Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans

Aging Cell

Volumn 15, Issue 5, 2016, Pages 903-913

  Lee, Benjamin P ^a   Pilling, Luke C ^b   Emond, Florence ^a   Flurkey, Kevin ^c   Harrison, David E ^c   Yuan, Rong ^c,f   Peters, Luanne L ^c   Kuchel, George A ^d   Ferrucci, Luigi ^e   Melzer, David ^b,d   Harries, Lorna W ^a  

^a RNA Mediated Mechanisms of Disease   (United Kingdom)

^b UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^c JACKSON LABORATORY   (United States)

^d UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

isoforms; lifespan; longevity; mouse; mRNA splicing; splicing factors

Indexed keywords

ALTERNATIVE RNA SPLICING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC REGULATION; GENETIC VARIATION; HUMAN; HUMAN CELL; LIFESPAN; LONGEVITY; MOUSE; MUSCLE TISSUE; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; SENESCENCE; SPLEEN; SPLENIC TISSUE; SPLICEOSOME; STRAIN DIFFERENCE;

EID: 84986203616     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12499     Document Type: Article

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