메뉴 건너뛰기




Volumn 9, Issue 11, 2002, Pages 1240-1247

The proapoptotic BH3-only protein BAD transduces cell death signals independently of its interaction with Bcl-2

Author keywords

Apoptosis; BAD; Bcl 2 family; BH3 domain; Phosphorylation

Indexed keywords

ASPARTIC ACID; GLYCINE; MUTANT PROTEIN; PROTEIN BAD; PROTEIN BCL 2; PROTEIN BCL XL; BAD PROTEIN, HUMAN; BCL2L1 PROTEIN, HUMAN; CARRIER PROTEIN; PROTEIN BCL X;

EID: 0036848317     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401097     Document Type: Article
Times cited : (48)

References (33)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams JM and Cory S (1998) The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A, McDonnell JM and Korsmeyer SJ (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13: 1899-1911
    • (1999) Genes Dev , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 3
    • 0032146987 scopus 로고    scopus 로고
    • Bcl-2-family proteins: The role of the BH3 domain in apoptosis
    • Kelekar A and Thompson CB (1998) Bcl-2-family proteins: the role of the BH3 domain in apoptosis. Trends Cell Biol. 8: 267-271
    • (1998) Trends Cell Biol , vol.8 , pp. 267-271
    • Kelekar, A.1    Thompson, C.B.2
  • 6
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
    • Yang E, Zha J, Jockel J, Boise LH, Thompson CB and Korsmeyer SJ (1995) Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80: 285-291
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockel, J.3    Boise, L.H.4    Thompson, C.B.5    Korsmeyer, S.J.6
  • 7
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL
    • Zha J, Harada H, Yang E, Jockel J and Korsmeyer SJ (1996) Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL. Cell 87: 619-628
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 10
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID bycaspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ and Yuan J (1998) Cleavage of BID bycaspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94: 491-501
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 11
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budilhardjo I, Zou H, Slaughter C and Wang X (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94: 481-490
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budilhardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 13
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • Zong W-X, Lindsten T, Ross AJ, MacGregor GR and Thompson CB (2001) BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev. 15: 1481-1486
    • (2001) Genes Dev , vol.15 , pp. 1481-1486
    • Zong, W.-X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5
  • 14
    • 0035886878 scopus 로고    scopus 로고
    • Survival-factor-induced phosphorylation of Bad results in its dissociation from Bcl-x(L) but not Bcl-2
    • Hirai I and Wang H-G (2001) Survival-factor-induced phosphorylation of Bad results in its dissociation from Bcl-x(L) but not Bcl-2. Biochem. J. 359: 345-352
    • (2001) Biochem. J , vol.359 , pp. 345-352
    • Hirai, I.1    Wang, H.-G.2
  • 16
    • 0035844867 scopus 로고    scopus 로고
    • Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis
    • Nechushtan A, Smith CL, Lamensdorf I, Yoon S-H and Youle RJ (2001) Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis. J. Cell Biol. 153: 1265-1276
    • (2001) J. Cell Biol , vol.153 , pp. 1265-1276
    • Nechushtan, A.1    Smith, C.L.2    Lamensdorf, I.3    Yoon, S.-H.4    Youle, R.J.5
  • 17
    • 0030695837 scopus 로고    scopus 로고
    • Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL
    • Kelekar A, Chang BS, Harlan JE, Fesik SW and Thompson CB (1997) Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL. Mol. Cell. Biol. 17: 7040-7046
    • (1997) Mol. Cell. Biol , vol.17 , pp. 7040-7046
    • Kelekar, A.1    Chang, B.S.2    Harlan, J.E.3    Fesik, S.W.4    Thompson, C.B.5
  • 19
    • 0034904755 scopus 로고    scopus 로고
    • BAD induces apoptosis in cells over-expressing Bcl-2 or Bcl-xL without loss of mitochondrial membrane potential
    • Schimmer AD, Hedley DW, Pham NA, Chow S and Minden MD. (2001) BAD induces apoptosis in cells over-expressing Bcl-2 or Bcl-xL without loss of mitochondrial membrane potential. Leuk Lymphoma 42: 429-443
    • (2001) Leuk. Lymphoma , vol.42 , pp. 429-443
    • Schimmer, A.D.1    Hedley, D.W.2    Pham, N.A.3    Chow, S.4    Minden, M.D.5
  • 21
    • 0033525591 scopus 로고    scopus 로고
    • Solution structure of BID, an intracellular amplifier of apoptotic signaling
    • Chou JJ, Li H, Salvesen GS, Yuan J and Wagner G (1999) Solution structure of BID, an intracellular amplifier of apoptotic signaling. Cell 96: 615-624
    • (1999) Cell , vol.96 , pp. 615-624
    • Chou, J.J.1    Li, H.2    Salvesen, G.S.3    Yuan, J.4    Wagner, G.5
  • 22
    • 0033525749 scopus 로고    scopus 로고
    • Solution structure of the proapoptotic molecule BID: A structural basis for apoptotic agonists and antagonists
    • McDonnell JM, Fushman D, Milliman CL, Korsmeyer SJ and Cowburn D (1999) Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists. Cell 96: 625-634
    • (1999) Cell , vol.96 , pp. 625-634
    • McDonnell, J.M.1    Fushman, D.2    Milliman, C.L.3    Korsmeyer, S.J.4    Cowburn, D.5
  • 24
    • 0031660082 scopus 로고    scopus 로고
    • Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing
    • Wang K, Gross A, Waksman G and Korsmeyer SJ (1998) Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing. Mol. Cell Biol. 18: 6083-6089
    • (1998) Mol. Cell Biol , vol.18 , pp. 6083-6089
    • Wang, K.1    Gross, A.2    Waksman, G.3    Korsmeyer, S.J.4
  • 30
    • 0024507215 scopus 로고
    • Construction of mutant and chimeric genes using the polymerase chain reaction
    • Vallette F, Mege E, Reiss A and Milton A (1989) Construction of mutant and chimeric genes using the polymerase chain reaction. Nucleic Acid Res. 17: 723-733
    • (1989) Nucleic Acid Res , vol.17 , pp. 723-733
    • Vallette, F.1    Mege, E.2    Reiss, A.3    Milton, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.