-
1
-
-
84871511126
-
Deaths: Preliminary data for 2011
-
Hoyert DL, Xu J. Deaths: preliminary data for 2011. Natl Vital Stat Rep 2012;61(6):1-65.
-
(2012)
Natl Vital Stat Rep
, vol.61
, Issue.6
, pp. 1-65
-
-
Hoyert, D.L.1
Xu, J.2
-
2
-
-
33847172367
-
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
-
TORCH investigators
-
Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, Jones PW, Yates JC, Vestbo J; TORCH investigators. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 2007;356:775-789.
-
(2007)
N Engl J Med
, vol.356
, pp. 775-789
-
-
Calverley, P.M.1
Anderson, J.A.2
Celli, B.3
Ferguson, G.T.4
Jenkins, C.5
Jones, P.W.6
Yates, J.C.7
Vestbo, J.8
-
3
-
-
0036598241
-
New treatments for COPD
-
Barnes PJ. New treatments for COPD. Nat Rev Drug Discov 2002;1: 437-446.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 437-446
-
-
Barnes, P.J.1
-
4
-
-
84879693217
-
New anti-inflammatory targets for chronic obstructive pulmonary disease
-
Barnes PJ. New anti-inflammatory targets for chronic obstructive pulmonary disease. Nat Rev Drug Discov 2013;12:543-559.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 543-559
-
-
Barnes, P.J.1
-
5
-
-
0030990977
-
Gender difference in smoking effects on lung function and risk of hospitalization for COPD: Results from a Danish longitudinal population study
-
Prescott E, Bjerg AM, Andersen PK, Lange P, Vestbo J. Gender difference in smoking effects on lung function and risk of hospitalization for COPD: results from a Danish longitudinal population study. Eur Respir J 1997;10:822-827.
-
(1997)
Eur Respir J
, vol.10
, pp. 822-827
-
-
Prescott, E.1
Bjerg, A.M.2
Andersen, P.K.3
Lange, P.4
Vestbo, J.5
-
6
-
-
25444509773
-
Accelerated decline in lung function in smoking women with airway obstruction: SAPALDIA 2 cohort study
-
SAPALDIA team
-
Downs SH, Brändli O, Zellweger JP, Schindler C, Künzli N, Gerbase MW, Burdet L, Bettschart R, Zemp E, Frey M, et al.; SAPALDIA team. Accelerated decline in lung function in smoking women with airway obstruction: SAPALDIA 2 cohort study. Respir Res 2005;6:45.
-
(2005)
Respir Res
, vol.6
, pp. 45
-
-
Downs, S.H.1
Brändli, O.2
Zellweger, J.P.3
Schindler, C.4
Künzli, N.5
Gerbase, M.W.6
Burdet, L.7
Bettschart, R.8
Zemp, E.9
Frey, M.10
-
7
-
-
0037008318
-
Chronic obstructive pulmonary disease surveillance-United States, 1971-2000
-
Mannino DM, Homa DM, Akinbami LJ, Ford ES, Redd SC. Chronic obstructive pulmonary disease surveillance-United States, 1971-2000. MMWR Surveill Summ 2002;51(SS06): 1-16.
