-
1
-
-
0027975453
-
Nitric oxide: A physiologic messenger molecule
-
Bredt D.S., Snyder S.H. Nitric oxide: a physiologic messenger molecule. Annu. Rev. Biochem. 63:1994;175-195.
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 175-195
-
-
Bredt, D.S.1
Snyder, S.H.2
-
2
-
-
0344352487
-
Protective effect of N-(3-(aminomethyl) benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation
-
Cárdenas A., De Alba J., Moro M.A., Leza J.C., Lorenzo P., Lizasoain I. Protective effect of N-(3-(aminomethyl) benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation. Eur. J. Pharmacol. 354:1998;161-165.
-
(1998)
Eur. J. Pharmacol.
, vol.354
, pp. 161-165
-
-
Cárdenas, A.1
De Alba, J.2
Moro, M.A.3
Leza, J.C.4
Lorenzo, P.5
Lizasoain, I.6
-
3
-
-
0345120955
-
Use of brain slices in the study of pathogenic role of inducible nitric oxide synthase in cerebral ischemia-reperfusion
-
De Alba J., Cardenas A., Moro M.A., Leza J.C., Lorenzo P., Lizasoain I. Use of brain slices in the study of pathogenic role of inducible nitric oxide synthase in cerebral ischemia-reperfusion. Gen. Pharmacol. 32:1999;577-581.
-
(1999)
Gen. Pharmacol.
, vol.32
, pp. 577-581
-
-
De Alba, J.1
Cardenas, A.2
Moro, M.A.3
Leza, J.C.4
Lorenzo, P.5
Lizasoain, I.6
-
4
-
-
0030582831
-
Ebselen and cytokine-induced nitric oxide synthase expression in insulin-producing cells
-
de-Mello M.A.R., Flodström M., Eizirik D.L. Ebselen and cytokine-induced nitric oxide synthase expression in insulin-producing cells. Biochem. Pharmacol. 52:1996;1703-1709.
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 1703-1709
-
-
De-Mello, M.A.R.1
Flodström, M.2
Eizirik, D.L.3
-
5
-
-
0028922422
-
Nitric oxide: Pathophysiological mechanisms
-
Gross S.S., Wolin M.S. Nitric oxide: pathophysiological mechanisms. Annu. Rev. Physiol. 57:1995;737-769.
-
(1995)
Annu. Rev. Physiol.
, vol.57
, pp. 737-769
-
-
Gross, S.S.1
Wolin, M.S.2
-
6
-
-
0028240615
-
Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global oxygen and glucose deprivation
-
Endoh M., Maiese K., Wagner J. Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global oxygen and glucose deprivation. Brain Res. 651:1994;92-100.
-
(1994)
Brain Res.
, vol.651
, pp. 92-100
-
-
Endoh, M.1
Maiese, K.2
Wagner, J.3
-
7
-
-
0035783981
-
Ischemia: Astrocytes show their sensitive side
-
Fern R. Ischemia: astrocytes show their sensitive side. Prog. Brain Res. 132:2001;405-411.
-
(2001)
Prog. Brain Res.
, vol.132
, pp. 405-411
-
-
Fern, R.1
-
8
-
-
0034815912
-
The neuroprotective effect agent ebselen modifies NMDA receptor function via the redox modulatory site
-
Herin G.A., Du S., Aizenman E. The neuroprotective effect agent ebselen modifies NMDA receptor function via the redox modulatory site. J. Neurochem. 78:2001;1307-1314.
-
(2001)
J. Neurochem.
, vol.78
, pp. 1307-1314
-
-
Herin, G.A.1
Du, S.2
Aizenman, E.3
-
9
-
-
0028891572
-
Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage
-
Iadecola C., Zhang F.Y., Xu X. Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am. J. Physiol. 268:1995;R286-R292.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Iadecola, C.1
Zhang, F.Y.2
Xu, X.3
-
10
-
-
84984591164
-
Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice
-
Jacques-Silva M.C., Nogueira C.W., Broch L.C., Flores E.M., Rocha J.B.T. Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice. Pharmacol. Toxicol. 88:2001;119-125.
-
(2001)
Pharmacol. Toxicol.
, vol.88
, pp. 119-125
-
-
Jacques-Silva, M.C.1
Nogueira, C.W.2
Broch, L.C.3
Flores, E.M.4
Rocha, J.B.T.5
-
11
-
-
0033485704
-
Clinical trials with neuroprotective drugs in acute ischaemic stroke: Are we doing the right thing?
-
Keyser J., Sulter G., Luiten P.G. Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing? Trends Neurosci. 22:1999;535-540.
-
(1999)
Trends Neurosci.
