Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells

BMC Cancer

Volumn 16, Issue 1, 2016, Pages

  Chen, Ming Feng ^a,b   Huang, S Joseph ^c,d   Huang, Chao Cheng ^e,f   Liu, Pei Shan ^g   Lin, Kun I ^h   Liu, Ching Wen ⁱ   Hsieh, Wen Chuan ^c   Shiu, Li Yen ^a,j   Chen, Chang Han ^f,i,k  

^a E DA HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c I SHOU UNIVERSITY   (Taiwan)

^d UNIVERSITY OF SOUTH FLORIDA   (United States)

^e CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^f CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^g SOOCHOW UNIVERSITY   (Taiwan)

^h CHANG BING SHOW CHWAN MEMORIAL HOSPITAL   (Taiwan)

ⁱ KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^j E DA Cancer Hospital   (Taiwan)

^k NATIONAL CHI NAN UNIVERSITY   (Taiwan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ADENOSINE TRIPHOSPHATE; ALPHA SMOOTH MUSCLE ACTIN; CASPASE 3; CASPASE 9; COLLAGEN TYPE 1; COLLAGEN TYPE 3; SAIKOSAPONIN D; ANTINEOPLASTIC AGENT; BENZOYLCARBONYL-ASPARTYL-GLUTAMYL-VALYL-ASPARTYL-FLUOROMETHYL KETONE; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, RAT; CASP9 PROTEIN, HUMAN; CASP9 PROTEIN, RAT; CASPASE INHIBITOR; HERBACEOUS AGENT; OLEANOLIC ACID; OLIGOPEPTIDE; SAIKOSAPONIN; SAPONIN; TRITERPENE;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL FUNCTION; CELL POPULATION; CELL STRUCTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MAMMAL CELL; MITOCHONDRION; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; STELLATE CELL; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; CELL LINE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; HEPATIC STELLATE CELL; LIVER CIRRHOSIS; METABOLISM; RADIX BUPLEURI; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BUPLEURUM; CASPASE 3; CASPASE 9; CASPASE INHIBITORS; CELL LINE; CELL PROLIFERATION; DRUGS, CHINESE HERBAL; HEPATIC STELLATE CELLS; HUMANS; LIVER CIRRHOSIS; MITOCHONDRIA; OLEANOLIC ACID; OLIGOPEPTIDES; RATS; SAPONINS; TRITERPENES;

EID: 84983337851     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-016-2599-0     Document Type: Article

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