Computational modelling suggests good, bad and ugly roles of glycosaminoglycans in arterial wall mechanics and mechanobiology

Journal of the Royal Society Interface

Volumn 11, Issue 97, 2014, Pages

  Roccabianca, S ^a   Bellini, C ^a   Humphrey, J D ^a,b  

^a Yale University   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anoikis; Hyaluronan; Mechanosensing; Stress analysis; Versican

Indexed keywords

COMPUTER SIMULATION; FINITE ELEMENT METHOD; HYALURONIC ACID; STRESS ANALYSIS;

ANOIKIS; ARTERIAL PATHOLOGIES; ARTERIAL WALL MECHANICS; COMPUTATIONAL MODELLING; COMPUTATIONAL SIMULATION; HYALURONAN; MECHANOSENSING; VERSICAN;

AGGREGATES;

GLYCOSAMINOGLYCAN; HYALURONIC ACID; VERSICAN; PROTEOGLYCAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY WALL; ARTICLE; BLOOD VESSEL WALL; CARBOHYDRATE ANALYSIS; COMMON CAROTID ARTERY; ELASTIC FIBER; KINEMATICS; MOUSE; NONHUMAN; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WALL STRESS; ANIMAL; BIOLOGICAL MODEL; CAROTID ARTERY DISEASE; COMPUTER SIMULATION; INTIMA; MECHANICAL STRESS; MECHANOTRANSDUCTION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SHEAR STRENGTH; TENSILE STRENGTH;

ANIMALS; CAROTID ARTERY DISEASES; CAROTID ARTERY, COMMON; COMPUTER SIMULATION; GLYCOSAMINOGLYCANS; MECHANOTRANSDUCTION, CELLULAR; MICE; MODELS, CARDIOVASCULAR; PROTEOGLYCANS; SHEAR STRENGTH; STRESS, MECHANICAL; TENSILE STRENGTH; TUNICA INTIMA;

EID: 84903639588     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.0397     Document Type: Article

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