Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and ras-associating domains of phospholipase Cε

Journal of Biological Chemistry

Volumn 290, Issue 44, 2015, Pages 26776-26783

  Dusaban, Stephanie S ^a,b   Kunkel, Maya T ^a   Smrcka, Alan V ^c   Brown, Joan Heller ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; ENZYMES; GENE EXPRESSION REGULATION; GENES;

GENE DELETION; INFLAMMATORY GENE EXPRESSIONS; PATHOPHYSIOLOGICAL; PHOSPHOLIPASE C; REGULATORY MECHANISM;

GENE EXPRESSION;

BREFELDIN A; CELL PROTEIN; CYCLOOXYGENASE 2; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 6; PHOSPHOLIPASE C; PHOSPHOLIPASE C EPSILON; PROTEIN KINASE D; PROTEIN TYROSINE PHOSPHATASE; RAP1 PROTEIN; RAS ASSOCIATING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBIN; UNCLASSIFIED DRUG; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INOSITOL 1,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL COMPARTMENTALIZATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME KINETICS; GENE EXPRESSION; GENE INDUCTION; GOLGI COMPLEX; IL 6 GENE; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEWBORN; PRIMARY CELL CULTURE; PROTEIN TERTIARY STRUCTURE; TRANSGENIC MOUSE;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELL COMPARTMENTATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION; GOLGI APPARATUS; INFLAMMATION; INOSITOL 1,4,5-TRISPHOSPHATE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHOINOSITIDE PHOSPHOLIPASE C; PRIMARY CELL CULTURE; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; RAP1 GTP-BINDING PROTEINS; RAS-GRF1; SIGNAL TRANSDUCTION; THROMBIN;

EID: 84946094276     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.676098     Document Type: Article

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