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Volumn 10, Issue JUL, 2016, Pages

Effects of cannabidiol and hypothermia on short-term brain damage in new-born piglets after acute hypoxia-ischemia

Author keywords

Cannabidiol; Hypothermia; Hypoxic ischemic encephalopathy; Neonatal brain; Neurodevelopment; Neuroprotection; Newborn animal

Indexed keywords

CANNABIDIOL; CASPASE 3; GLUTAMIC ACID; LACTIC ACID; N ACETYLASPARTIC ACID; TUMOR NECROSIS FACTOR ALPHA;

EID: 84983050314     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2016.00323     Document Type: Article
Times cited : (58)

References (34)
  • 1
    • 0035487313 scopus 로고    scopus 로고
    • Cytokines and acute neurodegeneration
    • Allan, S. M., and Rothwell, N. J. (2001). Cytokines and acute neurodegeneration. Nat. Rev. Neurosci. 2, 734-740. doi: 10.1038/35094583
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 734-740
    • Allan, S.M.1    Rothwell, N.J.2
  • 2
    • 57849168951 scopus 로고    scopus 로고
    • Neuroprotective effects of the non-psychoactive cannabinoid cannabidiol in hypoxic-ischemic newborn piglets
    • Alvarez, F. J., Lafuente, H., Rey, M. C., Mielgo, V. E., Gastiasoro, E., Rueda, M., et al. (2008). Neuroprotective effects of the non-psychoactive cannabinoid cannabidiol in hypoxic-ischemic newborn piglets. Pediatr. Res. 64, 653-658. doi: 10.1203/PDR.0b013e318186e5dd
    • (2008) Pediatr. Res. , vol.64 , pp. 653-658
    • Alvarez, F.J.1    Lafuente, H.2    Rey, M.C.3    Mielgo, V.E.4    Gastiasoro, E.5    Rueda, M.6
  • 3
    • 72749107868 scopus 로고    scopus 로고
    • The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB2 and adenosine receptors
    • Castillo, A., Tolón, M. R., Fernández-Ruiz, J., Romero, J., and Martínez-Orgado, J. (2010). The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB2 and adenosine receptors. Neurobiol. Dis. 37, 434-440. doi: 10.1016/j.nbd.2009.10.023
    • (2010) Neurobiol. Dis. , vol.37 , pp. 434-440
    • Castillo, A.1    Tolón, M.R.2    Fernández-Ruiz, J.3    Romero, J.4    Martínez-Orgado, J.5
  • 4
    • 77956364049 scopus 로고    scopus 로고
    • Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs
    • Chakkarapani, E., Dingley, J., Liu, X., Hoque, N., Aquilina, K., Porter, H., et al. (2010). Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs. Ann. Neurol. 68, 330-341. doi: 10.1002/ana.22016
    • (2010) Ann. Neurol. , vol.68 , pp. 330-341
    • Chakkarapani, E.1    Dingley, J.2    Liu, X.3    Hoque, N.4    Aquilina, K.5    Porter, H.6
  • 5
    • 77955982977 scopus 로고    scopus 로고
    • Synergistic neuroprotective therapies with hypothermia
    • Cilio, M. R., and Ferriero, D. M. (2010). Synergistic neuroprotective therapies with hypothermia. Semin. Neonatal Fetal Med. 15, 293-298. doi: 10.1016/j.siny.2010.02.002
    • (2010) Semin. Neonatal Fetal Med. , vol.15 , pp. 293-298
    • Cilio, M.R.1    Ferriero, D.M.2
  • 6
    • 84893813508 scopus 로고    scopus 로고
    • Mechanisms of hypothermic neuroprotection
    • Drury, P. P., Gunn, E. R., Bennet, L., and Gunn, A. J. (2014). Mechanisms of hypothermic neuroprotection. Clin. Perinatol. 41, 161-175. doi: 10.1016/j.clp.2013.10.005
    • (2014) Clin. Perinatol. , vol.41 , pp. 161-175
    • Drury, P.P.1    Gunn, E.R.2    Bennet, L.3    Gunn, A.J.4
  • 7
    • 34547145165 scopus 로고    scopus 로고
