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Volumn 311, Issue 1, 2016, Pages R115-R123

Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca2+ influx in response to IL-6

Author keywords

Glucagon like peptide 1; Hindbrain; IL 6; IL 6R ; Preproglucagon

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; CALCIUM; GLUCAGON LIKE PEPTIDE 1; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR ALPHA; NEURON SPECIFIC NUCLEAR PROTEIN; PREPROGLUCAGON; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN-6 RECEPTOR ALPHA; INTERLEUKIN-6, MOUSE; NERVE PROTEIN; NEUN PROTEIN, MOUSE; NUCLEAR PROTEIN; PROGLUCAGON;

EID: 84984659300     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00383.2015     Document Type: Article
Times cited : (20)

References (41)
  • 1
    • 33751191841 scopus 로고    scopus 로고
    • Role of neuropeptides in appetite regulation and obesity—a review
    • Arora S, Anubhuti. Role of neuropeptides in appetite regulation and obesity—a review. Neuropeptides 40: 375-401, 2006.
    • (2006) Neuropeptides , vol.40 , pp. 375-401
    • Arora, S.1
  • 2
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio LL, Drucker DJ. Biology of incretins: GLP-1 and GIP. Gastroenterology 132: 2131-2125, 2007.
    • (2007) Gastroenterology , vol.132 , pp. 2131
    • Baggio, L.L.1    Drucker, D.J.2
  • 4
    • 0024532757 scopus 로고
    • A molecular basis for bidirectional communication between the immune and neuroendocrine systems
    • Blalock JE. A molecular basis for bidirectional communication between the immune and neuroendocrine systems. Physiol Rev 69: 1989.
    • (1989) Physiol Rev , pp. 69
    • Blalock, J.E.1
  • 5
    • 0024487876 scopus 로고
    • Area postrema: Chemoreceptor circumventricular organ of the medulla oblongata
    • Borison HL. Area postrema: Chemoreceptor circumventricular organ of the medulla oblongata. Progr Neurobiol 32: 351-390, 1989.
    • (1989) Progr Neurobiol , vol.32 , pp. 351-390
    • Borison, H.L.1
  • 6
    • 0034307162 scopus 로고    scopus 로고
    • Experimental cancer cachexia: The role of host-derived cytokines interleukin (IL)-6, IL-12, interferon-gamma, and tumor necrosis factor evaluated in gene knockout, tumor-bearing mice on C57/BL background and eicosanoid-dependent cachexia
    • Cahlin C, Körner A, Axelsson H, Wang W, Lundholm K, Svanberg E. Experimental cancer cachexia: the role of host-derived cytokines interleukin (IL)-6, IL-12, interferon-gamma, and tumor necrosis factor evaluated in gene knockout, tumor-bearing mice on C57/BL background and eicosanoid-dependent cachexia. Cancer Res 60: 5488-5493, 2000.
    • (2000) Cancer Res , vol.60 , pp. 5488-5493
    • Cahlin, C.1    Körner, A.2    Axelsson, H.3    Wang, W.4    Lundholm, K.5    Svanberg, E.6
  • 8
    • 0346688788 scopus 로고    scopus 로고
    • Multiple sclerosis: Cytokine receptors on oligodendrocytes predict innate regulation
    • Cannella B, Raine CS. Multiple sclerosis: Cytokine receptors on oligodendrocytes predict innate regulation. Ann Neurol 55: 46-57, 2004.
    • (2004) Ann Neurol , vol.55 , pp. 46-57
    • Cannella, B.1    Raine, C.S.2
  • 9
    • 0033836856 scopus 로고    scopus 로고
    • Circulating interleukin-6 mediates the febrile response to localised inflammation in rats
    • Cartmell T, Poole S, Turnbull AV, Rothwell NJ, Luheshi GN. Circulating interleukin-6 mediates the febrile response to localised inflammation in rats. J Physiol 526: 653-661, 2000.
    • (2000) J Physiol , vol.526 , pp. 653-661
    • Cartmell, T.1    Poole, S.2    Turnbull, A.V.3    Rothwell, N.J.4    Luheshi, G.N.5
  • 10
    • 33845998516 scopus 로고    scopus 로고
    • The role of gut hormones in glucose homeostasis
    • Drucker DJ. The role of gut hormones in glucose homeostasis. J Clin Invest 117: 24-32, 2007.
    • (2007) J Clin Invest , vol.117 , pp. 24-32
    • Drucker, D.J.1
  • 13
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nat Med 395: 763-770, 1998.
    • (1998) Nat Med , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 14
    • 84865714588 scopus 로고    scopus 로고
    • Hindbrain neurons as an essential hub in the neuroanatomically distributed control of energy balance
    • Grill HJ, Hayes MR. Hindbrain neurons as an essential hub in the neuroanatomically distributed control of energy balance. Cell Metab 16: 296-309, 2012.
    • (2012) Cell Metab , vol.16 , pp. 296-309
    • Grill, H.J.1    Hayes, M.R.2
  • 16
    • 77955369748 scopus 로고    scopus 로고
