CRISPR-Cas9 enables conditional mutagenesis of challenging loci

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Schick, Joel A ^a   Seisenberger, Claudia ^a   Beig, Joachim ^a   Bürger, Antje ^a   Iyer, Vivek ^b   Maier, Viola ^a   Perera, Sajith ^b   Rosen, Barry ^b,c   Skarnes, William C ^b   Wurst, Wolfgang ^a,d,e,f  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^f UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANIMAL MODEL; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; HUMAN EXPERIMENT; KNOCKOUT MOUSE; MOUSE; MUTAGENESIS; NONHUMAN; ANIMAL; C57BL MOUSE; CRISPR CAS SYSTEM; GENE LOCUS; GENE TARGETING; GENETICS;

ANIMALS; CRISPR-CAS SYSTEMS; GENE TARGETING; GENETIC LOCI; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENESIS;

EID: 84984868418     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep32326     Document Type: Article

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