    • G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences
    • Faul, F., Erdfelder, E., Lang, A.-G., and Buchner, A. (2007). G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav. Res. Methods 39, 175-191. doi: 10.3758/BF03193146
    • (2007) Behav. Res. Methods , vol.39 , pp. 175-191
    • Faul, F.1    Erdfelder, E.2    Lang, A.-G.3    Buchner, A.4
  • 8
    • 79960834102 scopus 로고    scopus 로고
    • Xenon augmented hypothermia reduces early lactate/N-acetylaspartate and cell death in perinatal asphyxia
    • Faulkner, S., Bainbridge, A., Kato, T., Chandrasekaran, M., Kapetanakis, A. B., Hristova, M., et al. (2011). Xenon augmented hypothermia reduces early lactate/N-acetylaspartate and cell death in perinatal asphyxia. Ann. Neurol. 70, 133-150. doi: 10.1002/ana.22387
    • (2011) Ann. Neurol. , vol.70 , pp. 133-150
    • Faulkner, S.1    Bainbridge, A.2    Kato, T.3    Chandrasekaran, M.4    Kapetanakis, A.B.5    Hristova, M.6
  • 10
    • 80255134519 scopus 로고    scopus 로고
    • White matter protection with insulin like-growth factor 1 (IGF-1) and hypothermia is not additive after severe reversible cerebral ischemia in term fetal sheep
    • George, S., Bennet, L., Weaver-Mikaere, L., Fraser, M., Bouwmans, J., Mathai, S., et al. (2011). White matter protection with insulin like-growth factor 1 (IGF-1) and hypothermia is not additive after severe reversible cerebral ischemia in term fetal sheep. Dev. Neurosci. 33, 280-287. doi: 10.1159/000329923
    • (2011) Dev. Neurosci. , vol.33 , pp. 280-287
    • George, S.1    Bennet, L.2    Weaver-Mikaere, L.3    Fraser, M.4    Bouwmans, J.5    Mathai, S.6
  • 11
    • 0035084572 scopus 로고    scopus 로고
    • Glutamate in cerebral tissue of asphyxiated neonates during the first week of life demonstrated in vivo using proton magnetic resonance spectroscopy
    • Groenendaal, F., Roelants-Van Rijn, A. M., van Der Grond, J., Toet, M. C., and de Vries, L. S. (2001). Glutamate in cerebral tissue of asphyxiated neonates during the first week of life demonstrated in vivo using proton magnetic resonance spectroscopy. Biol. Neonate 79, 254-257. doi: 10.1159/000047101
    • (2001) Biol. Neonate , vol.79 , pp. 254-257
    • Groenendaal, F.1    Roelants-Van Rijn, A.M.2    van Der Grond, J.3    Toet, M.C.4    de Vries, L.S.5
  • 12
    • 0032493197 scopus 로고    scopus 로고
    • Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants
    • Hampson, A. J., Grimaldi, M., Axelrod, J., and Wink, D. (1998). Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proc. Natl. Acad. Sci. U.S.A. 95, 8268-8273. doi: 10.1073/pnas.95.14.8268
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 8268-8273
    • Hampson, A.J.1    Grimaldi, M.2    Axelrod, J.3    Wink, D.4
  • 14
    • 84867093051 scopus 로고    scopus 로고
    • Serum cytokines in a clinical trial of hypothermia for neonatal hypoxic-ischemic encephalopathy
    • Jenkins, D. D., Rollins, L. G., Perkel, J. K., Wagner, C. L., Katikaneni, L. P., Bass, W. T., et al. (2012). Serum cytokines in a clinical trial of hypothermia for neonatal hypoxic-ischemic encephalopathy. J. Cereb. Blood Flow Metab. 32, 1888-1896. doi: 10.1038/jcbfm.2012.83
    • (2012) J. Cereb. Blood Flow Metab. , vol.32 , pp. 1888-1896
    • Jenkins, D.D.1    Rollins, L.G.2    Perkel, J.K.3    Wagner, C.L.4    Katikaneni, L.P.5    Bass, W.T.6
  • 16
    • 79952722818 scopus 로고    scopus 로고
