메뉴 건너뛰기




Volumn 16, Issue 9, 2013, Pages 793-800

Saikosaponin a and saikosaponin d inhibit proliferation and migratory activity of rat HSC-T6 cells

Author keywords

PDGF; Rat hepatic stellate cells; Saikosaponin; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR 1; SAIKOSAPONIN A; SAIKOSAPONIN D; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA 1 RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

EID: 84884506665     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2013.2762     Document Type: Article
Times cited : (48)

References (27)
  • 1
    • 0033061550 scopus 로고    scopus 로고
    • Vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation
    • Ikeda K, Wakahara T, Wang YQ, Kadoya H, Kawada N, Kaneda K: In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation. Hepatology 1999; 29:1760-1767
    • (1999) Hepatology , vol.29 , pp. 1760-1767
    • Ikeda, K.1    Wakahara, T.2    Wang, Y.Q.3    Kadoya, H.4    Kawada, N.5    Kaneda, K.6
  • 3
    • 2642517210 scopus 로고    scopus 로고
    • Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis
    • Borkham-Kamphorst E, Herrmann J, Stoll D, Treptau J, Gressner AM, Weiskirchen R: Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis. Lab Invest 2004;84:766-777
    • (2004) Lab Invest , vol.84 , pp. 766-777
    • Borkham-Kamphorst, E.1    Herrmann, J.2    Stoll, D.3    Treptau, J.4    Gressner, A.M.5    Weiskirchen, R.6
  • 4
    • 33645960124 scopus 로고    scopus 로고
    • Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis
    • Liu X, Hu H, Yin JQ: Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis. Liver Int 2006;26:8-22
    • (2006) Liver Int , vol.26 , pp. 8-22
    • Liu, X.1    Hu, H.2    Yin, J.Q.3
  • 5
    • 25844455319 scopus 로고    scopus 로고
    • Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line
    • Wang XM, Yu DM, McCaughan GW, Gorrell MD: Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line. Hepatology 2005;42: 935-945
    • (2005) Hepatology , vol.42 , pp. 935-945
    • Wang, X.M.1    Yu, D.M.2    McCaughan, G.W.3    Gorrell, M.D.4
  • 7
    • 0141705407 scopus 로고    scopus 로고
    • Cytotoxicity and anti-hepatitis b virus activities of saikosaponins from bupleurum species
    • Chiang LC, Ng LT, Liu LT, Shieh DE, Lin CC: Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species. Planta Med 2003;69:705-709
    • (2003) Planta Med , vol.69 , pp. 705-709
    • Chiang, L.C.1    Ng, L.T.2    Liu, L.T.3    Shieh, D.E.4    Lin, C.C.5
  • 11
    • 0026547720 scopus 로고
    • Inactivation of measles virus and herpes simplex virus by saikosaponin d
    • Ushio Y, Abe H: Inactivation of measles virus and herpes simplex virus by saikosaponin d. Planta Med 1992;58:171-173
    • (1992) Planta Med , vol.58 , pp. 171-173
    • Ushio, Y.1    Abe, H.2
  • 12
    • 66449117042 scopus 로고    scopus 로고
    • Cytotoxic activity and inhibitory effect on nitric oxide production of triterpene saponins from the roots of physospermum verticillatum (waldst & kit apiaceae
    • Tundis R, Bonesi M, Deguin B, Loizzo MR, Menichini F, Conforti F, Tillequin F, Menichini F: Cytotoxic activity and inhibitory effect on nitric oxide production of triterpene saponins from the roots of Physospermum verticillatum (Waldst & Kit)(Apiaceae). Bioorg Med Chem 2009;17:4542-4547
    • (2009) Bioorg Med Chem , vol.17 , pp. 4542-4547
    • Tundis, R.1    Bonesi, M.2    Deguin, B.3    Loizzo, M.R.4    Menichini, F.5    Conforti, F.6    Tillequin, F.7    Menichini, F.8
  • 13
    • 3042541878 scopus 로고    scopus 로고
    • The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells
    • Hsu YL, Kuo PL, Lin CC: The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells. Life Sci 2004;75:1231-1242
    • (2004) Life Sci , vol.75 , pp. 1231-1242
    • Hsu, Y.L.1    Kuo, P.L.2    Lin, C.C.3
  • 14
    • 4344636755 scopus 로고    scopus 로고
    • Involvement of p53, nuclear factor kappaB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines
    • Hsu YL, Kuo PL, Chiang LC, Lin CC: Involvement of p53, nuclear factor kappaB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines. Cancer Lett 2004;213:213-221
    • (2004) Cancer Lett , vol.213 , pp. 213-221
    • Hsu, Y.L.1    Kuo, P.L.2    Chiang, L.C.3    Lin, C.C.4
  • 15
    • 9644290789 scopus 로고    scopus 로고
    • Saikosaponin-A induces apoptotic mechanism in human breast MDA-MB-231 and MCF-7 cancer cells
