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Volumn 48, Issue 3, 2016, Pages 342-350

The role of AHR-inducible cytochrome P450s in metabolism of polyunsaturated fatty acids

Author keywords

2,3,7,8 Tetrachlorodibenzo dioxin (TCDD); aryl hydrocarbon receptor (AHR); CYP1; eicosanoid; metastasis; omega 3 ( 3) PUFA; omega 6 ( 6) PUFA; oxylipin; polyunsaturated fatty acids (PUFA); tumor growth

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450; DIOL; EPOXIDE; HYDROXYL GROUP; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; OXYLIPIN; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG; CYTOCHROME P450 INDUCER; POLYCHLORINATED DIBENZODIOXIN; UNSATURATED FATTY ACID;

EID: 84984972083     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.1080/03602532.2016.1197240     Document Type: Review
Times cited : (48)

References (40)
  • 1
    • 9344221635 scopus 로고    scopus 로고
    • Dose-response relationship of cytochrome P4501b1 mRNA induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in livers of C57BL/6J and DBA/2J mice
    • J.Abel, W.Li, O.D ṏõhr. (1996). Dose-response relationship of cytochrome P4501b1 mRNA induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in livers of C57BL/6J and DBA/2J mice. Arch Toxicol 70:510–513.
    • (1996) Arch Toxicol , vol.70 , pp. 510-513
    • Abel, J.1    Li, W.2    D ṏõhr, O.3
  • 2
    • 67650074960 scopus 로고    scopus 로고
    • Cytochrome P450 CYP1A1: Wider roles in cancer progression and prevention
    • V.P.Androutsopoulos, A.M.Tsatsakis, D.A.Spandidos (2009). Cytochrome P450 CYP1A1:Wider roles in cancer progression and prevention. BMC Cancer 9:187.
    • (2009) BMC Cancer , vol.9 , pp. 187
    • Androutsopoulos, V.P.1    Tsatsakis, A.M.2    Spandidos, D.A.3
  • 3
    • 84904216760 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor control of a disease tolerance defence pathway
    • A.Bessede, M.Gargaro, M.Pallotta. (2014). Aryl hydrocarbon receptor control of a disease tolerance defence pathway. Nature 511:184–190.
    • (2014) Nature , vol.511 , pp. 184-190
    • Bessede, A.1    Gargaro, M.2    Pallotta, M.3
  • 4
    • 53349100942 scopus 로고    scopus 로고
    • Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: comparison of rat and mouse
    • P.C.Boutros, R.Yan, I.D.Moffatt. (2008). Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver:comparison of rat and mouse. BMC Genomics 9:419.
    • (2008) BMC Genomics , vol.9 , pp. 419
    • Boutros, P.C.1    Yan, R.2    Moffatt, I.D.3
  • 5
    • 67650531422 scopus 로고    scopus 로고
    • Thematic review series: Proteomics. An integrated omics analysis of eicosanoid biology
    • M.W.Buczynski, D.S.Dumlao, E.A.Dennis (2009). Thematic review series:Proteomics. An integrated omics analysis of eicosanoid biology. J Lipid Res 50:1015–1038.
    • (2009) J Lipid Res , vol.50 , pp. 1015-1038
    • Buczynski, M.W.1    Dumlao, D.S.2    Dennis, E.A.3
  • 6
    • 84862786892 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin treatment alters eicosanoid levels in several organs of the mouse in an aryl hydrocarbon receptor-dependent fashion
    • P.Bui, P.Solaimani, X.Wu. (2012). 2,3,7,8-Tetrachlorodibenzo-p-dioxin treatment alters eicosanoid levels in several organs of the mouse in an aryl hydrocarbon receptor-dependent fashion. Toxicol Appl Pharmacol 259:143–151.
    • (2012) Toxicol Appl Pharmacol , vol.259 , pp. 143-151
    • Bui, P.1    Solaimani, P.2    Wu, X.3
  • 7
    • 3242682298 scopus 로고    scopus 로고
    • Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1
    • D.Choudhary, I.Jansson, I.Stoilov. (2004). Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1. Drug Metab Dispos 32:840–847.
    • (2004) Drug Metab Dispos , vol.32 , pp. 840-847
    • Choudhary, D.1    Jansson, I.2    Stoilov, I.3
  • 8
    • 0035748961 scopus 로고    scopus 로고
    • Dioxin exposure is an environmental risk factor for ischemic heart disease
    • T.P.Dalton, J.K.Kerzee, B.Wang. (2001). Dioxin exposure is an environmental risk factor for ischemic heart disease. Cardiovasc Toxicol 1:285–298.
    • (2001) Cardiovasc Toxicol , vol.1 , pp. 285-298
    • Dalton, T.P.1    Kerzee, J.K.2    Wang, B.3
