Inhibition of Bacillus anthracis metallo-β-lactamase by compounds with hydroxamic acid functionality

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 31, Issue , 2016, Pages 132-137

  Kim, Sung Kun ^a   Demuth, Mara ^a   Schlesinger, Sara R ^b   Kim, Sung Joon ^b   Urbanczyk, Jonathan ^c   Shaw, Robert W ^d   Shin, Hyunshun ^c  

^a NORTHEASTERN STATE UNIVERSITY   (United States)

^b BAYLOR UNIVERSITY   (United States)

^c MCMURRY UNIVERSITY   (United States)

^d TEXAS TECH UNIVERSITY   (United States)

Author keywords

Enzyme kinetics; inhibition; lactamase

Indexed keywords

3 (HEPTYLOXY) N HYDROXYBENZAMIDE; BACTERIAL PROTEIN; BETA LACTAMASE INHIBITOR; BLA2 PROTEIN; HYDROXAMIC ACID DERIVATIVE; METALLO BETA LACTAMASE; METHYL 3 [(6 METHOXY 6 OXOHEXYL)OXY]BENZOATE; N HYDROXY 3 [[6 (HYDROXYAMINO) 6 OXOHEXYL]OXY]BENZAMIDE; UNCLASSIFIED DRUG; ZINC ION; BETA LACTAMASE; HYDROXAMIC ACID;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS ANTHRACIS; BINDING AFFINITY; CLINICAL EFFECTIVENESS; COMPETITIVE INHIBITION; COMPUTER MODEL; CONCENTRATION RESPONSE; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; GROWTH INHIBITION; NONHUMAN; PRIORITY JOURNAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ENZYMOLOGY; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BACILLUS ANTHRACIS; BETA-LACTAMASE INHIBITORS; BETA-LACTAMASES; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROXAMIC ACIDS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84983516169     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756366.2016.1222580     Document Type: Article

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