Prolonged Restraint Stress Increases IL-6, Reduces IL-10, and Causes Persistent Depressive-Like Behavior That Is Reversed by Recombinant IL-10

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Voorhees, Jeffrey L ^a,b   Tarr, Andrew J ^b   Wohleb, Eric S ^b   Godbout, Jonathan P ^b   Mo, Xiaokui ^b   Sheridan, John F ^b   Eubank, Timothy D ^a,b   Marsh, Clay B ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; GAMMA INTERFERON; GLUCOCORTICOID; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR CHANGE; BRAIN CORTEX; BRAIN REGION; CAUSAL ATTRIBUTION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; FEMALE; HIPPOCAMPUS; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPLEEN WEIGHT; STRESS; WEIGHT REDUCTION;

ANIMALS; BEHAVIOR, ANIMAL; DEPRESSION; IMMOBILIZATION; INTERLEUKIN-10; INTERLEUKIN-6; MICE; RECOMBINANT PROTEINS; STRESS, PHYSIOLOGICAL; TIME FACTORS;

EID: 84874777901     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058488     Document Type: Article

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