, vol.22
, pp. 535-540
-
-
Keyser, J.1
Sulter, G.2
Luiten, P.G.3
-
12
-
-
18244415707
-
Defenses against peroxynitrite: Selenocompounds and flavonoids
-
Klotz L.O., Sies H. Defenses against peroxynitrite: selenocompounds and flavonoids. Toxicol. Lett. 14-141:2003;125-132.
-
(2003)
Toxicol. Lett.
, vol.141
, Issue.14
, pp. 125-132
-
-
Klotz, L.O.1
Sies, H.2
-
13
-
-
0033600277
-
The changing landscape of ischaemic brain injury mechanisms
-
Lee J.-M., Zipfel G.J., Choi D.W. The changing landscape of ischaemic brain injury mechanisms. Nature. 399:1999;A7-A14.
-
(1999)
Nature
, vol.399
-
-
Lee, J.-M.1
Zipfel, G.J.2
Choi, D.W.3
-
14
-
-
0032845121
-
Ischemic cell death in brain neurons
-
Lipton P. Ischemic cell death in brain neurons. Physiol. Rev. 79:1999;1431-1568.
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1431-1568
-
-
Lipton, P.1
-
15
-
-
84984587031
-
Comparative deposition of diphenyl diselenide in liver, kidney, and brain of mice
-
Maciel E.N., Flores E.M., Rocha J.B.T., Folmer V. Comparative deposition of diphenyl diselenide in liver, kidney, and brain of mice. Bull. Environ. Contam. Toxicol. 70:2003;470-476.
-
(2003)
Bull. Environ. Contam. Toxicol.
, vol.70
, pp. 470-476
-
-
Maciel, E.N.1
Flores, E.M.2
Rocha, J.B.T.3
Folmer, V.4
-
16
-
-
0035385139
-
Chemistry of biologically important synthetic organoselenium compounds
-
Mugesh G., du Mont W.-W., Sies H. Chemistry of biologically important synthetic organoselenium compounds. Chem. Rev. 101:2001;2125-2179.
-
(2001)
Chem. Rev.
, vol.101
, pp. 2125-2179
-
-
Mugesh, G.1
Du Mont, W.-W.2
Sies, H.3
-
17
-
-
0021185122
-
A novel biologically active seleno-organic compound. I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen)
-
Müller A., Cadenas E., Graf P., Sies H. A novel biologically active seleno-organic compound. I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen). Biochem. Pharmacol. 33:1984;3235-3239.
-
(1984)
Biochem. Pharmacol.
, vol.33
, pp. 3235-3239
-
-
Müller, A.1
Cadenas, E.2
Graf, P.3
Sies, H.4
-
18
-
-
84984585825
-
Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo
-
Nogueira C.W., Rotta L.N., Perry M.L., Souza D.O., Rocha J.B.T. Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo. Brain Res. 906:2001;157-163.
-
(2001)
Brain Res.
, vol.906
, pp. 157-163
-
-
Nogueira, C.W.1
Rotta, L.N.2
Perry, M.L.3
Souza, D.O.4
Rocha, J.B.T.5
-
19
-
-
84984578367
-
Investigations into the potential neurotoxicity induced by diselenides in mice and rats
-
Nogueira C.W., Meotti F.C., Curte E., Pilissao C., Zeni G., Rocha J.B.T. Investigations into the potential neurotoxicity induced by diselenides in mice and rats. Toxicology. 183:2003;29-37.
-
(2003)
Toxicology
, vol.183
, pp. 29-37
-
-
Nogueira, C.W.1
Meotti, F.C.2
Curte, E.3
Pilissao, C.4
Zeni, G.5
Rocha, J.B.T.6
-
20
-
-
84984572868
-
Anti-inflammatory and antinociceptive activity of diphenyl diselenide
-
Nogueira C.W., Quinhones E.B., Jung E.A., Zeni G., Rocha J.B.T. Anti-inflammatory and antinociceptive activity of diphenyl diselenide. Inflamm. Res. 52:2003;56-63.
-
(2003)
Inflamm. Res.
, vol.52
, pp. 56-63
-
-
Nogueira, C.W.1
Quinhones, E.B.2
Jung, E.A.3
Zeni, G.4
Rocha, J.B.T.5
-
21
-
-
84983725597
-
Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons
-
Porciúncula L.O., Rocha J.B.T., Boeck C.R., Vendite D., O Souza D. Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons. Neurosci. Lett. 299:2001;217-220.
-
(2001)
Neurosci. Lett.
