Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

eLife

Volumn 5, Issue Se, 2016, Pages

  Harrison, Joseph S ^a,b   Cornett, Evan M ^c   Goldfarb, Dennis ^d   Darosa, Paul A ^e   Li, Zimeng M ^f   Yan, Feng ^a   Dickson, Bradley M ^c   Guo, Angela H ^a   Cantu, Daniel V ^a   Kaustov, Lilia ^g   Brown, Peter J ^g   Arrowsmith, Cheryl H ^g   Erie, Dorothy A ^f   Major, Michael B ^a,d   Klevit, Rachel E ^e   Krajewski, Krzysztof ^a   Kuhlman, Brian ^a,b   Strahl, Brian D ^a,b   Rothbart, Scott B ^c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c VAN ANDEL RESEARCH INSTITUTE   (United States)

^d CB 3175 Sitterson Hall   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f University of North Carolina at Chapel Hill   (United States)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; UBIQUITIN PROTEIN LIGASE; UHRF1 PROTEIN; UNCLASSIFIED DRUG; CCAAT ENHANCER BINDING PROTEIN; DNA; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; HISTONE; PROTEIN BINDING; UHRF1 PROTEIN, HUMAN;

ALLOSTERISM; ANISOTROPY; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; DNA BINDING; DNA METHYLATION; ENZYME ACTIVITY; FLUORESCENCE POLARIZATION; HISTONE UBIQUITINATION; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION CALORIMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOTON CORRELATION SPECTROSCOPY; PROTEIN SYNTHESIS; SIZE EXCLUSION CHROMATOGRAPHY; GENETIC EPIGENESIS; HELA CELL LINE; JURISPRUDENCE; METABOLISM; UBIQUITINATION;

CCAAT-ENHANCER-BINDING PROTEINS; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENESIS, GENETIC; HELA CELLS; HISTONES; HUMANS; PROTEIN BINDING; UBIQUITINATION; WILLS;

EID: 84986203552     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.17101     Document Type: Article

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