microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway

Oncotarget

Volumn 6, Issue 9, 2015, Pages 7325-7338

  Wang, Jia ^a   Chu, Eagle S H ^a   Chen, Hai Yong ^a   Man, Kwan ^b   Go, Minnie Y Y ^a   Huang, Xiao Ru ^a   Lan, Hui Yao ^a   Sung, Joseph J Y ^a   Yu, Jun ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

AKT3; Hepatic stellate cell; Liver fibrosis; miR 29b

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CARBON TETRACHLORIDE; CASPASE 9; COLLAGEN TYPE 1; CYCLIN D1; MICRORNA 29B; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P21; SMAD3 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; 3' UNTRANSLATED REGION; MADH3 PROTEIN, RAT; MICRORNA; MIRN29 MICRORNA, HUMAN; MIRN29 MICRORNA, MOUSE; MIRN29 MICRORNA, RAT; SMAD3 PROTEIN, HUMAN; SMAD3 PROTEIN, MOUSE;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL GROWTH; CELL VIABILITY; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; FIBROGENESIS; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE REPRESSION; GENE SILENCING; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION; STELLATE CELL; ANIMAL; BIOPSY; C57BL MOUSE; CYTOLOGY; GENE EXPRESSION PROFILING; GENETICS; HEPATIC STELLATE CELL; LIVER; LIVER CIRRHOSIS; MALE; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

3' UNTRANSLATED REGIONS; ANIMALS; APOPTOSIS; BIOPSY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATIC STELLATE CELLS; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMAD3 PROTEIN;

EID: 84927144458     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2621     Document Type: Article

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