, vol.299
, pp. 217-220
-
-
Porciúncula, L.O.1
Rocha, J.B.T.2
Boeck, C.R.3
Vendite, D.4
O Souza, D.5
-
22
-
-
84984565443
-
Neuroprotective effect of ebselen on rat hippocampal slices submitted to oxygen-glucose deprivation: Correlation with immunocontent of inducible nitric oxide synthase
-
Porciúncula L.O., Cimarosti H., Rocha J.B.T., Vinadé L., Ghisleni G., Salbego C.G., Souza D.O. Neuroprotective effect of ebselen on rat hippocampal slices submitted to oxygen-glucose deprivation: correlation with immunocontent of inducible nitric oxide synthase. Neurosci. Lett. 346:2003;101-104.
-
(2003)
Neurosci. Lett.
, vol.346
, pp. 101-104
-
-
Porciúncula, L.O.1
Cimarosti, H.2
Rocha, J.B.T.3
Vinadé, L.4
Ghisleni, G.5
Salbego, C.G.6
Souza, D.O.7
-
23
-
-
0034662094
-
The importance of selenium to human health
-
Rayman M.P. The importance of selenium to human health. Lancet. 356:2000;233-241.
-
(2000)
Lancet
, vol.356
, pp. 233-241
-
-
Rayman, M.P.1
-
24
-
-
84984578569
-
Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain
-
Rossato J.I., Ketzer L.A., Centurião F.B., Silva S.J., Ludtke D.S., Zeni G., Braga A.L., Rubin M.A., Rocha J.B. Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain. Neurochem. Res. 27:2002;297-303.
-
(2002)
Neurochem. Res.
, vol.27
, pp. 297-303
-
-
Rossato, J.I.1
Ketzer, L.A.2
Centurião, F.B.3
Silva, S.J.4
Ludtke, D.S.5
Zeni, G.6
Braga, A.L.7
Rubin, M.A.8
Rocha, J.B.9
-
25
-
-
84984569420
-
Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alteration produced by intra-striatal quinolinic acid administration in the rat
-
Rossato J.I., Zeni G., Mello C.F., Rubin M.A., Rocha J.B.T. Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alteration produced by intra-striatal quinolinic acid administration in the rat. Neurosci. Lett. 318:2002;137-140.
-
(2002)
Neurosci. Lett.
, vol.318
, pp. 137-140
-
-
Rossato, J.I.1
Zeni, G.2
Mello, C.F.3
Rubin, M.A.4
Rocha, J.B.T.5
-
26
-
-
0029114721
-
Molecular actions of ebselen - An anti-inflammatory antioxidant
-
Schewe T. Molecular actions of ebselen - an anti-inflammatory antioxidant. Gen. Pharmacol. 26:1995;1153-1169.
-
(1995)
Gen. Pharmacol.
, vol.26
, pp. 1153-1169
-
-
Schewe, T.1
-
27
-
-
0033866907
-
Selenoorganic compound, ebselen, inhibits nitric oxide and tumor necrosis factor-α production by the modulation of jun-N-terminal kinase and the NF-κB signaling pathway in rat kupffer cells
-
Shimohashi N., Nakamuta M., Uchimura K., Sugimoto R., Iwamoto H., Enjoji M., Nawata H. Selenoorganic compound, ebselen, inhibits nitric oxide and tumor necrosis factor-α production by the modulation of jun-N-terminal kinase and the NF-κB signaling pathway in rat kupffer cells. J. Cell Biochem. 78:2000;595-606.
-
(2000)
J. Cell Biochem.
, vol.78
, pp. 595-606
-
-
Shimohashi, N.1
Nakamuta, M.2
Uchimura, K.3
Sugimoto, R.4
Iwamoto, H.5
Enjoji, M.6
Nawata, H.7
-
28
-
-
0031963836
-
Ebselen in acute ischemic stroke: A placebo-controlled, double-bind clinical trial
-
Yamaguchi T., Sano K., Takakura K., Saito I., Shinohara Y., Asano T., Yasuhara H. Ebselen in acute ischemic stroke: a placebo-controlled, double-bind clinical trial. Stroke. 29:1998;12-17.
-
(1998)
Stroke
, vol.29
, pp. 12-17
-
-
Yamaguchi, T.1
Sano, K.2
Takakura, K.3
Saito, I.4
Shinohara, Y.5
Asano, T.6
Yasuhara, H.7
-
29
-
-
0037131424
-
A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase
-
Zhao R., Holmgren A. A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase. J. Biol. Chem. 277:2002;39456-39462.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39456-39462
-
-
Zhao, R.1
Holmgren, A.2
-
30
-
-
0037172997
-
Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant
-
Zhao R., Masayasu H., Holmgren A. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proc. Natl. Acad. Sci. USA. 99:2002;8579-8584.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8579-8584
-
-
Zhao, R.1
Masayasu, H.2
Holmgren, A.3
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