메뉴 건너뛰기




Volumn 31, Issue 1, 2017, Pages 186-194

Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; KINETOPLAST DNA; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84982871882     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2016.180     Document Type: Article
Times cited : (190)

References (51)
  • 1
    • 84896335556 scopus 로고    scopus 로고
    • Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
    • Davila ML, Riviere I, Wang X, Bartido S, Park J, Curran K et al. Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci Transl Med 2014; 6: 224-225
    • (2014) Sci Transl Med , vol.6 , pp. 224-225
    • Davila, M.L.1    Riviere, I.2    Wang, X.3    Bartido, S.4    Park, J.5    Curran, K.6
  • 3
    • 84923118622 scopus 로고    scopus 로고
    • Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor
    • Kochenderfer JN, Dudley ME, Kassim SH, Somerville RP, Carpenter RO, Stetler-Stevenson M et al. Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor. J Clin Oncol 2015; 33: 540-549
    • (2015) J Clin Oncol , vol.33 , pp. 540-549
    • Kochenderfer, J.N.1    Dudley, M.E.2    Kassim, S.H.3    Somerville, R.P.4    Carpenter, R.O.5    Stetler-Stevenson, M.6
  • 4
    • 84879545641 scopus 로고    scopus 로고
    • Comparison of lentiviral and sleeping beauty mediated alphabeta T cell receptor gene transfer
    • Field AC, Vink C, Gabriel R, Al-Subki R, Schmidt M, Goulden N et al. Comparison of lentiviral and sleeping beauty mediated alphabeta T cell receptor gene transfer. PloS One 2013; 8: e68201
    • (2013) PloS One , vol.8 , pp. e68201
    • Field, A.C.1    Vink, C.2    Gabriel, R.3    Al-Subki, R.4    Schmidt, M.5    Goulden, N.6
  • 6
    • 67349132909 scopus 로고    scopus 로고
    • Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells
    • Wang GP, Levine BL, Binder GK, Berry CC, Malani N, McGarrity G et al. Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells. Mol Ther 2009; 17: 844-850
    • (2009) Mol Ther , vol.17 , pp. 844-850
    • Wang, G.P.1    Levine, B.L.2    Binder, G.K.3    Berry, C.C.4    Malani, N.5    McGarrity, G.6
  • 7
    • 77956668327 scopus 로고    scopus 로고
    • Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges
    • Izsvak Z, Hackett PB, Cooper LJ, Ivics Z. Translating Sleeping Beauty transposition into cellular therapies: victories and challenges. BioEssays 2010; 32: 756-767
    • (2010) BioEssays , vol.32 , pp. 756-767
    • Izsvak, Z.1    Hackett, P.B.2    Cooper, L.J.3    Ivics, Z.4
  • 8
    • 84855679243 scopus 로고    scopus 로고
    • The Sleeping Beauty transposon system for clinical applications
    • Swierczek M, Izsvak Z, Ivics Z. The Sleeping Beauty transposon system for clinical applications. Exp Opin Biol Ther 2012; 12: 139-153
    • (2012) Exp Opin Biol Ther , vol.12 , pp. 139-153
    • Swierczek, M.1    Izsvak, Z.2    Ivics, Z.3
  • 9
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of sleeping beauty, a Tc1-like transposon from fish, and its transposition in human cells
    • Ivics Z, Hackett PB, Plasterk RH, Izsvak Z. Molecular reconstruction of sleeping beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 1997; 91: 501-510
    • (1997) Cell , vol.91 , pp. 501-510
    • Ivics, Z.1    Hackett, P.B.2    Plasterk, R.H.3    Izsvak, Z.4
  • 10
    • 67349250885 scopus 로고    scopus 로고
    • Molecular evolution of a novel hyperactive sleeping beauty transposase enables robust stable gene transfer in vertebrates
