메뉴 건너뛰기




Volumn 6, Issue SUPPL. 2, 2013, Pages 249-254

Saponins from Solanum anguivi Lam. fruit exhibit in vitro and in vivo antioxidant activities in alloxan-induced oxidative stress

Author keywords

Alloxan; Antioxidant activity; Catalase; Diabetes; MDA; Medicinal plants; Saponin; Solanum anguivi fruit; Superoxide dismutase

Indexed keywords

2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); ALLOXAN; CATALASE; MALONALDEHYDE; SAPONIN; SUPEROXIDE DISMUTASE;

EID: 84984577954     PISSN: 09742441     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (18)

References (49)
  • 1
    • 65549116046 scopus 로고    scopus 로고
    • Reactive Oxygen Species, Cancer and Anti-Cancer Therapies
    • Manda G, Nechifor MT, Neagu TM. Reactive Oxygen Species, Cancer and Anti-Cancer Therapies. Curr Chemic Bio. 2009; 3: 342-366.
    • (2009) Curr Chemic Bio. , vol.3 , pp. 342-366
    • Manda, G.1    Nechifor, M.T.2    Neagu, T.M.3
  • 2
    • 0242509897 scopus 로고    scopus 로고
    • Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies
    • Amarowicz R, Pegg RB, Rahimi-Moghaddam P, Barl B, Weil JA. Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies. Food Chem. 2004; 84: 551-562.
    • (2004) Food Chem. , vol.84 , pp. 551-562
    • Amarowicz, R.1    Pegg, R.B.2    Rahimi-Moghaddam, P.3    Barl, B.4    Weil, J.A.5
  • 4
    • 0030906870 scopus 로고    scopus 로고
    • Antioxidants and human disease: A general introduction
    • Halliwell B. Antioxidants and human disease: A general introduction. Nutri Rev. 1997; 55: S44-S52.
    • (1997) Nutri Rev. , vol.55
    • Halliwell, B.1
  • 5
    • 84870448548 scopus 로고    scopus 로고
    • Reactive oxygen species, oxidative damage, and antioxidative defense mechanism in plants under stressful conditions
    • doi:10.1155/2012/217037
    • Sharma P, Jha AB, Dubey RS, Pessarakli M. Reactive oxygen species, oxidative damage, and antioxidative defense mechanism in plants under stressful conditions. J Botan. 2012; 217037:1-26. doi:10.1155/2012/217037.
    • (2012) J Botan. , pp. 1-26
    • Sharma, P.1    Jha, A.B.2    Dubey, R.S.3    Pessarakli, M.4
  • 6
    • 0037077387 scopus 로고    scopus 로고
    • Antioxidative properties of cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid
    • Valentão P, Fernandes E, Carvalho F, Andrade PB, Seabra RM, Bastos ML. Antioxidative properties of cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid. J Agric Food Chem. 2002; 50: 4989-4993.
    • (2002) J Agric Food Chem. , vol.50 , pp. 4989-4993
    • Valentão, P.1    Fernandes, E.2    Carvalho, F.3    Andrade, P.B.4    Seabra, R.M.5    Bastos, M.L.6
  • 7
    • 0347753692 scopus 로고    scopus 로고
    • Oxidative stress as a therapeutic target in diabetes: Revisiting the controversy
    • Wiernsperger NF. Oxidative stress as a therapeutic target in diabetes: revisiting the controversy. Diabetes Metab. 2003; 29: 579-585.
    • (2003) Diabetes Metab. , vol.29 , pp. 579-585
    • Wiernsperger, N.F.1
  • 9
    • 34548313690 scopus 로고    scopus 로고
    • Oxidants and antioxidants revisited. New concepts of oxidative stress
    • Packer L, Cadenas E. Oxidants and antioxidants revisited. New concepts of oxidative stress. Free Radic Res. 2007; 41: 951-2.
