Pregabalin can prevent, but not treat, cognitive dysfunction following abdominal surgery in aged rats

Life Sciences

Volumn 148, Issue , 2016, Pages 211-219

  Kawano, Takashi ^a   Eguchi, Satoru ^b   Iwata, Hideki ^a   Yamanaka, Daiki ^a   Tateiwa, Hiroki ^a   Locatelli, Fabricio M ^a   Yokoyama, Masataka ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Microglia; Neuroinflammation; Post operative cognitive dysfunction

Indexed keywords

INTERLEUKIN 1BETA; PREGABALIN; TUMOR NECROSIS FACTOR ALPHA;

ABDOMINAL SURGERY; AGED; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITION; COGNITIVE FUNCTION TEST; CONTROLLED STUDY; CROSS CIRCULATION; CYTOKINE RELEASE; MALE; MICROGLIA; NERVOUS SYSTEM INFLAMMATION; NEUROTRANSMISSION; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; PARABIOSIS; POSTOPERATIVE COGNITIVE DYSFUNCTION; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; RAT; THERAPY EFFECT; ABDOMINAL WALL MUSCULATURE; AGING; ANIMAL; COGNITION DISORDERS; DRUG EFFECTS; POSTOPERATIVE COMPLICATIONS; PREOPERATIVE CARE; PROCEDURES; PSYCHOLOGY; SURGERY; TREATMENT OUTCOME; WISTAR RAT;

ABDOMINAL MUSCLES; AGING; ANIMALS; COGNITION DISORDERS; MALE; POSTOPERATIVE COMPLICATIONS; PREGABALIN; PREOPERATIVE CARE; RATS; RATS, WISTAR; TREATMENT OUTCOME;

EID: 84958986233     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2016.02.021     Document Type: Article

References (35)

