Cytotoxic activity and inhibitory effect on nitric oxide production of triterpene saponins from the roots of Physospermum verticillatum (Waldst & Kit) (Apiaceae)

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 13, 2009, Pages 4542-4547

  Tundis, Rosa ^a   Bonesi, Marco ^a   Deguin, Brigitte ^b   Loizzo, Monica R ^a   Menichini, Federica ^a   Conforti, Filomena ^a   Tillequin, François ^b   Menichini, Francesco ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

^b FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

Author keywords

Apiaceae; Cytotoxic activity; Inhibition of NO production; Triterpene saponins

Indexed keywords

BUDDLESAPONIN IV; NITRIC OXIDE; SAIKOSAPOGENIN A; SAIKOSAPONIN A; SAPONIN DERIVATIVE; SONGAROSAPONIN D; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; APIALES; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHYSOSPERMUM VERTICILLATUM; PLANT ROOT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APIACEAE; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MACROPHAGES; MICE; NEOPLASMS; NITRIC OXIDE; OLEANOLIC ACID; PLANT ROOTS; SAPONINS; TRITERPENES;

APIACEAE; PHYSOSPERMUM;

EID: 66449117042     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.05.006     Document Type: Article

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