Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety

Neuropsychopharmacology

Volumn 41, Issue 13, 2016, Pages 3103-3113

  Shen, Erica Y ^a   Jiang, Yan ^a   Javidfar, Behnam ^a   Kassim, Bibi ^a   Loh, Yong Hwee E ^a   Ma, Qi ^b   Mitchell, Amanda C ^a   Pothula, Venu ^a   Stewart, A Francis ^c   Ernst, Patricia ^d   Yao, Wei Dong ^e   Martin, Gilles ^b   Shen, Li ^a   Jakovcevski, Mira ^f   Akbarian, Schahram ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^d University of Colorado Denver and Children s Hospital Colorado   (United States)

^e State University of New York Upstate Medical University: College of Medicine   (United States)

^f MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; HISTONE METHYLTRANSFERASE; LYSINE METHYLTRANSFERASE 2A; TRANSCRIPTOME; UNCLASSIFIED DRUG; HISTONE LYSINE METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA PROTEIN; MLL PROTEIN, MOUSE; NERVE PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; CELL LOSS; CONTROLLED STUDY; DEPRESSION; FEMALE; FLOW CYTOMETRY; FOREBRAIN; GENE EXPRESSION; HISTONE MODIFICATION; LOCOMOTION; LONG TERM POTENTIATION; MALE; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; NUCLEUS ACCUMBENS; ORTHOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; VENTRAL STRIATUM; ACTION POTENTIAL; ANIMAL; C57BL MOUSE; CIRCADIAN RHYTHM; CYTOLOGY; DEFICIENCY; DISEASE MODEL; DNA MICROARRAY; DRUG EFFECTS; DRUG THERAPY; GENETICS; KNOCKOUT MOUSE; METABOLISM; NEWBORN; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ANXIETY; CIRCADIAN RHYTHM; DISEASE MODELS, ANIMAL; DOPAMINE AGENTS; FEMALE; HISTONE-LYSINE N-METHYLTRANSFERASE; LOCOMOTION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; VENTRAL STRIATUM;

EID: 84984838248     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2016.144     Document Type: Article

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