1. J.T. Moller, P. Cluitmans, L.S. Rasmussen, P. Houx, H. Rasmussen, J. Canet, P. Rabbitt, J. Jolles, K. Larsen, C.D. Hanning, O. Langeron, T. Johnson, P.M. Lauven, P.A. Kristensen, A. Biedler, H. van Beem, O. Fraidakis, J.H. Silverstein, J.E. Beneken, and J.S. Gravenstein Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction Lancet 351 1998 857 861
2. S. Deiner, and J.H. Silverstein Postoperative delirium and cognitive dysfunction Br. J. Anaesth. 103 2009 i41 i46
3. J. Steinmetz, K.B. Christensen, T. Lund, N. Lohse, and L.S. Rasmussen ISPOCD group, long-term consequences of postoperative cognitive dysfunction Anesthesiology 110 2009 548 555
4. X.Z. Cao, H. Ma, J.K. Wang, F. Liu, B.Y. Wu, A.Y. Tian, L.L. Wang, and W.F. Tan Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats Prog. Neuro-Psychopharmacol. Biol. Psychiatry 34 2010 1426 1432
5. I.B. Hovens, R.G. Schoemaker, E.A. van der Zee, A.R. Absalom, E. Heineman, and B.L. van Leeuwen Postoperative cognitive dysfunction: involvement of neuroinflammation and neuronal functioning Brain Behav. Immun. 38 2014 202 210
6. I.B. Hovens, B.L. van Leeuwen, C. Nyakas, E. Heineman, E.A. van der Zee, and R.G. Schoemaker Postoperative cognitive dysfunction and microglial activation in associated brain regions in old rats Neurobiol. Learn. Mem. 118 2015 74 79
7. R.M. Bluthé, M. Pawlowski, S. Suarez, P. Parnet, Q. Pittman, K.W. Kelley, and R. Dantzer Synergy between tumor necrosis factor alpha and interleukin-1 in the induction of sickness behavior in mice Psychoneuroendocrinology 19 1994 197 207
8. N. Terrando, C. Monaco, D. Ma, B.M. Foxwell, M. Feldmann, and M. Maze Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline Proc. Natl. Acad. Sci. U. S. A. 107 2011 20518 20522
9. C.J. Wilson, C.E. Finch, and H.J. Cohen Cytokines and cognition - the case for a head-to-toe inflammatory paradigm J. Am. Geriatr. Soc. 50 2002 2041 2056
10. R.N. Dilger, and R.W. Johnson Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system J. Leukoc. Biol. 84 2008 932 939
11. T. Kawano, S. Eguchi, H. Iwata, T. Tamura, N. Kumagai, and M. Yokoyama Impact of preoperative environmental enrichment on prevention of development of cognitive impairment following abdominal surgery in a rat model Anesthesiology 123 2015 160 170
12. B.F. Shneker, and J.W. McAuley Pregabalin: a new neuromodulator with broad therapeutic indications Ann. Pharmacother. 39 2005 2029 2037
13. N.M. Gajraj Pregabalin: its pharmacology and use in pain management Anesth. Analg. 105 2007 1805 1815
14. R.L. Cole, S.M. Lechner, M.E. Williams, P. Prodanovich, L. Bleicher, M.A. Varney, and G. Gu Differential distribution of voltage-gated calcium channel alpha-2 delta (α2δ) subunit mRNA-containing cells in the rat central nervous system and the dorsal root ganglia J. Comp. Neurol. 491 2005 246 269
15. N. Klugbauer, L. Lacinová, E. Marais, M. Hobom, and F. Hofmann Molecular diversity of the calcium channel α2δ subunit J. Neurosci. 19 1999 684 691
16. M.M. Valente, V. Bortolotto, B. Cuccurazzu, F. Ubezio, V. Meneghini, M.T. Francese, P.L. Canonico, and M. Grilli α2δ ligands act as positive modulators of adult hippocampal neurogenesis and prevent depression-like behavior induced by chronic restraint stress Mol. Pharmacol. 82 2012 271 280
17. K.D. Micheva, C.P. Taylor, and S.J. Smith Pregabalin reduces the release of synaptic vesicles from cultured hippocampal neurons Mol. Pharmacol. 70 2006 467 476
18. C.J. Siok, C.P. Taylor, and M. Hajós Anxiolytic profile of pregabalin on elicited hippocampal theta oscillation Neuropharmacology 56 2009 379 385
19. W. Lau, C. Dykstra, S. Thevarkunnel, L.B. Silenieks, I.A. de Lannoy, D.K. Lee, and G.A. Higgins A back translation of pregabalin and carbamazepine against evoked and non-evoked endpoints in the rat spared nerve injury model of neuropathic pain Neuropharmacology 73 2013 204 215
20. M.L. Prins, A. Hales, M. Reger, C.C. Giza, and D.A. Hovda Repeat traumatic brain injury in the juvenile rat is associated with increased axonal injury and cognitive impairments Dev. Neurosci. 32 2010 510 518
21. E. Bunster, and R.K. Mayer An improved method of parabiosis Anat. Rec. 57 1933 339 343
22. C. Nasca, R. Orlando, M. Marchiafava, P. Boldrini, G. Battaglia, S. Scaccianoce, F. Matrisciano, A. Pittaluga, and F. Nicoletti Exposure to predator odor and resulting anxiety enhances the expression of the α2δ subunit of voltage-sensitive calcium channels in the amygdala J. Neurochem. 125 2013 649 656
23. D.N. Xanthos, and J. Sandkühler Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activity Nat. Rev. Neurosci. 15 2014 43 53
24. W.J. Streit, R.E. Mrak, and W.S. Griffin Microglia and neuroinflammation: a pathological perspective J. Neuroinflammation 1 2004 14
25. S. Lehnardt Innate immunity and neuroinflammation in the CNS: the role of microglia in toll-like receptor-mediated neuronal injury Glia 58 2010 253 263
26. C. Cunningham Microglia and neurodegeneration: the role of systemic inflammation Glia 61 2013 71 90
27. E. Polazzi, and A. Contestabile Reciprocal interactions between microglia and neurons: from survival to neuropathology Rev. Neurosci. 13 2012 221 242
28. M. Domercq, N. Vázquez-Villoldo, and C. Matute Neurotransmitter signaling in the pathophysiology of microglia Front. Cell. Neurosci. 7 2013 49
29. A. Davies, J. Hendrich, A.T. Van Minh, J. Wratten, L. Douglas, and A.C. Dolphin Functional biology of the α2δ subunits of voltage-gated calcium channels Trends Pharmacol. Sci. 28 2007 220 228
30. H. Wang, H. Sun, K. Della Penna, R.J. Benz, J. Xu, D.L. Gerhold, D.J. Holder, and K.S. Koblan Chronic neuropathic pain is accompanied by global changes in gene expression and shares pathobiology with neurodegenerative diseases Neuroscience 114 2002 529 546
31. H.F. Green, and Y.M. Nolan Inflammation and the developing brain: consequences for hippocampal neurogenesis and behavior Neurosci. Biobehav. Rev. 40 2014 20 34
32. V.H. Perry, and C. Holmes Microglial priming in neurodegenerative disease Nat. Rev. Neurol. 10 2014 217 224
33. S. Vacas, V. Degos, X. Feng, and M. Maze The neuroinflammatory response of postoperative cognitive decline Br. Med. Bull. 106 2013 161 178
34. P. Xie, T. Yu, X. Fu, Y. Tu, Y. Zou, S. Lui, X. Zhao, X. Huang, G.J. Kemp, and Q. Gong Altered functional connectivity in an aged rat model of postoperative cognitive dysfunction: a study using resting-state functional MRI PLoS One 8 2013 e64820
35. V. Fodale, L.B. Santamaria, D. Schifilliti, and P.K. Mandal Anaesthetics and postoperative cognitive dysfunction: a pathological mechanism mimicking Alzheimer's disease Anaesthesia 65 2010 388 395