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Volumn 116, Issue , 2016, Pages 107-119

A novel real time imaging platform to quantify macrophage phagocytosis

Author keywords

Inflammation; LPS; Macrophage; Phagocytosis

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; INTERLEUKIN 10; INTERLEUKIN 4; OPSONIN; ENDOTOXIN; ENDOTOXIN, ESCHERICHIA COLI; INTERLEUKIN DERIVATIVE;

EID: 84983732273     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2016.07.011     Document Type: Article
Times cited : (107)

References (66)
  • 2
    • 80355136629 scopus 로고    scopus 로고
    • Studying the mononuclear phagocyte system in the molecular age
    • [2] Chow, A., Brown, B.D., Merad, M., Studying the mononuclear phagocyte system in the molecular age. Nat. Rev. Immunol. 11:11 (2011), 788–798.
    • (2011) Nat. Rev. Immunol. , vol.11 , Issue.11 , pp. 788-798
    • Chow, A.1    Brown, B.D.2    Merad, M.3
  • 4
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • [4] Shimazu, R., Akashi, S., Ogata, H., Nagai, Y., Fukudome, K., Miyake, K., Kimoto, M., MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189:11 (1999), 1777–1782.
    • (1999) J. Exp. Med. , vol.189 , Issue.11 , pp. 1777-1782
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3    Nagai, Y.4    Fukudome, K.5    Miyake, K.6    Kimoto, M.7
  • 5
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • [5] Scaffidi, P., Misteli, T., Bianchi, M.E., Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418:6894 (2002), 191–195.
    • (2002) Nature , vol.418 , Issue.6894 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 7
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • [7] Shi, Y., Evans, J.E., Rock, K.L., Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425:6957 (2003), 516–521.
    • (2003) Nature , vol.425 , Issue.6957 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 8
    • 34248157158 scopus 로고    scopus 로고
    • Insights into immunoglobulin E receptor signaling from structurally defined ligands
    • [8] Holowka, D., Sil, D., Torigoe, C., Baird, B., Insights into immunoglobulin E receptor signaling from structurally defined ligands. Immunol. Rev. 217 (2007), 269–279.
    • (2007) Immunol. Rev. , vol.217 , pp. 269-279
    • Holowka, D.1    Sil, D.2    Torigoe, C.3    Baird, B.4
  • 9
    • 0028239549 scopus 로고
    • Physical and functional association of Src-related protein tyrosine kinases with Fc gamma RII in monocytic THP-1 cells
    • [9] Ghazizadeh, S., Bolen, J.B., Fleit, H.B., Physical and functional association of Src-related protein tyrosine kinases with Fc gamma RII in monocytic THP-1 cells. J. Biol. Chem. 269:12 (1994), 8878–8884.
    • (1994) J. Biol. Chem. , vol.269 , Issue.12 , pp. 8878-8884
    • Ghazizadeh, S.1    Bolen, J.B.2    Fleit, H.B.3
  • 10
    • 0028106837 scopus 로고
    • Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn
    • [10] Wang, A.V., Scholl, P.R., Geha, R.S., Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn. J. Exp. Med. 180:3 (1994), 1165–1170.
    • (1994) J. Exp. Med. , vol.180 , Issue.3 , pp. 1165-1170
    • Wang, A.V.1    Scholl, P.R.2    Geha, R.S.3
  • 11
    • 0027318774 scopus 로고
    • Association of immunoglobulin G Fc receptor II with Src-like protein-tyrosine kinase Fgr in neutrophils
    • [11] Hamada, F., Aoki, M., Akiyama, T., Toyoshima, K., Association of immunoglobulin G Fc receptor II with Src-like protein-tyrosine kinase Fgr in neutrophils. Proc. Natl. Acad. Sci. U.S.A. 90:13 (1993), 6305–6309.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , Issue.13 , pp. 6305-6309
    • Hamada, F.1    Aoki, M.2    Akiyama, T.3    Toyoshima, K.4
  • 15
    • 0028328732 scopus 로고
    • Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus
    • [15] Desjardins, M., Huber, L.A., Parton, R.G., Griffiths, G., Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus. J. Cell Biol. 124:5 (1994), 677–688.