-
(2002)
MMWR Surveill Summ
, vol.51
, Issue.SS06
, pp. 1-16
-
-
Mannino, D.M.1
Homa, D.M.2
Akinbami, L.J.3
Ford, E.S.4
Redd, S.C.5
-
8
-
-
27844598334
-
-
Centers for Disease Control and Prevention. Health data interactive [accessed Mar 5]
-
Centers for Disease Control and Prevention. National Center for Health Statistics. Health data interactive [accessed 2016 Mar 5]. Available from: www.cdc.gov/nchs/hdi.htm
-
(2016)
National Center for Health Statistics
-
-
-
9
-
-
34547588847
-
Sex differences in severe pulmonary emphysema
-
National Emphysema Treatment Trial Research Group
-
Martinez FJ, Curtis JL, Sciurba F, Mumford J, Giardino ND, Weinmann G, Kazerooni E, Murray S, Criner GJ, Sin DD, et al.; National Emphysema Treatment Trial Research Group. Sex differences in severe pulmonary emphysema. Am J Respir Crit Care Med 2007; 176:243-252.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 243-252
-
-
Martinez, F.J.1
Curtis, J.L.2
Sciurba, F.3
Mumford, J.4
Giardino, N.D.5
Weinmann, G.6
Kazerooni, E.7
Murray, S.8
Criner, G.J.9
Sin, D.D.10
-
10
-
-
0242468653
-
Lung cancer screening: A different paradigm
-
McWilliams A, Mayo J, MacDonald S, leRiche JC, Palcic B, Szabo E, Lam S. Lung cancer screening: a different paradigm. Am J Respir Crit Care Med 2003;168:1167-1173.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 1167-1173
-
-
McWilliams, A.1
Mayo, J.2
MacDonald, S.3
LeRiche, J.C.4
Palcic, B.5
Szabo, E.6
Lam, S.7
-
11
-
-
44449107593
-
Airway wall thickness assessed using computed tomography and optical coherence tomography
-
Coxson HO, Quiney B, Sin DD, Xing L, McWilliams AM, Mayo JR, Lam S. Airway wall thickness assessed using computed tomography and optical coherence tomography. Am J Respir Crit Care Med 2008; 177:1201-1206.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 1201-1206
-
-
Coxson, H.O.1
Quiney, B.2
Sin, D.D.3
Xing, L.4
McWilliams, A.M.5
Mayo, J.R.6
Lam, S.7
-
12
-
-
69949114515
-
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
-
Hecker L, Vittal R, Jones T, Jagirdar R, Luckhardt TR, Horowitz JC, Pennathur S, Martinez FJ, Thannickal VJ. NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nat Med 2009;15:1077-1081.
-
(2009)
Nat Med
, vol.15
, pp. 1077-1081
-
-
Hecker, L.1
Vittal, R.2
Jones, T.3
Jagirdar, R.4
Luckhardt, T.R.5
Horowitz, J.C.6
Pennathur, S.7
Martinez, F.J.8
Thannickal, V.J.9
-
13
-
-
34547815598
-
Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in Guinea pigs
-
Churg A, Wang R, Wang X, Onnervik PO, Thim K, Wright JL. Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs. Thorax 2007; 62:706-713.
-
(2007)
Thorax
, vol.62
, pp. 706-713
-
-
Churg, A.1
Wang, R.2
Wang, X.3
Onnervik, P.O.4
Thim, K.5
Wright, J.L.6
-
14
-
-
77956036249
-
NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts
-
Amara N, Goven D, Prost F, Muloway R, Crestani B, Boczkowski J. NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts. Thorax 2010;65:733-738.
-
(2010)
Thorax
, vol.65
, pp. 733-738
-
-
Amara, N.1
Goven, D.2
Prost, F.3
Muloway, R.4
Crestani, B.5
Boczkowski, J.6
-
15
-
-
84896729661
-
Calcineurin Ab regulates NADPH oxidase (Nox) expression and activity via nuclear factor of activated T cells (NFAT) in response to high glucose
-
Williams CR, Gooch JL. Calcineurin Ab regulates NADPH oxidase (Nox) expression and activity via nuclear factor of activated T cells (NFAT) in response to high glucose. J Biol Chem 2014;289: 4896-4905.
-
(2014)
J Biol Chem
, vol.289
, pp. 4896-4905
-
-
Williams, C.R.1
Gooch, J.L.2
-
16
-
-
37349004761
-
Understanding the biological differences in susceptibility to chronic obstructive pulmonary disease between men and women
-
Sin DD, Cohen SB, Day A, Coxson H, ParéPD. Understanding the biological differences in susceptibility to chronic obstructive pulmonary disease between men and women. Proc Am Thorac Soc 2007;4:671-674.