    • (2007) Free Radic Res. , vol.41 , pp. 951-952
    • Packer, L.1    Cadenas, E.2
  • 11
    • 34447283547 scopus 로고    scopus 로고
    • Hyperglicemia induced oxidative stress in type-1 and type-2 diabetic patients with and without nephropathy
    • Dave GS, Kalia K. Hyperglicemia induced oxidative stress in type-1 and type-2 diabetic patients with and without nephropathy. Cell Molecul Bio. 2007; 53: 68-78.
    • (2007) Cell Molecul Bio. , vol.53 , pp. 68-78
    • Dave, G.S.1    Kalia, K.2
  • 13
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature. 2001; 414: 813-20.
    • (2001) Nature. , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 14
    • 0035691617 scopus 로고    scopus 로고
    • The mechanism of alloxan and streptozotocin action in β-cells of the rat pancreas
    • Szkudelski T. The mechanism of alloxan and streptozotocin action in β-cells of the rat pancreas. Physiol Res. 2001; 50: 537-546.
    • (2001) Physiol Res. , vol.50 , pp. 537-546
    • Szkudelski, T.1
  • 15
    • 0034544962 scopus 로고    scopus 로고
    • Contrasting effects of alloxan on islets and single mouse pancreatic β-cells
    • Drews G, Kramer C, Dufer M, Drews PK. Contrasting effects of alloxan on islets and single mouse pancreatic β-cells. Biochem J. 2000; 352: 389-397.
    • (2000) Biochem J. , vol.352 , pp. 389-397
    • Drews, G.1    Kramer, C.2    Dufer, M.3    Drews, P.K.4
  • 16
    • 31144441711 scopus 로고    scopus 로고
    • A study on the in vitro antioxidant activity of juniper (Juniperus communis L.) seeds extracts
    • Elmastas M, Gülçin I, Beydemir S, Küfreviolu O, Aboul-Enein HY. A study on the in vitro antioxidant activity of juniper (Juniperus communis L.) seeds extracts. Anal Lett. 2006; 39: 47-65.
    • (2006) Anal Lett. , vol.39 , pp. 47-65
    • Elmastas, M.1    Gülçin, I.2    Beydemir, S.3    Küfreviolu, O.4    Aboul-Enein, H.Y.5
  • 18
    • 84872799123 scopus 로고    scopus 로고
    • Aqueous extract of African Egg Plant inhibit Fe2+ and SNP induced lipid peroxidation in Rat's brain-In vitro
    • Elekofehinti OO, Kade IJ. Aqueous extract of African Egg Plant inhibit Fe2+ and SNP induced lipid peroxidation in Rat's brain-In vitro. Der Pharma Lett. 2012; 4: 1352-1359.
    • (2012) Der Pharma Lett. , vol.4 , pp. 1352-1359
    • Elekofehinti, O.O.1    Kade, I.J.2
  • 19
    • 77949586035 scopus 로고    scopus 로고
    • Comparative Antioxidant Properties of Water Extracts from Different Parts of Beefsteak Plant (Perilla frutescens)
    • Hung JC, Jong TK, En-Shyh L. Comparative Antioxidant Properties of Water Extracts from Different Parts of Beefsteak Plant (Perilla frutescens). J Food Drug Ana. 2009; 17: 489-496.
    • (2009) J Food Drug Ana. , vol.17 , pp. 489-496
    • Hung, J.C.1    Jong, T.K.2    En-Shyh, L.3
  • 20
    • 84984570926 scopus 로고    scopus 로고
    • Effect of saponin from Solanum anguivi Lam. fruit on heart and kidney superoxide dismutase, catalase and malondialdehyde in rat
    • Elekofehinti OO, Adanlawo IG, Fakoya A, Saliu JA, Sodehinde SA. Effect of saponin from Solanum anguivi Lam. fruit on heart and kidney superoxide dismutase, catalase and malondialdehyde in rat. Curr Res J Bio Sci. 2012; 4: 530-533.