    • (1994) J. Cell Biol. , vol.124 , Issue.5 , pp. 677-688
    • Desjardins, M.1    Huber, L.A.2    Parton, R.G.3    Griffiths, G.4
  • 17
    • 68049105101 scopus 로고    scopus 로고
    • Rab GTPases as coordinators of vesicle traffic
    • [17] Stenmark, H., Rab GTPases as coordinators of vesicle traffic. Nat. Rev. Mol. Cell Biol. 10:8 (2009), 513–525.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , Issue.8 , pp. 513-525
    • Stenmark, H.1
  • 18
    • 33644935227 scopus 로고    scopus 로고
    • The V-type H+ ATPase: molecular structure and function, physiological roles and regulation
    • [18] Beyenbach, K.W., Wieczorek, H., The V-type H+ ATPase: molecular structure and function, physiological roles and regulation. J. Exp. Biol. 209:Pt 4 (2006), 577–589.
    • (2006) J. Exp. Biol. , vol.209 , pp. 577-589
    • Beyenbach, K.W.1    Wieczorek, H.2
  • 19
    • 64749091309 scopus 로고    scopus 로고
    • Antimicrobial mechanisms of phagocytes and bacterial evasion strategies
    • [19] Flannagan, R.S., Cosio, G., Grinstein, S., Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nat. Rev. Microbiol. 7:5 (2009), 355–366.
    • (2009) Nat. Rev. Microbiol. , vol.7 , Issue.5 , pp. 355-366
    • Flannagan, R.S.1    Cosio, G.2    Grinstein, S.3
  • 20
    • 0033664277 scopus 로고    scopus 로고
    • Leukocyte antimicrobial peptides: multifunctional effector molecules of innate immunity
    • [20] Risso, A., Leukocyte antimicrobial peptides: multifunctional effector molecules of innate immunity. J. Leukoc. Biol. 68:6 (2000), 785–792.
    • (2000) J. Leukoc. Biol. , vol.68 , Issue.6 , pp. 785-792
    • Risso, A.1
  • 21
    • 78650718978 scopus 로고    scopus 로고
    • A method for generation of bone marrow-derived macrophages from cryopreserved mouse bone marrow cells
    • [21] Marim, F.M., Silveira, T.N., Lima, D.S. Jr., Zamboni, D.S., A method for generation of bone marrow-derived macrophages from cryopreserved mouse bone marrow cells. PLoS ONE, 5(12), 2010, e15263.
    • (2010) PLoS ONE , vol.5 , Issue.12 , pp. e15263
    • Marim, F.M.1    Silveira, T.N.2    Lima, D.S.3    Zamboni, D.S.4
  • 22
    • 0029048270 scopus 로고
    • Granulocyte/macrophage colony-stimulating factor is expressed and secreted in cultures of murine L929 cells
    • [22] Englen, M.D., Valdez, Y.E., Lehnert, N.M., Lehnert, B.E., Granulocyte/macrophage colony-stimulating factor is expressed and secreted in cultures of murine L929 cells. J. Immunol. Methods 184:2 (1995), 281–283.
    • (1995) J. Immunol. Methods , vol.184 , Issue.2 , pp. 281-283
    • Englen, M.D.1    Valdez, Y.E.2    Lehnert, N.M.3    Lehnert, B.E.4
  • 24
    • 84881506946 scopus 로고    scopus 로고
    • Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions
    • [24] van Wilgenburg, B., Browne, C., Vowles, J., Cowley, S.A., Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions. PLoS ONE, 8(8), 2013.
    • (2013) PLoS ONE , vol.8 , Issue.8
    • van Wilgenburg, B.1    Browne, C.2    Vowles, J.3    Cowley, S.A.4
  • 25
    • 84983763170 scopus 로고    scopus 로고
    • IncuCyte™ Background Fluorescence Technical Note. <>, (accessed 26.05.2016).