  • 9
    • 84155196846 scopus 로고    scopus 로고
    • Exactly the same but different: Promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor
    • M.S.Denison, A.A.Soshilov, G.He. (2011). Exactly the same but different:Promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicol Sci 124:1–22.
    • (2011) Toxicol Sci , vol.124 , pp. 1-22
    • Denison, M.S.1    Soshilov, A.A.2    He, G.3
  • 10
    • 84891756950 scopus 로고    scopus 로고
    • Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolase inhibitor AUDA
    • S.Diani-Moore, Y.Ma, S.S.Gross. (2014). Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolase inhibitor AUDA. Drug Metabol Dispos 42:294–300.
    • (2014) Drug Metabol Dispos , vol.42 , pp. 294-300
    • Diani-Moore, S.1    Ma, Y.2    Gross, S.S.3
  • 11
    • 84879492780 scopus 로고    scopus 로고
    • Role of aryl hydrocarbon receptor in cancer
    • S.Feng, Z.Cao, X.Wang (2013). Role of aryl hydrocarbon receptor in cancer. Biochim Biophys Acta 1836:197–210.
    • (2013) Biochim Biophys Acta , vol.1836 , pp. 197-210
    • Feng, S.1    Cao, Z.2    Wang, X.3
  • 12
    • 39749129073 scopus 로고    scopus 로고
    • Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450
    • M.Fer, Y.Dreano, D.Lucas. (2008). Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450. Arch Biochem Biophys 471:116–125.
    • (2008) Arch Biochem Biophys , vol.471 , pp. 116-125
    • Fer, M.1    Dreano, Y.2    Lucas, D.3
  • 13
    • 0033060635 scopus 로고    scopus 로고
    • Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers
    • R.J.Fontana, K.S.Lown, M.F.Paine. (1999). Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers. Gastroenterology 117:89–98.
    • (1999) Gastroenterology , vol.117 , pp. 89-98
    • Fontana, R.J.1    Lown, K.S.2    Paine, M.F.3
  • 14
    • 84555178236 scopus 로고    scopus 로고
    • Comparative metabolomic and genomic analyses of TCDD-elicited metabolic disruption in mouse and rat liver
    • A.L.Forgacs, M.N.Kent, M.K.Makley. (2012). Comparative metabolomic and genomic analyses of TCDD-elicited metabolic disruption in mouse and rat liver. Toxicol Sci 125:41–55.
    • (2012) Toxicol Sci , vol.125 , pp. 41-55
    • Forgacs, A.L.1    Kent, M.N.2    Makley, M.K.3
  • 16
    • 0028987872 scopus 로고
    • The aryl hydrocarbon receptor complex
    • O.Hankinson (1995). The aryl hydrocarbon receptor complex. Annu Rev Pharmacol Toxicol 35:307–340.
    • (1995) Annu Rev Pharmacol Toxicol , vol.35 , pp. 307-340
    • Hankinson, O.1
  • 17
    • 84886031918 scopus 로고    scopus 로고
    • The AHR/ARNT dimer and transcriptional coactivators
    • Pohjanvirta R., (ed), Hoboken (NJ): John Wiley & Sons, Inc
    • O.Hankinson (2012) The AHR/ARNT dimer and transcriptional coactivators. In R.Pohjanvirta, ed. The AH receptor in biology and toxicology. Hoboken (NJ):John Wiley & Sons, Inc. 93–100.
    • (2012) The AH receptor in biology and toxicology , pp. 93-100
    • Hankinson, O.1
  • 18
    • 33745656989 scopus 로고    scopus 로고
    • Regulating the regulator: Factors that control levels and activity of the aryl hydrocarbon receptor
    • P.A.Harper, D.S.Riddick, A.B.Okey (2006). Regulating the regulator:Factors that control levels and activity of the aryl hydrocarbon receptor. Biochem Pharmacol 72:267–279.
    • (2006) Biochem Pharmacol , vol.72 , pp. 267-279
    • Harper, P.A.1    Riddick, D.S.2    Okey, A.B.3
  • 19
    • 37249074054 scopus 로고    scopus 로고
    • Hepatic transcriptional networks induced by exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • K.R.Hayes, G.M.Zastrow, M.Nukaya. (2007). Hepatic transcriptional networks induced by exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chem Res Toxicol 20:1573–1581.
    • (2007) Chem Res Toxicol , vol.20 , pp. 1573-1581
    • Hayes, K.R.1    Zastrow, G.M.2    Nukaya, M.3
  • 20
    • 34547092185 scopus 로고    scopus 로고
    • Cytochrome p450 epoxygenase promotes human cancer metastasis
    • J.G.Jiang, Y.G.Ning, C.Chen. (2007). Cytochrome p450 epoxygenase promotes human cancer metastasis. Cancer Res 67:6665–6674.
    • (2007) Cancer Res , vol.67 , pp. 6665-6674
    • Jiang, J.G.1    Ning, Y.G.2    Chen, C.3
  • 21