-
(2007)
Proc Am Thorac Soc
, vol.4
, pp. 671-674
-
-
Sin, D.D.1
Cohen, S.B.2
Day, A.3
Coxson, H.4
Paré, P.D.5
-
17
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 2004;114: 1248-1259.
-
(2004)
J Clin Invest
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
Yamamoto, M.7
Petrache, I.8
Tuder, R.M.9
Biswal, S.10
-
18
-
-
0025142668
-
DT-diaphorase: Purification, properties, and function
-
Lind C, Cadenas E, Hochstein P, Ernster L. DT-diaphorase: purification, properties, and function. Methods Enzymol 1990;186:287-301.
-
(1990)
Methods Enzymol
, vol.186
, pp. 287-301
-
-
Lind, C.1
Cadenas, E.2
Hochstein, P.3
Ernster, L.4
-
19
-
-
84892364503
-
Lung remodeling mechanisms in chronic lung diseases
-
Zhong J, Roth M. Lung remodeling mechanisms in chronic lung diseases. Curr Opin Allergy Clin Immunol 2014;14:69-76.
-
(2014)
Curr Opin Allergy Clin Immunol
, vol.14
, pp. 69-76
-
-
Zhong, J.1
Roth, M.2
-
20
-
-
0242721223
-
Cigarette smoke produces airway wall remodeling in rat tracheal explants
-
Wang RD, Tai H, Xie C, Wang X, Wright JL, Churg A. Cigarette smoke produces airway wall remodeling in rat tracheal explants. Am J Respir Crit Care Med 2003;168:1232-1236.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 1232-1236
-
-
Wang, R.D.1
Tai, H.2
Xie, C.3
Wang, X.4
Wright, J.L.5
Churg, A.6
-
21
-
-
26244452596
-
Transforming growth factor-beta1 drives airway remodeling in cigarette smoke-exposed tracheal explants
-
Wang RD, Wright JL, Churg A. Transforming growth factor-beta1 drives airway remodeling in cigarette smoke-exposed tracheal explants. Am J Respir Cell Mol Biol 2005;33:387-393.
-
(2005)
Am J Respir Cell Mol Biol
, vol.33
, pp. 387-393
-
-
Wang, R.D.1
Wright, J.L.2
Churg, A.3
-
22
-
-
34547850670
-
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation
-
Serrander L, Cartier L, Bedard K, Banfi B, Lardy B, Plastre O, Sienkiewicz A, FórróL, Schlegel W, Krause KH. NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation. Biochem J 2007;406:105-114.
-
(2007)
Biochem J
, vol.406
, pp. 105-114
-
-
Serrander, L.1
Cartier, L.2
Bedard, K.3
Banfi, B.4
Lardy, B.5
Plastre, O.6
Sienkiewicz, A.7
Fórró, L.8
Schlegel, W.9
Krause, K.H.10
-
23
-
-
84872491620
-
Nox4 modulates collagen production stimulated by transforming growth factor b1 in vivo and in vitro
-
Chan EC, Peshavariya HM, Liu GS, Jiang F, Lim SY, Dusting GJ. Nox4 modulates collagen production stimulated by transforming growth factor b1 in vivo and in vitro. Biochem Biophys Res Commun 2013; 430:918-925.
-
(2013)
Biochem Biophys Res Commun
, vol.430
, pp. 918-925
-
-
Chan, E.C.1
Peshavariya, H.M.2
Liu, G.S.3
Jiang, F.4
Lim, S.Y.5
Dusting, G.J.6
-
24
-
-
33646593852
-
Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells
-
Sturrock A, Cahill B, Norman K, Huecksteadt TP, Hill K, Sanders K, Karwande SV, Stringham JC, Bull DA, Gleich M, et al. Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2006;290: L661-L673.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
, pp. L661-L673
-
-
Sturrock, A.1
Cahill, B.2
Norman, K.3
Huecksteadt, T.P.4
Hill, K.5
Sanders, K.6
Karwande, S.V.7
Stringham, J.C.8
Bull, D.A.9
Gleich, M.10
-
25
-
-
0020073475
-
Normal values of total respiratory resistance and reactance determined by forced oscillations: Influence of smoking
-
Làndsér FJ, Clément J, Van de Woestijne KP. Normal values of total respiratory resistance and reactance determined by forced oscillations: influence of smoking. Chest 1982;81:586-591.
