Characterization of evolving biomechanical properties of tissue engineered vascular grafts in the arterial circulation

Journal of Biomechanics

Volumn 47, Issue 9, 2014, Pages 2070-2079

  Udelsman, Brooks V ^a   Khosravi, Ramak ^a   Miller, Kristin S ^b   Dean, Ethan W ^a   Bersi, Matthew R ^b   Rocco, Kevin ^b   Yi, Tai ^c   Humphrey, Jay D ^b   Breuer, Christopher K ^c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Yale University   (United States)

^c NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

Growth and remodeling; Mechanical homeostasis; Neovascularization; Tissue engineering

Indexed keywords

BIOMECHANICS; COLLAGEN; ELASTIN; GLYCOPROTEINS; MECHANICAL TESTING; STIFFNESS; TISSUE; TISSUE ENGINEERING;

BIAXIAL MECHANICAL TESTING; BIOMECHANICAL PROPERTIES; COLLAGEN DEPOSITION; GROWTH AND REMODELING; INDIVIDUAL COMPONENTS; MECHANICAL HOMEOSTASIS; NEO-VASCULARIZATION; TISSUE ENGINEERED VASCULAR GRAFTS;

SCAFFOLDS (BIOLOGY);

COLLAGEN; COLLAGENASE; ELASTASE; ELASTIN; POLYCAPROLACTONE; POLYLACTIC ACID; POLYMER; TISSUE SCAFFOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTERIAL CIRCULATION; ARTICLE; BIOMECHANICS; BLOOD VESSEL GRAFT; BONE MARROW CELL; CONTROLLED STUDY; DEGRADATION; FEMALE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MATHEMATICAL MODEL; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RIGIDITY; SMOOTH MUSCLE FIBER; TISSUE ENGINEERING; ULTRASOUND;

GROWTH AND REMODELING; MECHANICAL HOMEOSTASIS; NEOVASCULARIZATION; TISSUE ENGINEERING;

ANIMALS; AORTA; BLOOD VESSEL PROSTHESIS; COLLAGEN; ELASTIN; FEMALE; LACTIC ACID; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, SMOOTH MUSCLE; POLYESTERS; POLYMERS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84901482297     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2014.03.011     Document Type: Article

References (20)

1. Baek S., Rajagopal K.R., Humphrey J.D. A theoretical model of enlarging intracranial fusiform aneurysms. J. Biomech. Eng. 2006, 128:142-149.
2. Collins M.J., Eberth J.F., Wilson E., Humphrey J.D. Acute mechanical effects of elastase on the infrarenal mouse aorta: implications for models of aneurysms. J. Biomech. 2012, 45:660-665.
3. Ferruzzi J., Bersi M.R., Humphrey J.D. Biomechanical phenotyping of central arteries in health and disease: advantages of and methods for murine models. Ann. Biomed. Eng. 2013, 41:1311-1330.
4. Ferruzzi J., Collins M.J., Yeh A.T., Humphrey J.D. Mechanical assessment of elastin integrity in fibrillin-1-deficient carotid arteries: implications for Marfan syndrome. Cardiovasc. Res. 2011, 92:287-295.
5. Gleason R.L., Gray S.P., Wilson E., Humphrey J.D. A multiaxial computer-controlled organ culture and biomechanical device for mouse carotid arteries. J. Biomech. Eng. 2004, 126:787-795.
6. Gleason R.L., Humphrey J.D. Effects of a sustained extension on arterial growth and remodeling: a theoretical study. J. Biomech. 2005, 38:1255-1261.
7. Greve J.M., Les A.S., Tang B.T., Draney Blomme M.T., Wilson N.M., Dalman R.L., Pelc N.J., Taylor C.A. Allometric scaling of wall shear stress from mice to humans: quantification using cine phase-contrast MRI and computational fluid dynamics. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H1700-H1708.
8. Humphrey J.D. Vascular adaptation and mechanical homeostasis at tissue, cellular, and sub-cellular levels. Cell Biochem. Biophys. 2008, 50:53-78.
9. Humphrey J.D., Eberth J.F., Dye W.W., Gleason R.L. Fundamental role of axial stress in compensatory adaptations by arteries. J. Biomech. 2009, 42:1-8.
10. Kassam, A.B., Horowitz, M., Chang, Y.F., Peters, D., 2004. Altered arterial homeostasis and cerebral aneurysms: a molecular epidemiology study. Neurosurgery 54, 1450-1460; discussion 1460-1462.
11. Miller, K.S., Lee, Y.U., Naito, Y., Breuer, C.K., Humphrey, J.D., 2013. Computational model of the in vivo development of a tissue engineered vein from an implanted polymeric construct. J. Biomech. e-pub ahead of print. http://dx.doi.org/10.1016/j.jbiomech.2013.10.009i.
12. Mirensky, T.L., Nelson, G.N., Brennan, M.P., Roh, J.D., Hibino, N., Yi, T., Shinoka, T., Breuer, C.K., 2009. Tissue-engineered arterial grafts: long-term results after implantation in a small animal model. J. Pediatr. Surg. 44, 1127-1132; discussion 1132-1133.
13. Naito Y., Lee Y.U., Yi T., Church S.N., Solomon D., Humphrey J.D., Shinoka T., Breuer C.K. Beyond burst pressure: initial evaluation of the natural history of the biaxial mechanical properties of tissue engineered vascular grafts in the venous circulation using a murine model. Tissue Eng. Part A 2013.
14. Naito Y., Williams-Fritze M., Duncan D.R., Church S.N., Hibino N., Madri J.A., Humphrey J.D., Shinoka T., Breuer C.K. Characterization of the natural history of extracellular matrix production in tissue-engineered vascular grafts during neovessel formation. Cells Tissues Organs 2012, 195:60-72.
15. Niklason L.E., Yeh A.T., Calle E.A., Bai Y., Valentin A., Humphrey J.D. Enabling tools for engineering collagenous tissues integrating bioreactors, intravital imaging, and biomechanical modeling. Proc. Natl. Acad. Sci. USA 2010, 107:3335-3339.
16. Peters D.G., Kassam A.B., Feingold E., Heidrich-O'Hare E., Yonas H., Ferrell R.E., Brufsky A. Molecular anatomy of an intracranial aneurysm: coordinated expression of genes involved in wound healing and tissue remodeling. Stroke 2001, 32:1036-1042.
17. Roh J.D., Nelson G.N., Brennan M.P., Mirensky T.L., Yi T., Hazlett T.F., Tellides G., Sinusas A.J., Pober J.S., Saltzman W.M., Kyriakides T.R., Breuer C.K. Small-diameter biodegradable scaffolds for functional vascular tissue engineering in the mouse model. Biomaterials 2008, 29:1454-1463.
18. Roh J.D., Sawh-Martinez R., Brennan M.P., Jay S.M., Devine L., Rao D.A., Yi T., Mirensky T.L., Nalbandian A., Udelsman B., Hibino N., Shinoka T., Saltzman W.M., Snyder E., Kyriakides T.R., Pober J.S., Breuer C.K. Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. Proc. Natl. Acad. Sci. USA 2010, 107:4669-4674.
19. Wagenseil J.E., Mecham R.P. Vascular extracellular matrix and arterial mechanics. Physiol. Rev. 2009, 89:957-989.
20. Wu W., Allen R.A., Wang Y. Fast-degrading elastomer enables rapid remodeling of a cell-free synthetic graft into a neoartery. Nat. Med. 2012, 18:1148-1153.