Expression of AE1/p16 promoted degradation of AE2 in gastric cancer cells

BMC Cancer

Volumn 16, Issue 1, 2016, Pages

  Wang, Ting ^a   Fei, Hong Jun ^a   Yang, Ye ^b   Jiang, Xiao Shu ^c   Yan, Min ^a   Zeng, Zhi ^a   Wu, Jun ^a   Song, Ling Jun ^a   Tian, Hua ^a   Fu, Guo Hui ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NINGBO NO 2 HOSPITAL   (China)

^c HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

AE1; AE2; Gastric cancer; Gastrin; P16

Indexed keywords

ANION EXCHANGER 1 PROTEIN; ANION EXCHANGER 2 PROTEIN; ANTIPORTER; GASTRIN; PROTEIN P16; UNCLASSIFIED DRUG; BICARBONATE CHLORIDE ANTIPORTER; CYCLIN DEPENDENT KINASE INHIBITOR 2A; ERYTHROCYTE BAND 3 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CANCER GROWTH; CANCER PROGNOSIS; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PH; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STOMACH CANCER; STOMACH CARCINOGENESIS; ANIMAL; BAGG ALBINO MOUSE; DRUG SCREENING; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; METABOLISM; NUDE MOUSE; STOMACH TUMOR; TUMOR CELL LINE;

ANIMALS; ANION EXCHANGE PROTEIN 1, ERYTHROCYTE; CELL LINE, TUMOR; CHLORIDE-BICARBONATE ANTIPORTERS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GASTRINS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; MICE, INBRED BALB C; MICE, NUDE; STOMACH NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84985020849     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-016-2751-x     Document Type: Article

References (34)