    • [25] ESSEN BioScience, IncuCyte™ Background Fluorescence Technical Note. < http://www.essenbioscience.com/media/uploads/files/8000-0265-A00_IncuCyte_Background_Fluorescence_Technical_Note.pdf>, (accessed 26.05.2016).
    • ESSEN BioScience1
  • 27
    • 84863172698 scopus 로고    scopus 로고
    • Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps
    • [27] Yan, J., Meng, X., Wancket, L.M., Lintner, K., Nelin, L.D., Chen, B., Francis, K.P., Smith, C.V., Rogers, L.K., Liu, Y., Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps. J. Immunol. 188:5 (2012), 2316–2327.
    • (2012) J. Immunol. , vol.188 , Issue.5 , pp. 2316-2327
    • Yan, J.1    Meng, X.2    Wancket, L.M.3    Lintner, K.4    Nelin, L.D.5    Chen, B.6    Francis, K.P.7    Smith, C.V.8    Rogers, L.K.9    Liu, Y.10
  • 28
    • 84923066197 scopus 로고    scopus 로고
    • Cyclo(Phe-Pro) produced by the human pathogen Vibrio vulnificus inhibits host innate immune responses through the NF-kappaB pathway
    • [28] Kim, K., Kim, N.J., Kim, S.Y., Kim, I.H., Kim, K.S., Lee, G.R., Cyclo(Phe-Pro) produced by the human pathogen Vibrio vulnificus inhibits host innate immune responses through the NF-kappaB pathway. Infect. Immun. 83:3 (2015), 1150–1161.
    • (2015) Infect. Immun. , vol.83 , Issue.3 , pp. 1150-1161
    • Kim, K.1    Kim, N.J.2    Kim, S.Y.3    Kim, I.H.4    Kim, K.S.5    Lee, G.R.6
  • 29
    • 77949834455 scopus 로고    scopus 로고
    • A nucleator arms race: cellular control of actin assembly
    • [29] Campellone, K.G., Welch, M.D., A nucleator arms race: cellular control of actin assembly. Nat. Rev. Mol. Cell Biol. 11:4 (2010), 237–251.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , Issue.4 , pp. 237-251
    • Campellone, K.G.1    Welch, M.D.2
  • 30
    • 0037178706 scopus 로고    scopus 로고
    • Role of formins in actin assembly: nucleation and barbed-end association
    • [30] Pruyne, D., Evangelista, M., Yang, C., Bi, E., Zigmond, S., Bretscher, A., Boone, C., Role of formins in actin assembly: nucleation and barbed-end association. Science 297:5581 (2002), 612–615.
    • (2002) Science , vol.297 , Issue.5581 , pp. 612-615
    • Pruyne, D.1    Evangelista, M.2    Yang, C.3    Bi, E.4    Zigmond, S.5    Bretscher, A.6    Boone, C.7
  • 31
    • 3342938063 scopus 로고    scopus 로고
    • Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis
    • [31] Hoppe, A.D., Swanson, J.A., Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis. Mol. Biol. Cell 15:8 (2004), 3509–3519.
    • (2004) Mol. Biol. Cell , vol.15 , Issue.8 , pp. 3509-3519
    • Hoppe, A.D.1    Swanson, J.A.2
  • 32
    • 0033790639 scopus 로고    scopus 로고
    • Involvement of the Arp2/3 complex in phagocytosis mediated by FcgammaR or CR3
    • [32] May, R.C., Caron, E., Hall, A., Machesky, L.M., Involvement of the Arp2/3 complex in phagocytosis mediated by FcgammaR or CR3. Nat. Cell Biol. 2:4 (2000), 246–248.
