Phospholipase C-ε signaling mediates endothelial cell inflammation and barrier disruption in acute lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 311, Issue 2, 2016, Pages 517-524

  Bijli, Kaiser M ^a   Fazal, Fabeha ^a   Slavin, Spencer A ^a   Leonard, Antony ^a   Grose, Valerie ^a   Alexander, William B ^a   Smrcka, Alan V ^a   Rahman, Arshad ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Adhesion molecules; Endothelial cells; Lung inflammation; Signal transduction; Transcription factors

Indexed keywords

ACTIN; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; PHORBOL 12 ACETATE 13 MYRISTATE; PHOSPHOLIPASE C; PHOSPHOLIPASE C EPSILON; THROMBIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULAR ENDOTHELIAL CADHERIN; CADHERIN; LEUKOCYTE ANTIGEN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE;

ACUTE LUNG INJURY; ADHERENS JUNCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXPERIMENTAL MODEL; GENE; LUNG; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY VASCULITIS; STRESS FIBER; ANIMAL; C57BL MOUSE; CAPILLARY PERMEABILITY; CELL CULTURE; ENZYMOLOGY; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; VASCULARIZATION; VASCULITIS;

ACUTE LUNG INJURY; ANIMALS; ANTIGENS, CD; CADHERINS; CAPILLARY PERMEABILITY; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMANS; LUNG; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; PHOSPHOINOSITIDE PHOSPHOLIPASE C; SIGNAL TRANSDUCTION; STRESS FIBERS; VASCULITIS;

EID: 84983755325     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00069.2016     Document Type: Article

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