Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function

Neuropharmacology

Volumn 63, Issue 5, 2012, Pages 776-783

  Pazos, M R ^a   Cinquina, V ^f   Gomez A ^a   Layunta, R ^a   Santos, M ^a   Fernandez Ruiz J ^c,d,e   Martínez Orgado, José ^a,b  

^a Foundation for Biomedical Research   (Spain)

^b HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^e INSTITUTO RAMÓN Y CAJAL DE INVESTIGACIÓN SANITARIA IRYCIS   (Spain)

^f UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Cannabidiol; Follow up; Neuroprotection; Newborn; Rats

Indexed keywords

CANNABIDIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; COGNITION; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG EFFECT; EXCITOTOXICITY; FEMALE; HISTOPATHOLOGY; HYPOXIC ISCHEMIC ENCEPHALOPATHY; INFLAMMATION; MALE; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE;

ANIMALS; ANIMALS, NEWBORN; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BEHAVIOR, ANIMAL; CANNABIDIOL; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; FEMALE; HYPOXIA-ISCHEMIA, BRAIN; MALE; MOTOR ACTIVITY; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PSYCHOMOTOR DISORDERS; RANDOM ALLOCATION; RATS; RATS, WISTAR; REPERFUSION INJURY; TIME FACTORS;

EID: 84864439799     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.05.034     Document Type: Article

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