The role of hippocampal insulin signaling on postoperative cognitive dysfunction in an aged rat model of abdominal surgery

Life Sciences

Volumn 162, Issue , 2016, Pages 87-94

  Kawano, Takashi ^a   Iwata, Hideki ^a   Aoyama, Bun ^a   Nishigaki, Atsushi ^a   Yamanaka, Daiki ^a   Tateiwa, Hiroki ^a   Eguchi, Satoru ^b   Locatelli, Fabricio M ^a   Yokoyama, Masataka ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Insulin; Microglia; Neuroinflammation; Postoperative cognitive disorders

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR; GLYCOGEN SYNTHASE KINASE 3;

ABDOMINAL SURGERY; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EX VIVO STUDY; HIPPOCAMPUS; MALE; MEMORY DISORDER; MICROGLIA; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; POSTOPERATIVE COGNITIVE DYSFUNCTION; RAT; SIGNAL TRANSDUCTION; ANIMAL; COGNITIVE DEFECT; ENZYMOLOGY; METABOLISM; POSTOPERATIVE PERIOD; WISTAR RAT;

ANIMALS; COGNITION DISORDERS; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; INSULIN; MALE; POSTOPERATIVE PERIOD; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 84984706987     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2016.08.020     Document Type: Article

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