    • Leptin directly depolarizes preproglucagon neurons in the nucleus tractus solitarius: Electrical properties of glucagon-like peptide 1 neurons
    • Hisadome K, Reimann F, Gribble FM, Trapp S. Leptin directly depolarizes preproglucagon neurons in the nucleus tractus solitarius: electrical properties of glucagon-like peptide 1 neurons. Diabetes 59: 1890-1898, 2010.
    • (2010) Diabetes , vol.59 , pp. 1890-1898
    • Hisadome, K.1    Reimann, F.2    Gribble, F.M.3    Trapp, S.4
  • 18
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • Holst JJ. The physiology of glucagon-like peptide 1. Physiol Rev 87: 1409-1439, 2007.
    • (2007) Physiol Rev , vol.87 , pp. 1409-1439
    • Holst, J.J.1
  • 19
    • 84910028337 scopus 로고    scopus 로고
    • Therapies for inter-relating diabetes and obesity—GLP-1 and obesity
    • Iepsen EW, Torekov SS, Holst JJ. Therapies for inter-relating diabetes and obesity—GLP-1 and obesity. Expert Opin Pharmacother 15: 2487-2500, 2014.
    • (2014) Expert Opin Pharmacother , vol.15 , pp. 2487-2500
    • Iepsen, E.W.1    Torekov, S.S.2    Holst, J.J.3
  • 21
    • 84931097462 scopus 로고    scopus 로고
    • Amylin-induced central IL-6 production enhances ventromedial hypothalamic leptin signaling
    • LeFoll C, Johnson MD, Dunn-Meynell AA, Boyle CN, Lutz TA, Levin BE. Amylin-induced central IL-6 production enhances ventromedial hypothalamic leptin signaling. Diabetes 64: 1621-1631, 2015.
    • (2015) Diabetes , vol.64 , pp. 1621-1631
    • Lefoll, C.1    Johnson, M.D.2    Dunn-Meynell, A.A.3    Boyle, C.N.4    Lutz, T.A.5    Levin, B.E.6
  • 22
    • 0037049259 scopus 로고    scopus 로고
    • Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight reduction in rats
    • Li G, Klein RL, Matheny M, King MA, Meyer EM, Scarpace PJ. Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight reduction in rats. Neuroscience 115: 879-889, 2002.
    • (2002) Neuroscience , vol.115 , pp. 879-889
    • Li, G.1    Klein, R.L.2    Matheny, M.3    King, M.A.4    Meyer, E.M.5    Scarpace, P.J.6
  • 23
    • 79953189360 scopus 로고    scopus 로고
    • Preproglucagon neurons project widely to autonomic control areas in the mouse brain
    • Llewellyn-Smith IJ, Reimann F, Gribble FM, Trapp S. Preproglucagon neurons project widely to autonomic control areas in the mouse brain. Neuroscience 28: 111-121, 2011.
    • (2011) Neuroscience , vol.28 , pp. 111-121
    • Llewellyn-Smith, I.J.1    Reimann, F.2    Gribble, F.M.3    Trapp, S.4
  • 25
    • 33645942122 scopus 로고    scopus 로고
    • Role of the JAKs/STATs pathway in the intracellular calcium changes induced by interleukin-6 in hippocampal neurons
    • Orellana DI, Quintanilla RA, Gonzalez-Billault C, Maccioni RB. Role of the JAKs/STATs pathway in the intracellular calcium changes induced by interleukin-6 in hippocampal neurons. Neurotox Res 8: 295-304, 2005.
    • (2005) Neurotox Res , vol.8 , pp. 295-304
    • Orellana, D.I.1    Quintanilla, R.A.2    Gonzalez-Billault, C.3    Maccioni, R.B.4
  • 35
    • 0141675985 scopus 로고    scopus 로고
    • Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects
    • Stenlöf K, Wernstedt I, Fjällman T, Wallenius V, Wallenius K, Jansson JO. Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects. J Clin Endocrinol Metab 88: 4379-4383, 2003.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4379-4383
    • Stenlöf, K.1    Wernstedt, I.2    Fjällman, T.3    Wallenius, V.4    Wallenius, K.5    Jansson, J.O.6
  • 36
    • 0026689535 scopus 로고
    • Evidence for the involvement of interleukin 6 in experimental cancer cachexia
    • Strassmann G, Fong M, Kenney JS, Jacob CO. Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J Clin Invest 89: 1681-1684, 1992.
    • (1992) J Clin Invest , vol.89 , pp. 1681-1684
    • Strassmann, G.1    Fong, M.2    Kenney, J.S.3    Jacob, C.O.4
  • 40
    • 0033304589 scopus 로고    scopus 로고
    • Interleukin-6 is a needed proinflammatory cytokine in the prolonged neural activity and transcriptional activation of corticotropin-releasing factor during endotoxemia
    • Vallières L, Rivest S. Interleukin-6 is a needed proinflammatory cytokine in the prolonged neural activity and transcriptional activation of corticotropin-releasing factor during endotoxemia. Endocrinology 140: 3890-3903, 1999.
    • (1999) Endocrinology , vol.140 , pp. 3890-3903
    • Vallières, L.1    Rivest, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.