Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4

Journal of Hepatology

Volumn 63, Issue 3, 2015, Pages 697-704

  Out, Carolien ^a   Patankar, Jay V ^b,c   Doktorova, Marcela ^a   Boesjes, Marije ^a   Bos, Trijnie ^a   De Boer, Sanna ^a   Havinga, Rick ^a   Wolters, Henk ^a   Boverhof, Renze ^a   Van Dijk, Theo H ^a   Smoczek, Anna ^d   Bleich, André ^d   Sachdev, Vinay ^b   Kratky, Dagmar ^b   Kuipers, Folkert ^a   Verkade, Henkjan J ^a   Groen, Albert K ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Antibiotic treatment; Asbt; Bile acid reabsorption; Bile acid synthesis; Cyp7a1; Enterohepatic circulation; Fgf15; Gata4; Germfree; Gut microbiota; Intestinal bacteria

Indexed keywords

APICAL SODIUM DEPENDENT BILE ACID TRANSPORTER; BACITRACIN; BILE ACID; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; NEOMYCIN; PHOSPHOLIPID; SODIUM BILE ACID COTRANSPORTER; TRANSCRIPTION FACTOR GATA 4; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; COTRANSPORTER; CYP7A1 PROTEIN, MOUSE; GATA4 PROTEIN, MOUSE; MESSENGER RNA; ORGANIC ANION TRANSPORTER; SODIUM-BILE ACID COTRANSPORTER;

ANIMAL EXPERIMENT; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL FLORA; BILE ACID METABOLISM; BILE ACID SYNTHESIS; CONTROLLED STUDY; ENTEROHEPATIC CIRCULATION; HOMEOSTASIS; ILEUM; INTESTINE FLORA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; GENETICS; INTESTINE ABSORPTION; MALE; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTI-BACTERIAL AGENTS; BILE ACIDS AND SALTS; CHOLESTEROL 7-ALPHA-HYDROXYLASE; GASTROINTESTINAL MICROBIOME; GATA4 TRANSCRIPTION FACTOR; HOMEOSTASIS; INTESTINAL ABSORPTION; MALE; MICE; MICE, INBRED C57BL; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; RNA, MESSENGER; SYMPORTERS;

EID: 84983110883     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.04.030     Document Type: Article

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