    • (2012) Curr Res J Bio Sci. , vol.4 , pp. 530-533
    • Elekofehinti, O.O.1    Adanlawo, I.G.2    Fakoya, A.3    Saliu, J.A.4    Sodehinde, S.A.5
  • 21
    • 84864020529 scopus 로고    scopus 로고
    • Saponins from Solanum anguivi fruits exhibit hypolipidemic potential in Rattus novergicus
    • Elekofehinti OO, Adanlawo IG, Saliu JA, Sodehinde SA. Saponins from Solanum anguivi fruits exhibit hypolipidemic potential in Rattus novergicus. Der Pharma Lett. 2012; 4: 811-814.
    • (2012) Der Pharma Lett. , vol.4 , pp. 811-814
    • Elekofehinti, O.O.1    Adanlawo, I.G.2    Saliu, J.A.3    Sodehinde, S.A.4
  • 22
    • 84879165372 scopus 로고    scopus 로고
    • Solanum anguivi saponins inhibit basal erythropoiesis in Rattus novergicus
    • Elekofehinti OO, Adanlawo IG, Fakoya A. 2012 Solanum anguivi saponins inhibit basal erythropoiesis in Rattus novergicus. Asian J Pharm Health Sci. 2012; 2: 416-419.
    • (2012) Asian J Pharm Health Sci. , vol.2 , pp. 416-419
    • Elekofehinti, O.O.1    Adanlawo, I.G.2    Fakoya, A.3
  • 23
    • 84864003465 scopus 로고    scopus 로고
    • Effect of chronic administration of saponin extract from the fruits of Solanum anguivi Lam. on alkaline phosphatase activities of some rat tissues
    • Adanlawo IG, Akanji MA. Effect of chronic administration of saponin extract from the fruits of Solanum anguivi Lam. on alkaline phosphatase activities of some rat tissues. Nigerian J Biochem molecu Bio. 2003; 18: 59-62.
    • (2003) Nigerian J Biochem molecu Bio. , vol.18 , pp. 59-62
    • Adanlawo, I.G.1    Akanji, M.A.2
  • 25
    • 84863401580 scopus 로고    scopus 로고
    • Antioxidant activities of Indigofera cassioides Rottl. Using various in vitro assay models
    • Kumar RS, Rajkapoor B, Perumal P. Antioxidant activities of Indigofera cassioides Rottl. Using various in vitro assay models. Asian Pac J Trop Biomed. 2012; 2: 256-261.
    • (2012) Asian Pac J Trop Biomed. , vol.2 , pp. 256-261
    • Kumar, R.S.1    Rajkapoor, B.2    Perumal, P.3
  • 26
    • 84984541429 scopus 로고    scopus 로고
    • Krebs cycle intermediates modulate thiobarbituric reactive species (TBARS) production in Rat Brain In vitro
    • Puntel RL, Nogueira CW, Rocha JBT. Krebs cycle intermediates modulate thiobarbituric reactive species (TBARS) production in Rat Brain In vitro. Neurochem Res. 2005; 30: 225-235.
    • (2005) Neurochem Res. , vol.30 , pp. 225-235
    • Puntel, R.L.1    Nogueira, C.W.2    Rocha, J.B.T.3
  • 27
    • 0018384650 scopus 로고
    • Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi H, Yagi K. Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979; 95: 351-358.
    • (1979) Anal Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, H.2    Yagi, K.3
  • 28
    • 0018128936 scopus 로고
    • An improved spectrophotomeric assay for superoxide dismutase based on epinephrine autoxidation
    • Sun M, Zigman S. An improved spectrophotomeric assay for superoxide dismutase based on epinephrine autoxidation. Anals of Biochem. 1978; 90: 81-89.
    • (1978) Anals of Biochem. , vol.90 , pp. 81-89
    • Sun, M.1    Zigman, S.2
  • 29
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Meth in Enzymol. 1984; 105: 121-126.
    • (1984) Meth in Enzymol. , vol.105 , pp. 121-126
    • Aebi, H.1
  • 31
    • 0017184389 scopus 로고
    • A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
    • Bradford M. A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding. Anal Biochem. 1979; 72: 248.
    • (1979) Anal Biochem. , vol.72 , pp. 248
    • Bradford, M.1
  • 32
    • 77954997237 scopus 로고    scopus 로고
    • Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet induced obesed rats
    • Eu CH, Lim WY, Ton SH, Kadir KA. Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet induced obesed rats. Lipids health Diseas. 2010; 9: 1-9.
