GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice

Gastroenterology

Volumn 140, Issue 4, 2011, Pages 1219-1229.e2

  Beuling, Eva ^a   Baffour Awuah, Nana Yaa A ^a   Stapleton, Kelly A ^a   Aronson, Boaz E ^a   Noah, Taeko K ^b   Shroyer, Noah F ^b   Duncan, Stephen A ^c   Fleet, James C ^d   Krasinski, Stephen D ^a,e  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d PURDUE UNIVERSITY   (United States)

^e TUFTS UNIVERSITY   (United States)

Author keywords

Crypt Cell Proliferation; GATA4; GATA6; Intestinal Differentiation

Indexed keywords

TRANSCRIPTION FACTOR GATA; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CRYPT CELL; DUODENUM; GATA4 GENE; GATA6 GENE; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GOBLET CELL; ILEUM; INTESTINE ABSORPTION; INTESTINE CELL; JEJUNUM; MALE; MOUSE; NONHUMAN; PANETH CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SMALL INTESTINE;

EID: 79953187258     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.01.033     Document Type: Article

References (49)

1. T.S. Stappenbeck, M.H. Wong, and J.R. Saam Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium Curr Opin Cell Biol 10 1998 702 709 (Pubitemid 28561013)
2. H. Ireland, R. Kemp, and C. Houghton Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin Gastroenterology 126 2004 1236 1246 (Pubitemid 38552788)
3. V. Korinek, N. Barker, and P. Moerer Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 Nat Genet 19 1998 379 383 (Pubitemid 28357912)
4. F. Kuhnert, C.R. Davis, and H.T. Wang Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1 Proc Natl Acad Sci U S A 101 2004 266 271 (Pubitemid 38084239)
5. D. Pinto, A. Gregorieff, and H. Begthel Canonical Wnt signals are essential for homeostasis of the intestinal epithelium Genes Dev 17 2003 1709 1713 (Pubitemid 36870334)
6. M. van de Wetering, E. Sancho, and C. Verweij The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells Cell 111 2002 241 250 (Pubitemid 35292444)
7. P. Andreu, S. Colnot, and C. Godard Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine Development 132 2005 1443 1451 (Pubitemid 40528801)
8. C. Crosnier, N. Vargesson, and S. Gschmeissner Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine Development 132 2005 1093 1104 (Pubitemid 40484942)
9. O. Riccio, M.E. van Gijn, and A.C. Bezdek Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2 EMBO Rep 9 2008 377 383
10. J.H. van Es, M.E. van Gijn, and O. Riccio Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells Nature 435 2005 959 963 (Pubitemid 40896322)
11. G.T. Wong, D. Manfra, and F.M. Poulet Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation J Biol Chem 279 2004 12876 12882 (Pubitemid 38445862)
12. S. Fre, M. Huyghe, and P. Mourikis Notch signals control the fate of immature progenitor cells in the intestine Nature 435 2005 964 968 (Pubitemid 40896323)
13. J. Jensen, E.E. Pedersen, and P. Galante Control of endodermal endocrine development by Hes-1 Nat Genet 24 2000 36 44 (Pubitemid 30041417)
14. Q. Yang, N.A. Bermingham, and M.J. Finegold Requirement of Math1 for secretory cell lineage commitment in the mouse intestine Science 294 2001 2155 2158 (Pubitemid 33150670)
15. J.D. Molkentin The zinc finger-containing transcription factors GATA-4, -5, and -6 Ubiquitously expressed regulators of tissue-specific gene expression J Biol Chem 275 2000 38949 38952 (Pubitemid 32058903)
16. T. Bosse, C.M. Piaseckyj, and E. Burghard Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine Mol Cell Biol 26 2006 9060 9070 (Pubitemid 44851961)
17. J.K. Divine, L.J. Staloch, and H. Haveri GATA-4, GATA-5, and GATA-6 activate the rat liver fatty acid binding protein gene in concert with HNF-1alpha Am J Physiol Gastrointest Liver Physiol 287 2004 G1086 G1099
18. H. Haveri, M. Westerholm-Ormio, and K. Lindfors Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa BMC Gastroenterol 8 2008 9
19. H.M. van Wering, T. Bosse, and A. Musters Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4 Am J Physiol Gastrointest Liver Physiol 287 2004 G899 G909
20. C.P. Sodhi, J. Li, and S.A. Duncan Generation of mice harbouring a conditional loss-of-function allele of Gata6 BMC Dev Biol 6 2006 19
21. M.A. Battle, B.J. Bondow, and M.A. Iverson GATA4 is essential for jejunal function in mice Gastroenterology 135 2008 1676 1686 e1
22. E. Beuling, I.M. Kerkhof, and G.A. Nicksa Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine Gut 59 2010 888 895