    • Mates L, Chuah MK, Belay E, Jerchow B, Manoj N, Acosta-Sanchez A et al. Molecular evolution of a novel hyperactive sleeping beauty transposase enables robust stable gene transfer in vertebrates. Nat Genet 2009; 41: 753-761
    • (2009) Nat Genet , vol.41 , pp. 753-761
    • Mates, L.1    Chuah, M.K.2    Belay, E.3    Jerchow, B.4    Manoj, N.5    Acosta-Sanchez, A.6
  • 11
    • 69249221308 scopus 로고    scopus 로고
    • Efficient nonviral sleeping beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity
    • Peng PD, Cohen CJ, Yang S, Hsu C, Jones S, Zhao Y et al. Efficient nonviral sleeping beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity. Gene Ther 2009; 16: 1042-1049
    • (2009) Gene Ther , vol.16 , pp. 1042-1049
    • Peng, P.D.1    Cohen, C.J.2    Yang, S.3    Hsu, C.4    Jones, S.5    Zhao, Y.6
  • 12
    • 39849086801 scopus 로고    scopus 로고
    • Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies
    • Huang X, Guo H, Kang J, Choi S, Zhou TC, Tammana S et al. Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies. Mol Ther 2008; 16: 580-589
    • (2008) Mol Ther , vol.16 , pp. 580-589
    • Huang, X.1    Guo, H.2    Kang, J.3    Choi, S.4    Zhou, T.C.5    Tammana, S.6
  • 13
    • 80052575522 scopus 로고    scopus 로고
    • The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor
    • Jin Z, Maiti S, Huls H, Singh H, Olivares S, Mates L et al. The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor. Gene Ther 2011; 18: 849-856
    • (2011) Gene Ther , vol.18 , pp. 849-856
    • Jin, Z.1    Maiti, S.2    Huls, H.3    Singh, H.4    Olivares, S.5    Mates, L.6
  • 14
    • 42349088534 scopus 로고    scopus 로고
    • Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system
    • Singh H, Manuri PR, Olivares S, Dara N, Dawson MJ, Huls H et al. Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system. Cancer Res 2008; 68: 2961-2971
    • (2008) Cancer Res , vol.68 , pp. 2961-2971
    • Singh, H.1    Manuri, P.R.2    Olivares, S.3    Dara, N.4    Dawson, M.J.5    Huls, H.6
  • 15
    • 84878547375 scopus 로고    scopus 로고
    • Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells
    • Singh H, Figliola MJ, Dawson MJ, Olivares S, Zhang L, Yang G et al. Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells. PloS One 2013; 8: e64138
    • (2013) PloS One , vol.8 , pp. e64138
    • Singh, H.1    Figliola, M.J.2    Dawson, M.J.3    Olivares, S.4    Zhang, L.5    Yang, G.6
  • 16
    • 84890209444 scopus 로고    scopus 로고
    • A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19
    • Singh H, Huls H, Kebriaei P, Cooper LJ. A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19. Immunol Rev 2014; 257: 181-190
    • (2014) Immunol Rev , vol.257 , pp. 181-190
    • Singh, H.1    Huls, H.2    Kebriaei, P.3    Cooper, L.J.4
  • 17
    • 84925607772 scopus 로고    scopus 로고
    • Adoptive cellular therapy: A race to the finish line
    • June CH, Riddell SR, Schumacher TN. Adoptive cellular therapy: a race to the finish line. Sci Transl Med 2015; 7: 280ps287
    • (2015) Sci Transl Med , vol.7 , pp. 280ps287
    • June, C.H.1    Riddell, S.R.2    Schumacher, T.N.3
  • 20
    • 0041315884 scopus 로고    scopus 로고
    • Vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
    • Minicircle DNA
    • Chen ZY, He CY, Ehrhardt A, Kay MA, Minicircle DNA. vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. Mol Ther 2003; 8: 495-500
