concentrations in eclamptic, preeclamptic and normotensive pregnant Zimbabwean women. J Reprod Immunol 40: 159-173, 1998.