    • Treatment advances in neonatal neuroprotection and neurointensive care
    • Johnston, M. V., Fatemi, A., Wilson, M. A., and Northington, F. (2011). Treatment advances in neonatal neuroprotection and neurointensive care. Lancet Neurol. 10, 372-382. doi: 10.1016/S1474-4422(11)70016-3
    • (2011) Lancet Neurol. , vol.10 , pp. 372-382
    • Johnston, M.V.1    Fatemi, A.2    Wilson, M.A.3    Northington, F.4
  • 17
    • 84864549499 scopus 로고    scopus 로고
    • Prolonged gaseous hypothermia prevents the upregulation of phagocytosis-specific protein annexin 1 and causes low-amplitude EEG activity in the aged rat brain after cerebral ischemia
    • Joseph, C., Buga, A. M., Vintilescu, R., Balseanu, A. T., Moldovan, M., Junker, H., et al. (2012). Prolonged gaseous hypothermia prevents the upregulation of phagocytosis-specific protein annexin 1 and causes low-amplitude EEG activity in the aged rat brain after cerebral ischemia. J. Cereb. Blood Flow Metab. 32, 1532-1642. doi: 10.1038/jcbfm.2012.65
    • (2012) J. Cereb. Blood Flow Metab. , vol.32 , pp. 1532-1642
    • Joseph, C.1    Buga, A.M.2    Vintilescu, R.3    Balseanu, A.T.4    Moldovan, M.5    Junker, H.6
  • 18
    • 84893719497 scopus 로고    scopus 로고
    • Pharmacologic neuroprotective strategies in neonatal brain injury
    • Juul, S. E., and Ferriero, D. (2014). Pharmacologic neuroprotective strategies in neonatal brain injury. Clin. Perinatol. 41, 119-131. doi: 10.1016/j.clp.2013.09.004
    • (2014) Clin. Perinatol. , vol.41 , pp. 119-131
    • Juul, S.E.1    Ferriero, D.2
  • 19
    • 80051774451 scopus 로고    scopus 로고
    • Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia-ischemia in newborn pigs
    • Lafuente, H., Alvarez, F. J., Pazos, M. R., Alvarez, A., Rey, M. C., Mielgo, V., et al. (2011). Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia-ischemia in newborn pigs. Pediatr. Res. 70, 272-277. doi: 10.1038/pr.2011.497
    • (2011) Pediatr. Res. , vol.70 , pp. 272-277
    • Lafuente, H.1    Alvarez, F.J.2    Pazos, M.R.3    Alvarez, A.4    Rey, M.C.5    Mielgo, V.6
  • 20
    • 38849108689 scopus 로고    scopus 로고
    • Rapid NMDA receptor phosphorylation and oxidative stress precede striatal neurodegeneration after hypoxic ischemia in newborn piglets and are attenuated with hypothermia
    • Mueller-Burke, D., Koehler, R. C., and Martin, L. J. (2008). Rapid NMDA receptor phosphorylation and oxidative stress precede striatal neurodegeneration after hypoxic ischemia in newborn piglets and are attenuated with hypothermia. Int. J. Dev. Neurosci. 26, 67-76. doi: 10.1016/j.ijdevneu.2007.08.015
    • (2008) Int. J. Dev. Neurosci. , vol.26 , pp. 67-76
    • Mueller-Burke, D.1    Koehler, R.C.2    Martin, L.J.3
  • 21
    • 54349125579 scopus 로고    scopus 로고
    • A piglet model for detection of hypoxic-ischemic brain injury with magnetic resonance imaging
    • Munkeby, B. H., De Lange, C., Emblem, K. E., Bjornerud, A., Kro, G. A., Andresen, J., et al. (2008). A piglet model for detection of hypoxic-ischemic brain injury with magnetic resonance imaging. Acta Radiol. 49, 1049-1057. doi: 10.1080/02841850802334224
    • (2008) Acta Radiol. , vol.49 , pp. 1049-1057
    • Munkeby, B.H.1    De Lange, C.2    Emblem, K.E.3    Bjornerud, A.4    Kro, G.A.5    Andresen, J.6
  • 22
    • 84865681650 scopus 로고    scopus 로고