    • (2003) Mol Ther , vol.8 , pp. 495-500
    • Chen, Z.Y.1    He, C.Y.2    Ehrhardt, A.3    Kay, M.A.4
  • 21
    • 78650028269 scopus 로고    scopus 로고
    • A robust system for production of minicircle DNA vectors
    • Kay MA, He CY, Chen ZY. A robust system for production of minicircle DNA vectors. Nat Biotechnol 2010; 28: 1287-1289
    • (2010) Nat Biotechnol , vol.28 , pp. 1287-1289
    • Kay, M.A.1    He, C.Y.2    Chen, Z.Y.3
  • 22
    • 58149193835 scopus 로고    scopus 로고
    • Minicircle-DNA production by site specific recombination and protein-DNA interaction chromatography
    • Mayrhofer P, Blaesen M, Schleef M, Jechlinger W. Minicircle-DNA production by site specific recombination and protein-DNA interaction chromatography. J Gene Med 2008; 10: 1253-1269
    • (2008) J Gene Med , vol.10 , pp. 1253-1269
    • Mayrhofer, P.1    Blaesen, M.2    Schleef, M.3    Jechlinger, W.4
  • 23
    • 84871977997 scopus 로고    scopus 로고
    • Electrotransfer for efficient tissue-targeted gene delivery
    • Minicircle DNA
    • Chabot S, Orio J, Schmeer M, Schleef M, Golzio M, Teissie J, Minicircle DNA. Electrotransfer for efficient tissue-targeted gene delivery. Gene Ther 2013; 20: 62-68
    • (2013) Gene Ther , vol.20 , pp. 62-68
    • Chabot, S.1    Orio, J.2    Schmeer, M.3    Schleef, M.4    Golzio, M.5    Teissie, J.6
  • 26
    • 0036317929 scopus 로고    scopus 로고
    • Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon
    • Cui Z, Geurts AM, Liu G, Kaufman CD, Hackett PB. Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon. J Mol Biol 2002; 318: 1221-1235
    • (2002) J Mol Biol , vol.318 , pp. 1221-1235
    • Cui, Z.1    Geurts, A.M.2    Liu, G.3    Kaufman, C.D.4    Hackett, P.B.5
  • 27
    • 84953344459 scopus 로고    scopus 로고
    • The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity
    • Hudecek M, Sommermeyer D, Kosasih PL, Silva-Benedict A, Liu L, Rader C et al. The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity. Cancer Immunol Res 2015; 3: 125-135
    • (2015) Cancer Immunol Res , vol.3 , pp. 125-135
    • Hudecek, M.1    Sommermeyer, D.2    Kosasih, P.L.3    Silva-Benedict, A.4    Liu, L.5    Rader, C.6
  • 28
    • 80051589534 scopus 로고    scopus 로고
    • A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells
    • Wang X, Chang WC, Wong CW, Colcher D, Sherman M, Ostberg JR et al. A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells. Blood 2011; 118: 1255-1263
    • (2011) Blood , vol.118 , pp. 1255-1263
    • Wang, X.1    Chang, W.C.2    Wong, C.W.3    Colcher, D.4    Sherman, M.5    Ostberg, J.R.6
  • 29
    • 84879480191 scopus 로고    scopus 로고
    • Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells
    • Hudecek M, Lupo-Stanghellini MT, Kosasih PL, Sommermeyer D, Jensen MC, Rader C et al. Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells. Clin Cancer Res 2013; 19: 3153-3164
    • (2013) Clin Cancer Res , vol.19 , pp. 3153-3164
    • Hudecek, M.1    Lupo-Stanghellini, M.T.2    Kosasih, P.L.3    Sommermeyer, D.4    Jensen, M.C.5    Rader, C.6
  • 30
    • 78649461928 scopus 로고    scopus 로고
    • The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor
    • Hudecek M, Schmitt TM, Baskar S, Lupo-Stanghellini MT, Nishida T, Yamamoto TN et al. The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor. Blood 2010; 116: 4532-4541
