Salvianolic acid B ameliorates depressive-like behaviors in chronic mild stress-treated mice: Involvement of the neuroinflammatory pathway

Acta Pharmacologica Sinica

Volumn 37, Issue 9, 2016, Pages 1141-1153

  Zhang, Jin Qiang ^a   Wu, Xiao Hui ^a   Feng, Yi ^a   Xie, Xiao Fang ^b   Fan, Yong Hua ^a   Yan, Shuo ^a   Zhao, Qiu Ying ^a   Peng, Cheng ^b   You, Zi Li ^a  

^a UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

antidepressant; apoptosis; chronic mild stress; cytokines; imipramine; major depressive disorder; microglia activation; salvianolic acid B

Indexed keywords

CASPASE 3; CORTICOSTERONE; IMIPRAMINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; SALVIANOLIC ACID B; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; BENZOFURAN DERIVATIVE; CYTOKINE; HERBACEOUS AGENT;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN TISSUE; CELL ACTIVATION; CHRONIC MILD STRESS; CHRONIC STRESS; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; DRUG MECHANISM; ELISA KIT; FORCED SWIM TEST; GENE EXPRESSION; HIPPOCAMPUS; IMMUNOFLUORESCENCE; MALE; MICROGLIA; MOUSE; MOUSE MODEL; NONHUMAN; PROTEIN BLOOD LEVEL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; ANIMAL; BLOOD; C57BL MOUSE; DEPRESSIVE DISORDER, MAJOR; DRUG EFFECTS; DRUG THERAPY; GENETICS; IMMUNOLOGY; IMMUNOMODULATION; MENTAL STRESS; NERVE CELL; PATHOLOGY; PSYCHOLOGY;

ANIMALS; APOPTOSIS; BEHAVIOR, ANIMAL; BENZOFURANS; CEREBRAL CORTEX; CORTICOSTERONE; CYTOKINES; DEPRESSIVE DISORDER, MAJOR; DRUGS, CHINESE HERBAL; GENE EXPRESSION; HIPPOCAMPUS; MALE; MICE, INBRED C57BL; MICROGLIA; NEUROIMMUNOMODULATION; NEURONS; STRESS, PSYCHOLOGICAL;

EID: 84984918880     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2016.63     Document Type: Article

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