    • 69049109776 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholase A(2)alpha gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma Hepa-1c1c7 cells
    • M.Kinehara, I.Fukuda, K.Yoshida, H.Ashida. (2009). Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholase A(2)alpha gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma Hepa-1c1c7 cells. J Biosci Bioeng 108:277–281.
    • (2009) J Biosci Bioeng , vol.108 , pp. 277-281
    • Kinehara, M.1    Fukuda, I.2    Yoshida, K.3    Ashida, H.4
  • 22
    • 33750964517 scopus 로고    scopus 로고
    • Biochemical properties and pathophysiological roles of cytosolic phospholipase A2s
    • Y.Kita, T.Ohto, N.Uozumi, T.Shimizu. (2006). Biochemical properties and pathophysiological roles of cytosolic phospholipase A2s. Biochimica Et Biophysica Acta 1761:1317–1322.
    • (2006) Biochimica Et Biophysica Acta , vol.1761 , pp. 1317-1322
    • Kita, Y.1    Ohto, T.2    Uozumi, N.3    Shimizu, T.4
  • 23
    • 77958483338 scopus 로고    scopus 로고
    • Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice
    • A.K.Kopec, L.D.Burgoon, D.Ibrahim-Aibo. (2010). Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice. Toxicol Sci 118:286–297.
    • (2010) Toxicol Sci , vol.118 , pp. 286-297
    • Kopec, A.K.1    Burgoon, L.D.2    Ibrahim-Aibo, D.3
  • 24
    • 80053130505 scopus 로고    scopus 로고
    • Non-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 mice
    • A.K.Kopec, M.L.D’Souza, B.D.Mets. (2011). Non-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 mice. Toxicol Appl Pharmacol 256:154–167.
    • (2011) Toxicol Appl Pharmacol , vol.256 , pp. 154-167
    • Kopec, A.K.1    D’Souza, M.L.2    Mets, B.D.3
  • 25
    • 79956091586 scopus 로고    scopus 로고
    • Metabolomic analysis of liver and skeletal muscle tissues in C57BL/6J and DBA/2J mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • S.Lin, Z.Yang, H.Liu, Z.Cai (2011). Metabolomic analysis of liver and skeletal muscle tissues in C57BL/6J and DBA/2J mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol Biosyst 7:1956–1965.
    • (2011) Mol Biosyst , vol.7 , pp. 1956-1965
    • Lin, S.1    Yang, Z.2    Liu, H.3    Cai, Z.4
  • 26
    • 84907382483 scopus 로고    scopus 로고
    • AhR sensing of bacterial pigments regulates antibacterial defence
    • P.Moura-Alves, K.Fae, E.Houthuys. (2014). AhR sensing of bacterial pigments regulates antibacterial defence. Nature 512:387–392.
    • (2014) Nature , vol.512 , pp. 387-392
    • Moura-Alves, P.1    Fae, K.2    Houthuys, E.3
  • 27
    • 77957374067 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids and soluble epoxide hydrolase: Potential therapeutic targets for inflammation and its induced carcinogenesis
    • S.Norwood, J.Liao, B.D.Hammock. (2010). Epoxyeicosatrienoic acids and soluble epoxide hydrolase:Potential therapeutic targets for inflammation and its induced carcinogenesis. Am J Transl Res 2:447–457.
    • (2010) Am J Transl Res , vol.2 , pp. 447-457
    • Norwood, S.1    Liao, J.2    Hammock, B.D.3
  • 28
    • 80054041992 scopus 로고    scopus 로고
    • An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
    • C.A.Opitz, U.M.Litzenburger, F.Sahm. (2011). An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478:197–203.
    • (2011) Nature , vol.478 , pp. 197-203
    • Opitz, C.A.1    Litzenburger, U.M.2    Sahm, F.3
  • 29
    • 84855453198 scopus 로고    scopus 로고
    • Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice
    • D.Panigrahy, M.L.Edin, C.R.Lee. (2012). Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest 122:178–191.
    • (2012) J Clin Invest , vol.122 , pp. 178-191
    • Panigrahy, D.1    Edin, M.L.2    Lee, C.R.3
  • 30
    • 34547138678 scopus 로고    scopus 로고
    • Peroxisomal proliferator-activated receptor-alpha-dependent inhibition of endothelial cell proliferation and tumorigenesis
    • A.Pozzi, M.R.Ibanez, A.E.Gatica. (2007). Peroxisomal proliferator-activated receptor-alpha-dependent inhibition of endothelial cell proliferation and tumorigenesis. J Biol Chem 282:17685–17695.
    • (2007) J Biol Chem , vol.282 , pp. 17685-17695
    • Pozzi, A.1    Ibanez, M.R.2    Gatica, A.E.3
  • 31