    • (2000) Nat. Cell Biol. , vol.2 , Issue.4 , pp. 246-248
    • May, R.C.1    Caron, E.2    Hall, A.3    Machesky, L.M.4
  • 33
    • 0034536206 scopus 로고    scopus 로고
    • Microtubule-dependent formation of podosomal adhesion structures in primary human macrophages
    • [33] Linder, S., Hufner, K., Wintergerst, U., Aepfelbacher, M., Microtubule-dependent formation of podosomal adhesion structures in primary human macrophages. J. Cell Sci. 113:Pt 23 (2000), 4165–4176.
    • (2000) J. Cell Sci. , vol.113 , pp. 4165-4176
    • Linder, S.1    Hufner, K.2    Wintergerst, U.3    Aepfelbacher, M.4
  • 34
    • 0026348650 scopus 로고
    • Determinants of the phagosomal pH in macrophages. In situ assessment of vacuolar H(+)-ATPase activity, counterion conductance, and H+ “leak”
    • [34] Lukacs, G.L., Rotstein, O.D., Grinstein, S., Determinants of the phagosomal pH in macrophages. In situ assessment of vacuolar H(+)-ATPase activity, counterion conductance, and H+ “leak”. J. Biol. Chem. 266:36 (1991), 24540–24548.
    • (1991) J. Biol. Chem. , vol.266 , Issue.36 , pp. 24540-24548
    • Lukacs, G.L.1    Rotstein, O.D.2    Grinstein, S.3
  • 35
    • 0025278076 scopus 로고
    • Phagocytosis mediated by three distinct Fc gamma receptor classes on human leukocytes
    • [35] Anderson, C.L., Shen, L., Eicher, D.M., Wewers, M.D., Gill, J.K., Phagocytosis mediated by three distinct Fc gamma receptor classes on human leukocytes. J. Exp. Med. 171:4 (1990), 1333–1345.
    • (1990) J. Exp. Med. , vol.171 , Issue.4 , pp. 1333-1345
    • Anderson, C.L.1    Shen, L.2    Eicher, D.M.3    Wewers, M.D.4    Gill, J.K.5
  • 36
    • 0026773636 scopus 로고
    • Macrophage cytoskeleton association with CR3 and CR4 regulates receptor mobility and phagocytosis of iC3b-opsonized erythrocytes
    • [36] Ross, G.D., Reed, W., Dalzell, J.G., Becker, S.E., Hogg, N., Macrophage cytoskeleton association with CR3 and CR4 regulates receptor mobility and phagocytosis of iC3b-opsonized erythrocytes. J. Leukoc. Biol. 51:2 (1992), 109–117.
    • (1992) J. Leukoc. Biol. , vol.51 , Issue.2 , pp. 109-117
    • Ross, G.D.1    Reed, W.2    Dalzell, J.G.3    Becker, S.E.4    Hogg, N.5
  • 37
    • 0032519011 scopus 로고    scopus 로고
    • C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets
    • [37] Nepomuceno, R.R., Tenner, A.J., C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets. J. Immunol. 160:4 (1998), 1929–1935.
    • (1998) J. Immunol. , vol.160 , Issue.4 , pp. 1929-1935
    • Nepomuceno, R.R.1    Tenner, A.J.2
  • 38
    • 0021080912 scopus 로고
    • Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes
    • [38] Wright, S.D., Silverstein, S.C., Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes. J. Exp. Med. 158:6 (1983), 2016–2023.
    • (1983) J. Exp. Med. , vol.158 , Issue.6 , pp. 2016-2023
    • Wright, S.D.1    Silverstein, S.C.2
  • 39
    • 78650588631 scopus 로고    scopus 로고
    • Coordination of Fc receptor signaling regulates cellular commitment to phagocytosis
    • [39] Zhang, Y., Hoppe, A.D., Swanson, J.A., Coordination of Fc receptor signaling regulates cellular commitment to phagocytosis. Proc. Natl. Acad. Sci. U.S.A. 107:45 (2010), 19332–19337.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , Issue.45 , pp. 19332-19337
    • Zhang, Y.1    Hoppe, A.D.2    Swanson, J.A.3
  • 40
    • 0344420075 scopus 로고    scopus 로고
    • Enhanced phagocytosis of Candida species mediated by opsonization with a recombinant human antibody single-chain variable fragment
    • [40] Wellington, M., Bliss, J.M., Haidaris, C.G., Enhanced phagocytosis of Candida species mediated by opsonization with a recombinant human antibody single-chain variable fragment. Infect. Immun. 71:12 (2003), 7228–7231.