    • (2010) Blood , vol.116 , pp. 4532-4541
    • Hudecek, M.1    Schmitt, T.M.2    Baskar, S.3    Lupo-Stanghellini, M.T.4    Nishida, T.5    Yamamoto, T.N.6
  • 32
    • 84959328185 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells derived from defined CD8 and CD4 subsets confer superior antitumor reactivity in vivo
    • Sommermeyer D, Hudecek M, Kosasih PL, Gogishvili T, Maloney DG, Turtle CJ et al. Chimeric antigen receptor-modified T cells derived from defined CD8 and CD4 subsets confer superior antitumor reactivity in vivo. Leukemia 2015; 30: 492-500
    • (2015) Leukemia , vol.30 , pp. 492-500
    • Sommermeyer, D.1    Hudecek, M.2    Kosasih, P.L.3    Gogishvili, T.4    Maloney, D.G.5    Turtle, C.J.6
  • 33
    • 84962213143 scopus 로고    scopus 로고
    • Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells
    • Frigault MJ, Lee J, Basil MC, Carpenito C, Motohashi S, Scholler J et al. Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells. Cancer Immunol Res 2015; 3: 356-367
    • (2015) Cancer Immunol Res , vol.3 , pp. 356-367
    • Frigault, M.J.1    Lee, J.2    Basil, M.C.3    Carpenito, C.4    Motohashi, S.5    Scholler, J.6
  • 34
    • 1342290203 scopus 로고    scopus 로고
    • Development of hyperactive sleeping beauty transposon vectors by mutational analysis
    • Zayed H, Izsvak Z, Walisko O, Ivics Z. Development of hyperactive sleeping beauty transposon vectors by mutational analysis. Mol Ther 2004; 9: 292-304
    • (2004) Mol Ther , vol.9 , pp. 292-304
    • Zayed, H.1    Izsvak, Z.2    Walisko, O.3    Ivics, Z.4
  • 35
    • 0036404918 scopus 로고    scopus 로고
    • Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements
    • Vigdal TJ, Kaufman CD, Izsvak Z, Voytas DF, Ivics Z. Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements. J Mol Biol 2002; 323: 441-452
    • (2002) J Mol Biol , vol.323 , pp. 441-452
    • Vigdal, T.J.1    Kaufman, C.D.2    Izsvak, Z.3    Voytas, D.F.4    Ivics, Z.5
  • 36
    • 39749145198 scopus 로고    scopus 로고
    • Dynamic regulation of nucleosome positioning in the human genome
    • Schones DE, Cui K, Cuddapah S, Roh TY, Barski A, Wang Z et al. Dynamic regulation of nucleosome positioning in the human genome. Cell 2008; 132: 887-898
    • (2008) Cell , vol.132 , pp. 887-898
    • Schones, D.E.1    Cui, K.2    Cuddapah, S.3    Roh, T.Y.4    Barski, A.5    Wang, Z.6
  • 37
    • 78651337233 scopus 로고    scopus 로고
    • Genomic safe harbors permit high beta-globin transgene expression in thalassemia induced pluripotent stem cells
    • Papapetrou EP, Lee G, Malani N, Setty M, Riviere I, Tirunagari LM et al. Genomic safe harbors permit high beta-globin transgene expression in thalassemia induced pluripotent stem cells. Nat Biotechnol 2011; 29: 73-78
    • (2011) Nat Biotechnol , vol.29 , pp. 73-78
    • Papapetrou, E.P.1    Lee, G.2    Malani, N.3    Setty, M.4    Riviere, I.5    Tirunagari, L.M.6
  • 38
    • 84655170273 scopus 로고    scopus 로고
    • Safe harbours for the integration of new DNA in the human genome
    • Sadelain M, Papapetrou EP, Bushman FD. Safe harbours for the integration of new DNA in the human genome. Nat Revi Cancer 2012; 12: 51-58
    • (2012) Nat Revi Cancer , vol.12 , pp. 51-58
    • Sadelain, M.1    Papapetrou, E.P.2    Bushman, F.D.3
  • 39
    • 84960192213 scopus 로고    scopus 로고
    • Gene insertion into genomic safe harbors for human gene therapy