23. F. el Marjou, K.P. Janssen, and B.H. Chang Tissue-specific and inducible Cre-mediated recombination in the gut epithelium Genesis 39 2004 186 193 (Pubitemid 39079517)
24. E. Beuling, T. Bosse, and D.J. aan de Kerk GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors Dev Biol 322 2008 179 189
25. T. Bosse, J.J. Fialkovich, and C.M. Piaseckyj Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development Am J Physiol Gastrointest Liver Physiol 292 2007 G1302 G1314
26. J.F. Trahair, M.R. Neutra, and J.I. Gordon Use of transgenic mice to study the routing of secretory proteins in intestinal epithelial cells: analysis of human growth hormone compartmentalization as a function of cell type and differentiation J Cell Biol 109 1989 3231 3242 (Pubitemid 20017975)
27. J.H. van Es, P. Jay, and A. Gregorieff Wnt signalling induces maturation of Paneth cells in intestinal crypts Nat Cell Biol 7 2005 381 386 (Pubitemid 40533127)
28. E. Batlle, J.T. Henderson, and H. Beghtel Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB Cell 111 2002 251 263 (Pubitemid 35292445)
29. P. Bastide, C. Darido, and J. Pannequin Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium J Cell Biol 178 2007 635 648 (Pubitemid 47267275)
30. Y. Mori-Akiyama, M. van den Born, and J.H. van Es SOX9 is required for the differentiation of paneth cells in the intestinal epithelium Gastroenterology 133 2007 539 546 (Pubitemid 47187347)
31. M. Jenny, C. Uhl, and C. Roche Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium EMBO J 21 2002 6338 6347 (Pubitemid 35448412)
32. N.F. Shroyer, D. Wallis, and K.J. Venken Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation Genes Dev 19 2005 2412 2417 (Pubitemid 41483688)
33. T.K. Noah, A. Kazanjian, and J. Whitsett SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells Exp Cell Res 316 2010 452 465
34. A. Gregorieff, D.E. Stange, and P. Kujala The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium Gastroenterology 137 2009 1333 1345 e1-3
35. S. Agnihotri, A. Wolf, and D. Picard GATA4 is a regulator of astrocyte cell proliferation and apoptosis in the human and murine central nervous system Oncogene 28 2009 3033 3046
36. S. Ezoe, I. Matsumura, and S. Nakata GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through accumulation of p21(WAF1) and p27(Kip1) proteins Blood 100 2002 3512 3520 (Pubitemid 35303918)
37. H. Perlman, E. Suzuki, and M. Simonson GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest J Biol Chem 273 1998 13713 13718 (Pubitemid 28268418)
38. A. Rojas, S.W. Kong, and P. Agarwal GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium Mol Cell Biol 28 2008 5420 5431
39. M. Rylski, J.J. Welch, and Y.Y. Chen GATA-1-mediated proliferation arrest during erythroid maturation Mol Cell Biol 23 2003 5031 5042 (Pubitemid 36793347)
40. P. Andreu, G. Peignon, and C. Slomianny A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation Dev Biol 324 2008 288 296 (Pubitemid 50321508)
41. L.G. van der Flier, and H. Clevers Stem cells, self-renewal, and differentiation in the intestinal epithelium Annu Rev Physiol 71 2009 241 260
42. E. Beuling, I.M. Kerkhof, and G.A. Nicksa Conditional Gata4 deletion in mice induces bile acid absorption in the proximal intestine Gut 59 2010 888 895
43. T. Bosse, C.M. Piaseckyj, and E. Burghard Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine Mol Cell Biol 26 2006 9060 9070 (Pubitemid 44851961)
44. F. el Marjou, K.P. Janssen, and B.H. Chang Tissue-specific and inducible Cre-mediated recombination in the gut epithelium Genesis 39 2004 186 193 (Pubitemid 39079517)
45. C.P. Sodhi, J. Li, and S.A. Duncan Generation of mice harbouring a conditional loss-of-function allele of Gata6 BMC Dev Biol 6 2006 19
46. E. Beuling, T. Bosse, and D.J. aan de Kerk GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors Dev Biol 322 2008 179 189
47. B.M. Bolstad, R.A. Irizarry, and M. Astrand A comparison of normalization methods for high density oligonucleotide array data based on variance and bias Bioinformatics 19 2003 185 193 (Pubitemid 36181903)
48. Y. Benjamini, and Y. Hochberg Controlling false discovery rate: a practical and powerful approach to multiple testing J Royal Stat Soc B 57 1995 289 300
49. M.B. Eisen, P.T. Spellman, and P.O. Brown Cluster analysis and display of genome-wide expression patterns Proc Natl Acad Sci U S A 95 1998 14863 14868 (Pubitemid 29003722)