    • (2003) Infect. Immun. , vol.71 , Issue.12 , pp. 7228-7231
    • Wellington, M.1    Bliss, J.M.2    Haidaris, C.G.3
  • 41
    • 0019810962 scopus 로고
    • Murine defense mechanism against Candida albicans infection. II. Opsonization, phagocytosis, and intracellular killing of C. albicans
    • [41] Kagaya, K., Fukazawa, Y., Murine defense mechanism against Candida albicans infection. II. Opsonization, phagocytosis, and intracellular killing of C. albicans. Microbiol. Immunol. 25:8 (1981), 807–818.
    • (1981) Microbiol. Immunol. , vol.25 , Issue.8 , pp. 807-818
    • Kagaya, K.1    Fukazawa, Y.2
  • 42
    • 0022641004 scopus 로고
    • Immune protection against foot-and-mouth disease virus studied using virus-neutralizing and non-neutralizing concentrations of monoclonal antibodies
    • [42] McCullough, K.C., Crowther, J.R., Butcher, R.N., Carpenter, W.C., Brocchi, E., Capucci, L., De Simone, F., Immune protection against foot-and-mouth disease virus studied using virus-neutralizing and non-neutralizing concentrations of monoclonal antibodies. Immunology 58:3 (1986), 421–428.
    • (1986) Immunology , vol.58 , Issue.3 , pp. 421-428
    • McCullough, K.C.1    Crowther, J.R.2    Butcher, R.N.3    Carpenter, W.C.4    Brocchi, E.5    Capucci, L.6    De Simone, F.7
  • 43
    • 0020029316 scopus 로고
    • Opsonic activity of human immune serum on in vitro phagocytosis of Plasmodium falciparum infected red blood cells by monocytes
    • [43] Celada, A., Cruchaud, A., Perrin, L.H., Opsonic activity of human immune serum on in vitro phagocytosis of Plasmodium falciparum infected red blood cells by monocytes. Clin. Exp. Immunol. 47:3 (1982), 635–644.
    • (1982) Clin. Exp. Immunol. , vol.47 , Issue.3 , pp. 635-644
    • Celada, A.1    Cruchaud, A.2    Perrin, L.H.3
  • 44
    • 0017755887 scopus 로고
    • Differences in the mode of phagocytosis with Fc and C3 receptors in macrophages
    • [44] Kaplan, G., Differences in the mode of phagocytosis with Fc and C3 receptors in macrophages. Scand. J. Immunol. 6:8 (1977), 797–807.
    • (1977) Scand. J. Immunol. , vol.6 , Issue.8 , pp. 797-807
    • Kaplan, G.1
  • 45
    • 0029829896 scopus 로고    scopus 로고
    • Molecular definition of distinct cytoskeletal structures involved in complement- and Fc receptor-mediated phagocytosis in macrophages
    • [45] Allen, L.A., Aderem, A., Molecular definition of distinct cytoskeletal structures involved in complement- and Fc receptor-mediated phagocytosis in macrophages. J. Exp. Med. 184:2 (1996), 627–637.
    • (1996) J. Exp. Med. , vol.184 , Issue.2 , pp. 627-637
    • Allen, L.A.1    Aderem, A.2
  • 46
    • 0032573378 scopus 로고    scopus 로고
    • Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
    • [46] Caron, E., Hall, A., Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 282:5394 (1998), 1717–1721.