    • (2010) Lipids health Diseas. , vol.9 , pp. 1-9
    • Eu, C.H.1    Lim, W.Y.2    Ton, S.H.3    Kadir, K.A.4
  • 34
    • 67650689053 scopus 로고    scopus 로고
    • Effect of saponins from Helicteres isora on lipid and glucose metabolism regulating genes expression
    • Bhavsar SK, Satinder S, Suresh G, Mukul RJ, Dev DS. Effect of saponins from Helicteres isora on lipid and glucose metabolism regulating genes expression. J Ethnopharmacol. 2009; 124: 426-433.
    • (2009) J Ethnopharmacol. , vol.124 , pp. 426-433
    • Bhavsar, S.K.1    Satinder, S.2    Suresh, G.3    Mukul, R.J.4    Dev, D.S.5
  • 35
    • 84867302330 scopus 로고    scopus 로고
    • Dietary Saponins of Sea Cucumber Ameliorate Obesity, Hepatic Steatosis, and Glucose Intolerance in High-Fat Diet-Fed Mice
    • Hu X, Zhaojie L, Yong X, Jie X, Changhu X, Jingfeng W, Yuming W. Dietary Saponins of Sea Cucumber Ameliorate Obesity, Hepatic Steatosis, and Glucose Intolerance in High-Fat Diet-Fed Mice. J Med Food. 2012; 15: 909-916.
    • (2012) J Med Food. , vol.15 , pp. 909-916
    • Hu, X.1    Zhaojie, L.2    Yong, X.3    Jie, X.4    Changhu, X.5    Jingfeng, W.6    Yuming, W.7
  • 36
    • 79955584588 scopus 로고    scopus 로고
    • Antioxidant potential of Idigofera linnaei Ali.-an In vitro study
    • Kumar RS, Rajkapoor B, Perumal P. antioxidant potential of Idigofera linnaei Ali.-an In vitro study. Pharmacologyonlin. 2011; 1: 710-720.
    • (2011) Pharmacologyonlin. , vol.1 , pp. 710-720
    • Kumar, R.S.1    Rajkapoor, B.2    Perumal, P.3
  • 37
    • 78651383851 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo
    • Huang MH, Huang SS, Wang BS, Wu CH, Sheu MJ, Hou WC, et al. Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo. J Ethnopharmacol. 2011; 133: 743-750.
    • (2011) J Ethnopharmacol. , vol.133 , pp. 743-750
    • Huang, M.H.1    Huang, S.S.2    Wang, B.S.3    Wu, C.H.4    Sheu, M.J.5    Hou, W.C.6
  • 39
    • 84874734708 scopus 로고    scopus 로고
    • Antioxidant and antihepatotoxic activities of ethanolic extract of Solanum torvum
    • Bhuvaneswari. B, Hari R, Suguna VR. Antioxidant and antihepatotoxic activities of ethanolic extract of Solanum torvum. Asian J Pharm Clin Res. 202; 5:147-150.
    • (2002) Asian J Pharm Clin Res. , vol.5 , pp. 147-150
    • Bhuvaneswari, B.1    Hari, R.2    Suguna, V.R.3
  • 41
    • 84879132732 scopus 로고    scopus 로고
    • Heavy metals distribution and lipid profile in the stomach of cow grazed in Akungba-Akoko, Ondo State
    • DOI: 10.5897/AJBR12.011
    • Elekofehinti OO, Omotuyi IO, Olaremu AG, Abayomi TG. Heavy metals distribution and lipid profile in the stomach of cow grazed in Akungba-Akoko, Ondo State, Nigeria. African J Biochem Res. 2012; 6: 146-149. DOI: 10.5897/AJBR12.011.
