Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 5, 2015, Pages 778-791

  Birukova, Anna A ^a   Meng, Fanyong ^a   Tian, Yufeng ^a   Meliton, Angelo ^a   Sarich, Nicolene ^a   Quilliam, Lawrence A ^b   Birukov, Konstantin G ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytoskeleton; Endothelium; Inflammation; Lung; Permeability

Indexed keywords

BERAPROST; EVANS BLUE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTACYCLIN; RAP1 PROTEIN; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; VASCULAR ENDOTHELIAL CADHERIN; 8-(4-CHLORO-PHENYLTHIO)-2'-O-METHYLADENOSINE-3'-5'-CYCLIC MONOPHOSPHATE; ACTIN BINDING PROTEIN; AFADIN; ANTITHROMBOCYTIC AGENT; CYCLIC AMP; EPAC PROTEIN, MOUSE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; ICAM1 PROTEIN, MOUSE; INTERCELLULAR ADHESION MOLECULE 1;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CELL COUNT; CELL JUNCTION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ENDOTHELIUM; LUNG LAVAGE; LUNG VASCULAR ENDOTHELIAL BARRIER; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CHEMICALLY INDUCED; DRUG EFFECTS; ENDOTHELIUM CELL; GENETICS; IMMUNOBLOTTING; KNOCKOUT MOUSE; METABOLISM; RNA INTERFERENCE; VASCULAR ENDOTHELIUM;

MURINAE; MUS;

ACUTE LUNG INJURY; ANIMALS; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CYCLIC AMP; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; EPOPROSTENOL; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNOBLOTTING; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLATELET AGGREGATION INHIBITORS; RAP1 GTP-BINDING PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 84922572970     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.12.016     Document Type: Article

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