    • (1998) Science , vol.282 , Issue.5394 , pp. 1717-1721
    • Caron, E.1    Hall, A.2
  • 47
    • 0036065586 scopus 로고    scopus 로고
    • CR3 (CD11b/CD18) and CR4 (CD11c/CD18) are involved in complement-independent antibody-mediated phagocytosis of Cryptococcus neoformans
    • [47] Taborda, C.P., Casadevall, A., CR3 (CD11b/CD18) and CR4 (CD11c/CD18) are involved in complement-independent antibody-mediated phagocytosis of Cryptococcus neoformans. Immunity 16:6 (2002), 791–802.
    • (2002) Immunity , vol.16 , Issue.6 , pp. 791-802
    • Taborda, C.P.1    Casadevall, A.2
  • 48
    • 0037103252 scopus 로고    scopus 로고
    • Complement receptor 3 (CD11b/CD18) mediates type I and type II phagocytosis during nonopsonic and opsonic phagocytosis, respectively
    • [48] Le Cabec, V., Carreno, S., Moisand, A., Bordier, C., Maridonneau-Parini, I., Complement receptor 3 (CD11b/CD18) mediates type I and type II phagocytosis during nonopsonic and opsonic phagocytosis, respectively. J. Immunol. 169:4 (2002), 2003–2009.
    • (2002) J. Immunol. , vol.169 , Issue.4 , pp. 2003-2009
    • Le Cabec, V.1    Carreno, S.2    Moisand, A.3    Bordier, C.4    Maridonneau-Parini, I.5
  • 49
    • 0023111156 scopus 로고
    • Modulation of FcR function by complement: subcomponent C1q enhances the phagocytosis of IgG-opsonized targets by human monocytes and culture-derived macrophages
    • [49] Bobak, D.A., Gaither, T.A., Frank, M.M., Tenner, A.J., Modulation of FcR function by complement: subcomponent C1q enhances the phagocytosis of IgG-opsonized targets by human monocytes and culture-derived macrophages. J. Immunol. 138:4 (1987), 1150–1156.
    • (1987) J. Immunol. , vol.138 , Issue.4 , pp. 1150-1156
    • Bobak, D.A.1    Gaither, T.A.2    Frank, M.M.3    Tenner, A.J.4
  • 50
    • 84918516932 scopus 로고    scopus 로고
    • Phagocytosis: Enhancement, in eLS
    • John Wiley & Sons, Ltd
    • [50] Peiser, Leanne, Gordon, Siamon, Phagocytosis: Enhancement, in eLS. 2001, John Wiley & Sons, Ltd.
    • (2001)
    • Peiser, L.1    Gordon, S.2
  • 51
    • 84920724791 scopus 로고    scopus 로고
    • Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment
    • [51] Lavin, Y., Winter, D., Blecher-Gonen, R., David, E., Keren-Shaul, H., Merad, M., Jung, S., Amit, I., Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell 159:6 (2014), 1312–1326.
    • (2014) Cell , vol.159 , Issue.6 , pp. 1312-1326
    • Lavin, Y.1    Winter, D.2    Blecher-Gonen, R.3    David, E.4    Keren-Shaul, H.5    Merad, M.6    Jung, S.7    Amit, I.8
  • 53
    • 84927613295 scopus 로고    scopus 로고
    • Macrophages: development and tissue specialization
    • [53] Varol, C., Mildner, A., Jung, S., Macrophages: development and tissue specialization. Annu. Rev. Immunol. 33 (2015), 643–675.
    • (2015) Annu. Rev. Immunol. , vol.33 , pp. 643-675
    • Varol, C.1    Mildner, A.2    Jung, S.3
  • 55
    • 84897556094 scopus 로고    scopus 로고
    • The M1 and M2 paradigm of macrophage activation: time for reassessment
    • [55] Martinez, F.O., Gordon, S., The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep., 6, 2014, 13.
    • (2014) F1000Prime Rep. , vol.6 , pp. 13
    • Martinez, F.O.1    Gordon, S.2
  • 56
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
    • [56] Biswas, S.K., Mantovani, A., Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat. Immunol. 11:10 (2010), 889–896.
