Functional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies for host adaptation and persistence

BMC Genomics

Volumn 17, Issue 1, 2016, Pages

  Miranda CasoLuengo, Aleksandra A ^a   Staunton, Patrick M ^a   Dinan, Adam M ^a   Lohan, Amanda J ^b   Loftus, Brendan J ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Antibiotic; Cystic fibrosis; Integrated map; Mycobacterium abscessus; WhiB7

Indexed keywords

GLYOXYLIC ACID; TRANSCRIPTOME; ANTIINFECTIVE AGENT; BACTERIAL RNA; FATTY ACID; IRON; ISOPROTEIN; SIDEROPHORE;

ACTIVE TRANSPORT; AMINO ACID METABOLISM; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BIOFILM; FATTY ACID METABOLISM; FUNCTIONAL GENOMICS; HYPOXIA; LIQUID CHROMATOGRAPHY; LUNG FIBROSIS; MASS SPECTROMETRY; MOLECULAR EVOLUTION; MYCOBACTERIUM ABSCESSUS; NONHUMAN; OPEN READING FRAME; PROTEOMICS; PSEUDOMONAS AERUGINOSA; RIBOSOME; RNA SEQUENCE; RNA TRANSLATION; SPUTUM; TRANSCRIPTOMICS; ADAPTATION; BIOSYNTHESIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; HOST PATHOGEN INTERACTION; METABOLISM; MYCOBACTERIUM; PHYSIOLOGICAL STRESS;

ADAPTATION, BIOLOGICAL; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; EVOLUTION, MOLECULAR; FATTY ACIDS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOST-PATHOGEN INTERACTIONS; HYPOXIA; IRON; MYCOBACTERIUM; OPEN READING FRAMES; PROTEIN ISOFORMS; RNA, BACTERIAL; SIDEROPHORES; STRESS, PHYSIOLOGICAL; TRANSCRIPTOME;

EID: 84982868458     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-016-2868-y     Document Type: Article

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