-
(1982)
Chest
, vol.81
, pp. 586-591
-
-
Làndsér, F.J.1
Clément, J.2
Van De Woestijne, K.P.3
-
26
-
-
0035040557
-
Effects of gestation and antenatal steroid on airway and tissue mechanics in newborn lambs
-
Pillow JJ, Hall GL, Willet KE, Jobe AH, Hantos Z, Sly PD. Effects of gestation and antenatal steroid on airway and tissue mechanics in newborn lambs. Am J Respir Crit Care Med 2001; 163:1158-1163.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1158-1163
-
-
Pillow, J.J.1
Hall, G.L.2
Willet, K.E.3
Jobe, A.H.4
Hantos, Z.5
Sly, P.D.6
-
27
-
-
72749106065
-
Evidence for dysanapsis using computed tomographic imaging of the airways in older ex-smokers
-
Sheel AW, Guenette JA, Yuan R, Holy L, Mayo JR, McWilliams AM, Lam S, Coxson HO. Evidence for dysanapsis using computed tomographic imaging of the airways in older ex-smokers. J Appl Physiol (1985) 2009;107:1622-1628.
-
(2009)
J Appl Physiol (1985)
, vol.107
, pp. 1622-1628
-
-
Sheel, A.W.1
Guenette, J.A.2
Yuan, R.3
Holy, L.4
Mayo, J.R.5
McWilliams, A.M.6
Lam, S.7
Coxson, H.O.8
-
28
-
-
0023607704
-
Airway size is related to sex but not lung size in normal adults
-
Martin TR, Castile RG, Fredberg JJ, Wohl ME, Mead J. Airway size is related to sex but not lung size in normal adults. J Appl Physiol (1985) 1987;63:2042-2047.
-
(1987)
J Appl Physiol (1985)
, vol.63
, pp. 2042-2047
-
-
Martin, T.R.1
Castile, R.G.2
Fredberg, J.J.3
Wohl, M.E.4
Mead, J.5
-
30
-
-
57449104934
-
17beta-Estradiol inhibits Ca21-dependent homeostasis of airway surface liquid volume in human cystic fibrosis airway epithelia
-
Coakley RD, Sun H, Clunes LA, Rasmussen JE, Stackhouse JR, Okada SF, Fricks I, Young SL, Tarran R. 17beta-Estradiol inhibits Ca21-dependent homeostasis of airway surface liquid volume in human cystic fibrosis airway epithelia. J Clin Invest 2008;118:4025-4035.
-
(2008)
J Clin Invest
, vol.118
, pp. 4025-4035
-
-
Coakley, R.D.1
Sun, H.2
Clunes, L.A.3
Rasmussen, J.E.4
Stackhouse, J.R.5
Okada, S.F.6
Fricks, I.7
Young, S.L.8
Tarran, R.9
-
31
-
-
57449098489
-
Cystic fibrosis and estrogens: A perfect storm
-
Zeitlin PL. Cystic fibrosis and estrogens: a perfect storm. J Clin Invest 2008;118:3841-3844.
-
(2008)
J Clin Invest
, vol.118
, pp. 3841-3844
-
-
Zeitlin, P.L.1
-
32
-
-
84877906606
-
Calreticulin regulates transforming growth factor-b-stimulated extracellular matrix production
-
Zimmerman KA, Graham LV, Pallero MA, Murphy-Ullrich JE. Calreticulin regulates transforming growth factor-b-stimulated extracellular matrix production. J Biol Chem 2013;288: 14584-14598.