    • (2010) Nat. Immunol. , vol.11 , Issue.10 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 57
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • [57] Sica, A., Mantovani, A., Macrophage plasticity and polarization: in vivo veritas. J. Clin. Invest. 122:3 (2012), 787–795.
    • (2012) J. Clin. Invest. , vol.122 , Issue.3 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 58
    • 84870821865 scopus 로고    scopus 로고
    • Haemophilus ducreyi-induced interleukin-10 promotes a mixed M1 and M2 activation program in human macrophages
    • [58] Li, W., Katz, B.P., Spinola, S.M., Haemophilus ducreyi-induced interleukin-10 promotes a mixed M1 and M2 activation program in human macrophages. Infect. Immun. 80:12 (2012), 4426–4434.
    • (2012) Infect. Immun. , vol.80 , Issue.12 , pp. 4426-4434
    • Li, W.1    Katz, B.P.2    Spinola, S.M.3
  • 60
    • 75649097879 scopus 로고    scopus 로고
    • Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion
    • [60] Varin, A., Mukhopadhyay, S., Herbein, G., Gordon, S., Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion. Blood 115:2 (2010), 353–362.
    • (2010) Blood , vol.115 , Issue.2 , pp. 353-362
    • Varin, A.1    Mukhopadhyay, S.2    Herbein, G.3    Gordon, S.4
  • 61
    • 20644450804 scopus 로고    scopus 로고
    • Negative regulation of toll-like receptor-mediated immune responses
    • [61] Liew, F.Y., Xu, D., Brint, E.K., O'Neill, L.A., Negative regulation of toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 5:6 (2005), 446–458.
    • (2005) Nat. Rev. Immunol. , vol.5 , Issue.6 , pp. 446-458
    • Liew, F.Y.1    Xu, D.2    Brint, E.K.3    O'Neill, L.A.4
  • 62
    • 70349559403 scopus 로고    scopus 로고
    • Endotoxin tolerance: new mechanisms, molecules and clinical significance
    • [62] Biswas, S.K., Lopez-Collazo, E., Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol. 30:10 (2009), 475–487.
    • (2009) Trends Immunol. , vol.30 , Issue.10 , pp. 475-487
    • Biswas, S.K.1    Lopez-Collazo, E.2
  • 63
    • 84954425610 scopus 로고    scopus 로고
    • The regulation of endotoxin tolerance and its impact on macrophage activation
    • [63] Collins, P.E., Carmody, R.J., The regulation of endotoxin tolerance and its impact on macrophage activation. Crit. Rev. Immunol. 35:4 (2015), 293–323.
    • (2015) Crit. Rev. Immunol. , vol.35 , Issue.4 , pp. 293-323
    • Collins, P.E.1    Carmody, R.J.2
  • 64
    • 34250823515 scopus 로고    scopus 로고
    • Gene-specific control of inflammation by TLR-induced chromatin modifications
    • [64] Foster, S.L., Hargreaves, D.C., Medzhitov, R., Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 447:7147 (2007), 972–978.
    • (2007) Nature , vol.447 , Issue.7147 , pp. 972-978
    • Foster, S.L.1    Hargreaves, D.C.2    Medzhitov, R.3
  • 66
    • 79959558906 scopus 로고    scopus 로고
    • Endotoxin tolerance represents a distinctive state of alternative polarization (M2) in human mononuclear cells
    • [66] Pena, O.M., Pistolic, J., Raj, D., Fjell, C.D., Hancock, R.E., Endotoxin tolerance represents a distinctive state of alternative polarization (M2) in human mononuclear cells. J. Immunol. 186:12 (2011), 7243–7254.
    • (2011) J. Immunol. , vol.186 , Issue.12 , pp. 7243-7254
    • Pena, O.M.1    Pistolic, J.2    Raj, D.3    Fjell, C.D.4    Hancock, R.E.5


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