    • Early antioxidant treatment and delayed hypothermia after hypoxia-ischemia have no additive neuroprotection in newborn pigs
    • Ni, X., Yang, Z. J., Wang, B., Carter, E. L., Larson, A. C., Martin, L. J., et al. (2012). Early antioxidant treatment and delayed hypothermia after hypoxia-ischemia have no additive neuroprotection in newborn pigs. Anesth. Analg. 115, 627-637. doi: 10.1213/ane.0b013e31825d3600
    • (2012) Anesth. Analg. , vol.115 , pp. 627-637
    • Ni, X.1    Yang, Z.J.2    Wang, B.3    Carter, E.L.4    Larson, A.C.5    Martin, L.J.6
  • 23
    • 67349091434 scopus 로고    scopus 로고
    • Proteomic identification of carbonylated proteins in the monkey hippocampus alter ischemia-reperfusion
    • Oikawa, S., Yamada, T., Minohata, T., Kobayashi, H., Furukawa, A., Tada-Oikawa, S., et al. (2009). Proteomic identification of carbonylated proteins in the monkey hippocampus alter ischemia-reperfusion. Free Rad. Biol. Med. 46, 1472-1477. doi: 10.1016/j.freeradbiomed.2009.02.029
    • (2009) Free Rad. Biol. Med. , vol.46 , pp. 1472-1477
    • Oikawa, S.1    Yamada, T.2    Minohata, T.3    Kobayashi, H.4    Furukawa, A.5    Tada-Oikawa, S.6
  • 24
    • 0345802708 scopus 로고    scopus 로고
    • Effects of dopamine infusion on cerebral blood flow, brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet
    • Park, W. S., Chang, Y. S., Shim, J. W., Kim, M. J., Ko, S. Y., Kim, S. S., et al. (2003). Effects of dopamine infusion on cerebral blood flow, brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet. J. Korean Med. Sci. 18, 869-875. doi: 10.3346/jkms.2003.18.6.869
    • (2003) J. Korean Med. Sci. , vol.18 , pp. 869-875
    • Park, W.S.1    Chang, Y.S.2    Shim, J.W.3    Kim, M.J.4    Ko, S.Y.5    Kim, S.S.6
  • 25
    • 84875097824 scopus 로고    scopus 로고
    • Therapeutic hypothermia for neonatal encephalopathy in low- and middle-income countries: a systematic review and meta-analysis
    • Pauliah, S. S., Shankaran, S., Wade, A., Cady, E. B., and Thayyil, S. (2013). Therapeutic hypothermia for neonatal encephalopathy in low- and middle-income countries: a systematic review and meta-analysis. PLoS ONE 8:e58834. doi: 10.1371/journal.pone.0058834
    • (2013) PLoS ONE , vol.8
    • Pauliah, S.S.1    Shankaran, S.2    Wade, A.3    Cady, E.B.4    Thayyil, S.5
  • 26
    • 84864439799 scopus 로고    scopus 로고
    • Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function
    • Pazos, M. R., Cinquina, V., Gómez, A., Layunta, R., Santos, M., Fernández-Ruiz, J., et al. (2012). Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function. Neuropharmacol 63, 776-783. doi: 10.1016/j.neuropharm.2012.05.034
    • (2012) Neuropharmacol , vol.63 , pp. 776-783
    • Pazos, M.R.1    Cinquina, V.2    Gómez, A.3    Layunta, R.4    Santos, M.5    Fernández-Ruiz, J.6
  • 27
    • 84878128163 scopus 로고    scopus 로고
    • Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: role of 5TH1A and CB2 receptors
    • Pazos, M. R., Mohammed, N., Lafuente, H., Santos, M., Martínez-Pinilla, E., Moreno, E., et al. (2013). Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: role of 5TH1A and CB2 receptors. Neuropharmacol 71, 282-291. doi: 10.1016/j.neuropharm.2013.03.027
    • (2013) Neuropharmacol , vol.71 , pp. 282-291
    • Pazos, M.R.1    Mohammed, N.2    Lafuente, H.3    Santos, M.4    Martínez-Pinilla, E.5    Moreno, E.6
  • 28