    • Papapetrou EP, Schambach A. Gene insertion into genomic safe harbors for human gene therapy. Mol Ther 2016; 24: 678-684
    • (2016) Mol Ther , vol.24 , pp. 678-684
    • Papapetrou, E.P.1    Schambach, A.2
  • 40
    • 0034623009 scopus 로고    scopus 로고
    • Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates
    • Izsvak Z, Ivics Z, Plasterk RH. Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates. J Mol Biol 2000; 302: 93-102
    • (2000) J Mol Biol , vol.302 , pp. 93-102
    • Izsvak, Z.1    Ivics, Z.2    Plasterk, R.H.3
  • 43
    • 32944463921 scopus 로고    scopus 로고
    • RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues
    • Wilber A, Frandsen JL, Geurts JL, Largaespada DA, Hackett PB, McIvor RS. RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues. Mol Ther 2006; 13: 625-630
    • (2006) Mol Ther , vol.13 , pp. 625-630
    • Wilber, A.1    Frandsen, J.L.2    Geurts, J.L.3    Largaespada, D.A.4    Hackett, P.B.5    McIvor, R.S.6
  • 44
  • 45
    • 84901361283 scopus 로고    scopus 로고
    • Chromatin landscapes of retroviral and transposon integration profiles
    • de Jong J, Akhtar W, Badhai J, Rust AG, Rad R, Hilkens J et al. Chromatin landscapes of retroviral and transposon integration profiles. PLoS Genet 2014; 10: e1004250
    • (2014) PLoS Genet , vol.10 , pp. e1004250
    • De Jong, J.1    Akhtar, W.2    Badhai, J.3    Rust, A.G.4    Rad, R.5    Hilkens, J.6
  • 47
    • 77957579849 scopus 로고    scopus 로고
    • Gene transfer efficiency and genome-wide integration profiling of Sleeping Beauty, Tol2, and piggyBac transposons in human primary T cells
    • Huang X, Guo H, Tammana S, Jung YC, Mellgren E, Bassi P et al. Gene transfer efficiency and genome-wide integration profiling of Sleeping Beauty, Tol2, and piggyBac transposons in human primary T cells. Mol Ther 2010; 18: 1803-1813
    • (2010) Mol Ther , vol.18 , pp. 1803-1813
    • Huang, X.1    Guo, H.2    Tammana, S.3    Jung, Y.C.4    Mellgren, E.5    Bassi, P.6
  • 48
    • 84904115855 scopus 로고    scopus 로고
    • HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
    • Maldarelli F, Wu X, Su L, Simonetti FR, Shao W, Hill S et al. HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science 2014; 345: 179-183
    • (2014) Science , vol.345 , pp. 179-183
    • Maldarelli, F.1    Wu, X.2    Su, L.3    Simonetti, F.R.4    Shao, W.5    Hill, S.6
  • 49
    • 84866978628 scopus 로고    scopus 로고
    • Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains
    • Voigt K, Gogol-Doring A, Miskey C, Chen W, Cathomen T, Izsvak Z et al. Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains. Mol Ther 2012; 20: 1852-1862
    • (2012) Mol Ther , vol.20 , pp. 1852-1862
    • Voigt, K.1    Gogol-Doring, A.2    Miskey, C.3    Chen, W.4    Cathomen, T.5    Izsvak, Z.6
  • 51
    • 84897557033 scopus 로고    scopus 로고
    • Adoptive therapy with chimeric antigen receptor-modified T cells of defined subset composition
    • Riddell SR, Sommermeyer D, Berger C, Liu LS, Balakrishnan A, Salter A et al. Adoptive therapy with chimeric antigen receptor-modified T cells of defined subset composition. Cancer J 2014; 20: 141-144.
    • (2014) Cancer J , vol.20 , pp. 141-144
    • Riddell, S.R.1    Sommermeyer, D.2    Berger, C.3    Liu, L.S.4    Balakrishnan, A.5    Salter, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.