    • (2012) Nigeria. African J Biochem Res. , vol.6 , pp. 146-149
    • Elekofehinti, O.O.1    Omotuyi, I.O.2    Olaremu, A.G.3    Abayomi, T.G.4
  • 42
    • 41349120026 scopus 로고    scopus 로고
    • Intracellular Iron Transport and Storage: From Molecular Mechanisms to Health Implications
    • doi:10.1089/ars.2007.1893
    • Mackenzie EL, Iwasaki K, Tsuji Y. Intracellular Iron Transport and Storage: From Molecular Mechanisms to Health Implications. Antioxidants Redox Signal. 2008; 10: 997-1030. doi:10.1089/ars.2007.1893.
    • (2008) Antioxidants Redox Signal. , vol.10 , pp. 997-1030
    • McKenzie, E.L.1    Iwasaki, K.2    Tsuji, Y.3
  • 43
    • 84984549279 scopus 로고    scopus 로고
    • Hot pepper (Capsicum annuum, Tepin and Capsicum chinese, Habanero) prevents Fe2+-induced lipid peroxidation in Brain-In vitro
    • Oboh G, Puntel RL, Rocha JBT. Hot pepper (Capsicum annuum, Tepin and Capsicum chinese, Habanero) prevents Fe2+-induced lipid peroxidation in Brain-In vitro. Food Chem. 2007; 102: 178-185.
    • (2007) Food Chem. , vol.102 , pp. 178-185
    • Oboh, G.1    Puntel, R.L.2    Rocha, J.B.T.3
  • 44
    • 0000840182 scopus 로고
    • An enzyme based theory of obigate anaerobiosis, the physiological functions of superoxide dismutase
    • Mc-Crod JM, Keele BB, Fridovich I. An enzyme based theory of obigate anaerobiosis, the physiological functions of superoxide dismutase. Proce Nat Acad Sci. 1976; 68:1024.
    • (1976) Proce Nat Acad Sci. , vol.68 , pp. 1024
    • Mc-Crod, J.M.1    Keele, B.B.2    Fridovich, I.3
  • 45
    • 84878352217 scopus 로고    scopus 로고
    • Antihyperglycemic and antioxidant activity of water extract from Anoectochilus roxburghii in experimental diabetes
    • doi:10.1016/j.etp.2012.02.003
    • Cui SC, Yu J, Zhang XH, Cheng MZ, Yang LW, XU JY. Antihyperglycemic and antioxidant activity of water extract from Anoectochilus roxburghii in experimental diabetes. Exp Toxicol Pathol. 2012; doi:10.1016/j.etp.2012.02.003.
    • (2012) Exp Toxicol Pathol.
    • Cui, S.C.1    Yu, J.2    Zhang, X.H.3    Cheng, M.Z.4    Yang, L.W.5    Xu, J.Y.6
  • 46
    • 0032992972 scopus 로고    scopus 로고
    • Antioxidant activity of active tannoid principles of Emblica officinalis (amla)
    • Arunabh B, Abhijit C, Ghosal S, Battacharya SK. Antioxidant activity of active tannoid principles of Emblica officinalis (amla). Indian J Experiment Bio. 1999; 37: 676-80.
    • (1999) Indian J Experiment Bio. , vol.37 , pp. 676-680
    • Arunabh, B.1    Abhijit, C.2    Ghosal, S.3    Battacharya, S.K.4
  • 48
    • 50449122962 scopus 로고
    • The mechanism of catalase action in steady state analysis
    • Chance B, Stein DS, Roughton RJW. The mechanism of catalase action in steady state analysis. Arch Biochem Biophy. 1952; 37: 301-39.
    • (1952) Arch Biochem Biophy. , vol.37 , pp. 301-339
    • Chance, B.1    Stein, D.S.2    Roughton, R.J.W.3
  • 49
    • 0018835727 scopus 로고
    • Glutathione peroxidase: Effect of superoxide, hydroxyl and bromine free radicals on enzymic activity
    • Searle AJ, Wilson RL. Glutathione peroxidase: effect of superoxide, hydroxyl and bromine free radicals on enzymic activity. Int J Radiat Bio Rel Stud Phy Chem Med. 1980; 37: 213-7.
    • (1980) Int J Radiat Bio Rel Stud Phy Chem Med. , vol.37 , pp. 213-217
    • Searle, A.J.1    Wilson, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.