-
(2013)
J Biol Chem
, vol.288
, pp. 14584-14598
-
-
Zimmerman, K.A.1
Graham, L.V.2
Pallero, M.A.3
Murphy-Ullrich, J.E.4
-
33
-
-
2442520434
-
Involvement of calcineurin in transforming growth factor-beta-mediated regulation of extracellular matrix accumulation
-
Gooch JL, Gorin Y, Zhang BX, Abboud HE. Involvement of calcineurin in transforming growth factor-beta-mediated regulation of extracellular matrix accumulation. J Biol Chem 2004;279: 15561-15570.
-
(2004)
J Biol Chem
, vol.279
, pp. 15561-15570
-
-
Gooch, J.L.1
Gorin, Y.2
Zhang, B.X.3
Abboud, H.E.4
-
34
-
-
79551557991
-
TGF-b regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells
-
Michaeloudes C, Sukkar MB, Khorasani NM, Bhavsar PK, Chung KF. TGF-b regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2011;300:L295-L304.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
, pp. L295-L304
-
-
Michaeloudes, C.1
Sukkar, M.B.2
Khorasani, N.M.3
Bhavsar, P.K.4
Chung, K.F.5
-
35
-
-
84903542975
-
Estradiol increases mucus synthesis in bronchial epithelial cells
-
Tam A, Wadsworth S, Dorscheid D, Man SF, Sin DD. Estradiol increases mucus synthesis in bronchial epithelial cells. PLoS One 2014;9:e100633.
-
(2014)
PLoS One
, vol.9
, pp. e100633
-
-
Tam, A.1
Wadsworth, S.2
Dorscheid, D.3
Man, S.F.4
Sin, D.D.5
-
36
-
-
20644466433
-
NFAT proteins: Key regulators of T-cell development and function
-
Macian F. NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol 2005;5:472-484.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 472-484
-
-
Macian, F.1
-
37
-
-
15444379857
-
Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia
-
Lavigne MC, Eppihimer MJ. Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia. Biochem Biophys Res Commun 2005;330:194-203.
-
(2005)
Biochem Biophys Res Commun
, vol.330
, pp. 194-203
-
-
Lavigne, M.C.1
Eppihimer, M.J.2
-
38
-
-
68849132219
-
Effects of the menstrual cycle on lung function variables in women with asthma
-
Farha S, Asosingh K, Laskowski D, Hammel J, Dweik RA, Wiedemann HP, Erzurum SC. Effects of the menstrual cycle on lung function variables in women with asthma. Am J Respir Crit Care Med 2009; 180:304-310.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 304-310
-
-
Farha, S.1
Asosingh, K.2
Laskowski, D.3
Hammel, J.4
Dweik, R.A.5
Wiedemann, H.P.6
Erzurum, S.C.7
-
39
-
-
84876064424
-
Bronchiolitis in young female smokers
-
Sayiner A, Hague C, Ajlan A, Leipsic J, Wierenga L, Krowchuk NM, Ceylan N, Sayiner A, Sin DD, Coxson HO. Bronchiolitis in young female smokers. Respir Med 2013;107:732-738.
-
(2013)
Respir Med
, vol.107
, pp. 732-738
-
-
Sayiner, A.1
Hague, C.2
Ajlan, A.3
Leipsic, J.4
Wierenga, L.5
Krowchuk, N.M.6
Ceylan, N.7
Sayiner, A.8
Sin, D.D.9
Coxson, H.O.10
-
40
-
-
0016389488
-
Pathologic changes in the peripheral airways of young cigarette smokers
-
Niewoehner DE, Kleinerman J, Rice DB. Pathologic changes in the peripheral airways of young cigarette smokers. N Engl J Med 1974; 291:755-758.
-
(1974)
N Engl J Med
, vol.291
, pp. 755-758
-
-
Niewoehner, D.E.1
Kleinerman, J.2
Rice, D.B.3
|