    • 77951247264 scopus 로고    scopus 로고
    • The anti-tumorigenic properties of peroxisomal proliferator-activated receptor alpha are arachidonic acid epoxygenase-mediated
    • A.Pozzi, V.Popescu, S.Yang. (2010). The anti-tumorigenic properties of peroxisomal proliferator-activated receptor alpha are arachidonic acid epoxygenase-mediated. J Biol Chem 285:12840–12850.
    • (2010) J Biol Chem , vol.285 , pp. 12840-12850
    • Pozzi, A.1    Popescu, V.2    Yang, S.3
  • 32
    • 33646674486 scopus 로고    scopus 로고
    • CYP1A in TCDD toxicity and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates
    • A.B.Rifkind (2006). CYP1A in TCDD toxicity and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates. Drug Metab Rev 38:291–335.
    • (2006) Drug Metab Rev , vol.38 , pp. 291-335
    • Rifkind, A.B.1
  • 33
    • 0032524377 scopus 로고    scopus 로고
    • Arachidonic acid metabolism in the marine fish Stenotomus chrysops (Scup) and the effects of cytochrome P450 1A inducers
    • J.J.Schlezinger, C.Parker, D.C.Zeldin, J.J.Stegeman. (1998). Arachidonic acid metabolism in the marine fish Stenotomus chrysops (Scup) and the effects of cytochrome P450 1A inducers. Arch Biochem Biophys 353:265–275.
    • (1998) Arch Biochem Biophys , vol.353 , pp. 265-275
    • Schlezinger, J.J.1    Parker, C.2    Zeldin, D.C.3    Stegeman, J.J.4
  • 34
    • 1642372110 scopus 로고    scopus 로고
    • Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: Highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid
    • D.Schwarz, P.Kisselev, S.S.Ericksen. (2004). Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1:Highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid. Biochem Pharmacol 67:1445–1457.
    • (2004) Biochem Pharmacol , vol.67 , pp. 1445-1457
    • Schwarz, D.1    Kisselev, P.2    Ericksen, S.S.3
  • 35
    • 84922507875 scopus 로고    scopus 로고
    • 540 epoxygenase pathway of polyunsaturated fatty acid metabolism
    • 540 epoxygenase pathway of polyunsaturated fatty acid metabolism. Biochimica Biophysica Acta 1851:356–365.
    • (2015) Biochimica Biophysica Acta , vol.1851 , pp. 356-365
    • Spector, A.A.1    Kim, H.Y.2
  • 36
    • 79955629014 scopus 로고    scopus 로고
    • The function of cytochrome P450 1A1 enzyme (CYP1A1) and aryl hydrocarbon receptor (AhR) in the placenta
    • L.Stejskalova, P.Pavek (2011). The function of cytochrome P450 1A1 enzyme (CYP1A1) and aryl hydrocarbon receptor (AhR) in the placenta. Curr Pharm Biotechnol 12:715–730.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 715-730
    • Stejskalova, L.1    Pavek, P.2
  • 37
    • 0032520752 scopus 로고    scopus 로고
    • Modulation of prostaglandin H Synthase-2 mRNA expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice
    • C.Vogel, U.S.Schuhmacher. G.H.Degen. (1998). Modulation of prostaglandin H Synthase-2 mRNA expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice. Arch Biochem Biophys 352:265–271.
    • (1998) Arch Biochem Biophys , vol.352 , pp. 265-271
    • Vogel, C.1    Schuhmacher, U.S.2    Degen, G.H.3
  • 38
    • 84887445958 scopus 로고    scopus 로고
    • Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung
    • J.Yang, P.Solaimani, H.Dong. (2013). Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung. J Toxicol Sci 38:833–836.
    • (2013) J Toxicol Sci , vol.38 , pp. 833-836
    • Yang, J.1    Solaimani, P.2    Dong, H.3
  • 39
    • 84876218926 scopus 로고    scopus 로고
    • Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis
    • G.Zhang, D.Panigraphy, L.M.Mahakian. (2013). Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci USA 110:6530–6535.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 6530-6535
    • Zhang, G.1    Panigraphy, D.2    Mahakian, L.M.3
  • 40
    • 84904990664 scopus 로고    scopus 로고
    • Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis
    • G.Zhang, D.Panigraphy, S.H.Hwang. (2014). Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. Proc Natl Acad Sci USA 111:11127–11132. PMCID:PMC4121808.
    • (2014) . Proc Natl Acad Sci USA , vol.111 , pp. 11127-11132
    • Zhang, G.1    Panigraphy, D.2    Hwang, S.H.3


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