    • 12444257000 scopus 로고    scopus 로고
    • Effects of allopurinol and deferoxamine on reperfusion injury of the brain in newborn piglets after neonatal hypoxia-ischemia
    • Peeters-Scholte, C., Braun, K., Koster, J., Kops, N., Blomgren, K., Buonocore, G., et al. (2003). Effects of allopurinol and deferoxamine on reperfusion injury of the brain in newborn piglets after neonatal hypoxia-ischemia. Pediatr. Res. 54, 516-522. doi: 10.1203/01.PDR.0000081297.53793.C6
    • (2003) Pediatr. Res. , vol.54 , pp. 516-522
    • Peeters-Scholte, C.1    Braun, K.2    Koster, J.3    Kops, N.4    Blomgren, K.5    Buonocore, G.6
  • 29
    • 84873380508 scopus 로고    scopus 로고
    • Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model
    • Robertson, N. J., Faulkner, S., Fleiss, B., Bainbridge, A., Andorka, C., Price, D., et al. (2013). Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model. Brain 36, 90-105. doi: 10.1093/brain/aws285
    • (2013) Brain , vol.36 , pp. 90-105
    • Robertson, N.J.1    Faulkner, S.2    Fleiss, B.3    Bainbridge, A.4    Andorka, C.5    Price, D.6
  • 30
    • 84962279458 scopus 로고    scopus 로고
    • Twenty-four hours hypothermia has temporary efficacy in reducing brain infarction and inflammation in aged rats
    • Sandu, R. E., Buga, A. M., Balseanu, A. T., Moldovan, M., and Popa-Wagner, A. (2016). Twenty-four hours hypothermia has temporary efficacy in reducing brain infarction and inflammation in aged rats. Neurobiol. Aging 38, 127-140. doi: 10.1016/j.neurobiolaging.2015.11.006
    • (2016) Neurobiol. Aging , vol.38 , pp. 127-140
    • Sandu, R.E.1    Buga, A.M.2    Balseanu, A.T.3    Moldovan, M.4    Popa-Wagner, A.5
  • 31
    • 34548556073 scopus 로고    scopus 로고
    • Hypothermia suppresses inflammation via ERK signaling pathway in stimulated microglial cells
    • Schmitt, K. R., Diestel, A., Lehnardt, S., Schwartlander, R., Lange, P. E., Berger, F., et al. (2007). Hypothermia suppresses inflammation via ERK signaling pathway in stimulated microglial cells. J. Neuroimmunol. 189, 7-16. doi: 10.1016/j.jneuroim.2007.06.010
    • (2007) J. Neuroimmunol. , vol.189 , pp. 7-16
    • Schmitt, K.R.1    Diestel, A.2    Lehnardt, S.3    Schwartlander, R.4    Lange, P.E.5    Berger, F.6
  • 32
    • 26244462973 scopus 로고    scopus 로고
    • Neuroprotective effects of topiramate after hypoxia-ischemia in newborn piglets
    • Schubert, S., Brandl, U., Brodhun, M., Ulrich, C., Spaltmann, J., Fiedler, N., et al. (2005). Neuroprotective effects of topiramate after hypoxia-ischemia in newborn piglets. Brain Res. 1058, 129-136. doi: 10.1016/j.brainres.2005.07.061
    • (2005) Brain Res. , vol.1058 , pp. 129-136
    • Schubert, S.1    Brandl, U.2    Brodhun, M.3    Ulrich, C.4    Spaltmann, J.5    Fiedler, N.6
  • 33
    • 0030785570 scopus 로고    scopus 로고
    • Post-hypoxic hypothermia reduces cerebrocortical release of NO and excitotoxins
    • Thoresen, M., Satas, S., Puka-Sundvall, M., Whitelaw, A., Hallström, A., Loberg, E. M., et al. (1997). Post-hypoxic hypothermia reduces cerebrocortical release of NO and excitotoxins. Neuroreport 8, 3359-3362. doi: 10.1097/00001756-199710200-00033
    • (1997) Neuroreport , vol.8 , pp. 3359-3362
    • Thoresen, M.1    Satas, S.2    Puka-Sundvall, M.3    Whitelaw, A.4    Hallström, A.5    Loberg, E.M.6
  • 34


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