Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas

Nature Genetics

Volumn 48, Issue 10, 2016, Pages 1253-1259

  Clark, Victoria E ^a   Harmancl, Akdes Serin ^a   Bai, Hanwen ^a   Youngblood, Mark W ^a   Lee, Tong Ihn ^b   Baranoski, Jacob F ^a   Ercan Sencicek, A Gulhan ^a   Abraham, Brian J ^b   Weintraub, Abraham S ^b   Hnisz, Denes ^b   Simon, Matthias ^c   Krischek, Boris ^d   Erson Omay, E Zeynep ^a   Henegariu, Octavian ^a   Carrión Grant, Geneive ^a   Mishra Gorur, Ketu ^a   Durán, Daniel ^a   Goldmann, Johanna E ^b   Schramm, Johannes ^e   Goldbrunner, Roland ^d   Piepmeier, Joseph M ^a   Vortmeyer, Alexander O ^a   Günel, Jennifer Moliterno ^a   Bilgüvar, Kaya ^a   Yasuno, Katsuhito ^a   Young, Richard A ^b,f   Günel, Murat ^a,g   more..

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF BONN   (Germany)

^d UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^e UNIVERSITY OF BONN   (Germany)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g YALE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KRUPPEL LIKE FACTOR 4; RNA POLYMERASE II; WNT6 PROTEIN; KRUPPEL LIKE FACTOR; MERLIN; TRAF7 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR;

ARTICLE; CARCINOGENESIS; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; COPY NUMBER VARIATION; GENE; GENE DELETION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; MENINGIOMA; MISSENSE MUTATION; NEUROPATHOLOGY; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; POLR2A GENE; PRIORITY JOURNAL; SOMATIC MUTATION; STEM CELL; CHROMOSOME 22; CLASSIFICATION; COHORT ANALYSIS; DNA MUTATIONAL ANALYSIS; ENHANCER REGION; ENZYME ACTIVE SITE; EXOME; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; MUTATION;

CATALYTIC DOMAIN; CHROMOSOMES, HUMAN, PAIR 22; COHORT STUDIES; DNA MUTATIONAL ANALYSIS; ENHANCER ELEMENTS, GENETIC; EXOME; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOTYPE; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MENINGEAL NEOPLASMS; MENINGIOMA; MUTATION; NEUROFIBROMIN 2; RNA POLYMERASE II; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

EID: 84983479137     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3651     Document Type: Article

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