1. Niccolai E, Taddei A, Prisco D, Amedei A. Gastric cancer and the epoch of immunotherapy approaches. World J Gastroenterol. 2015;21:5778-93.
2. Qiu MZ, Cai MY, Zhang DS, Wang ZQ, Wang DS, Li YH, et al. Clinicopathological characteristics and prognostic analysis of Lauren classification in gastric adenocarcinoma in China. J Transl Med. 2013;11:58.
3. Dicken BJ, Bigam DL, Cass C, Mackey JR, Joy AA, Hamilton SM. Gastric adenocarcinoma: review and considerations for future directions. Ann Surg. 2005;241:27-39.
4. Dinis-Ribeiro M, Areia M, de Vries AC, Marcos-Pinto R, Monteiro-Soares M, O'Connor A, et al. Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Pathology (ESP), and the Sociedade Portuguesa de Endoscopia Digestiva (SPED). Endoscopy. 2012;44:74-94.
5. Vannella L, Lahner E, Annibale B. Risk for gastric neoplasias in patients with chronic atrophic gastritis: a critical reappraisal. World J Gastroenterol. 2012;18:1279-85.
6. Cheng AS, Li MS, Kang W, Cheng VY, Chou JL, Lau SS, et al. Helicobacter pylori causes epigenetic dysregulation of FOXD3 to promote gastric carcinogenesis. Gastroenterology. 2013;144:122-33. e129.
7. Alper SL. Molecular physiology and genetics of Na + -independent SLC4 anion exchangers. J Exp Biol. 2009;212:1672-83.
8. Kodippili GC, Spector J, Hale J, Giger K, Hughes MR, McNagny KM, et al. Analysis of the mobilities of band 3 populations associated with ankyrin protein and junctional complexes in intact murine erythrocytes. J Biol Chem. 2012;287:4129-38.
9. Yamaguchi T, Ikeda Y, Abe Y, Kuma H, Kang D, Hamasaki N, et al. Structure of the membrane domain of human erythrocyte anion exchanger 1 revealed by electron crystallography. J Mol Biol. 2010;397:179-89.
10. Alper SL, Chernova MN, Stewart AK. How pH regulates a pH regulator: a regulatory hot spot in the N-terminal cytoplasmic domain of the AE2 anion exchanger. Cell Biochem Biophys. 2002;36:123-36.
11. Stewart AK, Kurschat CE, Vaughan-Jones RD, Alper SL. Putative Re-entrant Loop 1 of AE2 Transmembrane Domain Has a Major Role in Acute Regulation of Anion Exchange by pH. J Biol Chem. 2009;284:6126-39.
12. Reimold FR, Stewart AK, Stolpe K, Heneghan JF, Shmukler BE, Alper SL. Substitution of transmembrane domain Cys residues alters pH(o)-sensitive anion transport by AE2/SLC4A2 anion exchanger. Pflugers Arch - Eur J Physiol. 2013;465:839-51.
13. Kopic S, Murek M, Geibel JP. Revisiting the parietal cell. Am J Physiol Cell Physiol. 2010;298:C1-C10.
14. Kosiek O, Busque SM, Foller M, Shcheynikov N, Kirchhoff P, Bleich M, et al. SLC26A7 Can function as a chloride-loading mechanism in parietal cells. Pflugers Arch - Eur J Physiol. 2007;454:989-98.
15. Gawenis LR, Ledoussal C, Judd LM, Prasad V, Alper SL, Stuart-Tilley A, et al. Mice with a targeted disruption of the AE2 Cl-/HCO3- exchanger are achlorhydric. J Biol Chem. 2004;279:30531-9.
16. Recalde S, Muruzabal F, Looije N, Kunne C, Burrell MA, Saez E, et al. Inefficient chronic activation of parietal cells in Ae2(a, b)(-/-) mice. Am J Pathol. 2006;169:165-76.
17. Fu GH, Wang Y, Xi YH, Shen WW, Pan XY, Shen WZ, et al. Direct interaction and cooperative role of tumor suppressor p16 with band 3 (AE1). FEBS Lett. 2005;579:2105-10.
18. Wang Y, Wu SF, Chen GQ, Fu GH. Effect of block deletions in the C-terminus on the functional expression of human anion exchanger 1 (AE1). Mol Membr Biol. 2007;24:65-73.
19. Shen WW, Wu J, Cai L, Liu BY, Gao Y, Chen GQ, et al. Expression of anion exchanger 1 sequestrates p16 in the cytoplasm in gastric and colonic adenocarcinoma. Neoplasia. 2007;9:812-9.
20. Liu Q, Song LJ, Xu WQ, Zhao L, Zheng L, Yan ZW, et al. Expression of cytoplasmic p16 and anion exchanger 1 is associated with the invasion and absence of lymph metastasis in gastric carcinoma. Mol Med Rep. 2009;2:169-74.
21. Xu WQ, Song LJ, Liu Q, Zhao L, Zheng L, Yan ZW, et al. Expression of anion exchanger 1 is associated with tumor progress in human gastric cancer. J Cancer Res Clin Oncol. 2009;135:1323-30.
22. Suo WH, Zhang N, Wu PP, Zhao L, Song LJ, Shen WW, et al. Anti-tumour effects of small interfering RNA targeting anion exchanger 1 in experimental gastric cancer. Br J Pharmacol. 2012;165:135-47.
23. Alper SL. The band 3-related anion exchanger (AE) gene family. Annu Rev Physiol. 1991;53:549-64.
24. Wu J, Zhang YC, Suo WH, Liu XB, Shen WW, Tian H, et al. Induction of anion exchanger-1 translation and its opposite roles in the carcinogenesis of gastric cancer cells and differentiation of K562 cells. Oncogene. 2010;29:1987-96.
25. Tian H, Zhang N, Suo WH, Wang T, Song LJ, Wu J, et al. Gastrin suppresses the interdependent expression of p16 and anion exchanger 1 favoring growth inhibition of gastric cancer cells. Int J Cancer. 2010;127:1462-74.
26. Lauritzen G, Jensen MBF, Boedtkjer E, Dybboe R, Aalkjaer C, Nylandsted J, et al. NBCn1 and NHE1 expression and activity in Delta NErbB2 receptor-expressing MCF-7 breast cancer cells: Contributions to pH(i) regulation and chemotherapy resistance. Exp Cell Res. 2010;316:2538-53.
27. Lauritzen G, Stock CM, Lemaire J, Lund SF, Jensen MF, Damsgaard B, et al. The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2. Cancer Lett. 2012;317:172-83.
28. Su Y, Blake-Palmer KG, Fry AC, Best A, Brown ACN, Hiemstra TF, et al. Glyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidney. Am J Physiol Renal Physiol. 2011;300:F157-66.
29. Patterson ST, Reithmeier RA. Cell surface rescue of kidney anion exchanger 1 mutants by disruption of chaperone interactions. J Biol Chem. 2010;285(43):33423-34.
30. Zhang ZR, Bonifacino JS, Hegde RS. Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER. Cell. 2013;154(3):609-22.
31. Reshkin SJ, Cardone RA, Harguindey S. Na + -H+ Exchanger, pH Regulation and Cancer. Recent Pat Anticancer Drug Discov. 2013;8:85-99.
32. Wang T, Zhao L, Yang Y, Tian H, Suo WH, Yan M, et al. EGR1 is critical for gastrin-dependent upregulation of anion exchanger 2 in gastric cancer cells. FEBS J. 2013;280:174-83.
33. Cardone RA, Casavola V, Reshkin SJ. The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis. Nat Rev Cancer. 2005;5:786-95.
34. Porporato PE, Dhup S, Dadhich RK, Copetti T, Sonveaux P. Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review. Front Pharmacol. 2011;2:49.