    • Chen JC, Chang NW, Chung JG, Chen KC: Saikosaponin-A induces apoptotic mechanism in human breast MDA-MB-231 and MCF-7 cancer cells. Am J Chin Med 2003;31:363-377
    • (2003) Am J Chin Med , vol.31 , pp. 363-377
    • Chen, J.C.1    Chang, N.W.2    Chung, J.G.3    Chen, K.C.4
  • 16
    • 0028110031 scopus 로고
    • Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines
    • Motoo Y, Sawabu N: Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines. Cancer Lett 1994;86:91-95
    • (1994) Cancer Lett , vol.86 , pp. 91-95
    • Motoo, Y.1    Sawabu, N.2
  • 17
    • 46749151009 scopus 로고    scopus 로고
    • Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats
    • Wu SJ, Lin YH, Chu CC, Tsai YH, Chao JC: Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats. J Med Food 2008; 11:224-229
    • (2008) J Med Food , vol.11 , pp. 224-229
    • Wu, S.J.1    Lin, Y.H.2    Chu, C.C.3    Tsai, Y.H.4    Chao, J.C.5
  • 18
    • 34249673939 scopus 로고    scopus 로고
    • GongY: Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury
    • Fan J, Li X, Li P, Li N,Wang T, ShenH, SiowY,Choy P, GongY: Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury. Biochem Cell Biol 2007;85:189-195
    • (2007) Biochem Cell Biol , vol.85 , pp. 189-195
    • Fan, J.1    Li, X.2    Li, P.3    Li, N.4    Wang, T.5    Shen H Siow, Y.6    Choy, P.7
  • 19
    • 79961131550 scopus 로고    scopus 로고
    • Vitro anti-influenza A H1N1 effect of extract of Bupleuri Radix
    • Wen S, Huifu X, Hao H: In vitro anti-influenza A H1N1 effect of extract of Bupleuri Radix. Immunopharmacol Immunotoxicol 2011;33:433-437
    • (2011) Immunopharmacol Immunotoxicol , vol.33 , pp. 433-437
    • Wen, S.1    Huifu, X.2    Hao, H.3
  • 20
    • 0032973564 scopus 로고    scopus 로고
    • B-cell proliferation activity of pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. and its structural requirement
    • Sakurai MH, Matsumoto T, Kiyohara H, Yamada H: B-cell proliferation activity of pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. and its structural requirement. Immunology 1999;97:540-547
    • (1999) Immunology , vol.97 , pp. 540-547
    • Sakurai, M.H.1    Matsumoto, T.2    Kiyohara, H.3    Yamada, H.4
  • 21
    • 0025734218 scopus 로고
    • Effect of saikosaponin on the immune responses in mice
    • Ushio Y, Oda Y, Abe H: Effect of saikosaponin on the immune responses in mice. Int J Immunopharmacol 1991;13:501-508
    • (1991) Int J Immunopharmacol , vol.13 , pp. 501-508
    • Ushio, Y.1    Oda, Y.2    Abe, H.3
  • 24
    • 70349556686 scopus 로고    scopus 로고
    • Therapeutic targeting of the PDGF and TGF-beta-signaling pathways in hepatic stellate cells by PTK787/ZK22258
    • Liu Y, Wen XM, Lui EL, Friedman SL, Cui W, Ho NP, Li L, Ye T, Fan ST, Zhang H: Therapeutic targeting of the PDGF and TGF-beta-signaling pathways in hepatic stellate cells by PTK787/ZK22258. Lab Invest 2009;89:1152-1160
    • (2009) Lab Invest , vol.89 , pp. 1152-1160
    • Liu, Y.1    Wen, X.M.2    Lui, E.L.3    Friedman, S.L.4    Cui, W.5    Ho, N.P.6    Li, L.7    Ye, T.8    Fan, S.T.9    Zhang, H.10
  • 25
    • 0031225015 scopus 로고    scopus 로고
    • Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts
    • Grotendorst GR: Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev 1997;8:171-179
    • (1997) Cytokine Growth Factor Rev , vol.8 , pp. 171-179
    • Grotendorst, G.R.1
  • 26
    • 78049382168 scopus 로고    scopus 로고
    • Effect of salvianolic-acid B on inhibiting MAPK signaling induced by transforming growth factor-b1 in activated rat hepatic stellate cells
    • Lv Z, Song Y, Xue D, Zhang W, Cheng Y, Xu L: Effect of salvianolic-acid B on inhibiting MAPK signaling induced by transforming growth factor-b1 in activated rat hepatic stellate cells. J Ethnopharmacol 2010;132:384-392
    • (2010) J Ethnopharmacol , Issue.132 , pp. 384-392
    • Lv, Z.1    Song, Y.2    Xue, D.3    Zhang, W.4    Cheng, Y.5    Xu, L.6
  • 27
    • 27744479643 scopus 로고    scopus 로고
    • Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells
    • Le Pabic H, L'Helgoualc'h A, Coutant A, Wewer UM, Baffet G, Clément B, Théret N: Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells. J Hepatol 2005;43:1038-1044
    • (2005) J Hepatol , vol.43 , pp. 1038-1044
    • Le Pabic, H.1    L'Helgoualc'h, A.2    Coutant, A.3    Wewer, U.M.4    Baffet, G.5    Clément, B.6    Théret, N.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.