Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles-part 2: Mass spectrometric methods

mAbs

Volumn 7, Issue 4, 2015, Pages 732-742

  Reusch, Dietmar ^a   Haberger, Markus ^a   Falck, David ^b   Peter, Britta ^a   Maier, Bernd ^a   Gassner, Jana ^a   Hook, Michaela ^a   Wagner, Katharina ^a   Bonnington, Lea ^a   Bulau, Patrick ^a   Wuhrer, Manfred ^b,c  

^a ROCHE DIAGNOSTICS GMBH   (Germany)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

ESI MS; Glycan analysis; HILIC UPLC; IgG glycosylation; LC MS; MALDI MS; Mass spectrometry; Method comparison; Monoclonal antibody (mAb)

Indexed keywords

IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; SIALIC ACID DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; GLYCOSYLATION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; ANIMAL; CHEMISTRY; CHO CELL LINE; COMPARATIVE STUDY; CRICETULUS; HAMSTER; HUMAN;

ANIMALS; ANTIBODIES, MONOCLONAL; CHO CELLS; CRICETINAE; CRICETULUS; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; RECOMBINANT PROTEINS; SIALIC ACIDS;

EID: 84983656017     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.1080/19420862.2015.1045173     Document Type: Article

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