The vapA co-expressed virulence plasmid gene vcgB (orf10) of the intracellular actinomycete Rhodococcus equi

Microbiology

Volumn 157, Issue 8, 2011, Pages 2357-2368

  Miranda Casoluengo, Raúl ^a   Miranda Casoluengo, Aleksandra A ^a   O'Connell, Enda P ^a,d   Fahey, Ruth J ^a,e   Boland, Clara A ^a,f   Vázquez Boland, Jose A ^b,c   Meijer, Wim G ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF LEÓN   (Spain)

^d NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^e Cornell University ^*  (United States)

^f Forensic Science Laboratory Dulin Ireland   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; UNCLASSIFIED DRUG; VAPA PROTEIN; VAPB PROTEIN; VCGB PROTEIN; VCGC PROTEIN; VIRULENCE FACTOR;

ACTINOBACTERIA; ANIMAL CELL; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; GENE EXPRESSION; HIGH TEMPERATURE; INTRACELLULAR BACTERIUM; MYCOBACTERIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OPERON; PH; PHAGOCYTOSIS; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; RECEPTOR UPREGULATION; RHODOCOCCUS EQUI; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BACTERIAL PROTEINS; CELL LINE; CONSERVED SEQUENCE; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GENOMIC ISLANDS; HYDROGEN-ION CONCENTRATION; KINETICS; MACROPHAGES; MICE; MYCOBACTERIUM; OPERON; PHAGOCYTOSIS; PLASMIDS; PROMOTER REGIONS, GENETIC; RHODOCOCCUS EQUI; RNA STABILITY; RNA, BACTERIAL; RNA, MESSENGER; TEMPERATURE; TIME FACTORS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC; VIRULENCE; VIRULENCE FACTORS;

CORYNEBACTERINEAE; RHODOCOCCUS EQUI; SUS;

EID: 79961069227     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.049759-0     Document Type: Article

References (49)

1. Butcher, P. D., Mangan, J. A. & Monahan, I. M. (1998). Intracellular gene expression. Analysis of RNA from mycobacteria in macrophages using RT-PCR. Methods Mol Biol 101, 285-306.
2. Buttner, M. J., Chater, K. F. & Bibb, M. J. (1990). Cloning, disruption, and transcriptional analysis of three RNA polymerase sigma factor genes of Streptomyces coelicolor A3(2). J Bacteriol 172, 3367-3378.
3. Byrne, B. A., Prescott, J. F., Palmer, G. H., Takai, S., Nicholson, V. M., Alperin, D. C. & Hines, S. A. (2001). Virulence plasmid of Rhodococcus equi contains inducible gene family encoding secreted proteins. Infect Immun 69, 650-656.
4. Byrne, G. A., Russell, D. A., Chen, X. & Meijer, W. G. (2007). Transcriptional regulation of the virR operon of the intracellular pathogen Rhodococcus equi. J Bacteriol 189, 5082-5089.
5. Byrne, G. A., Boland, C. A., O'Connell, E. P. & Meijer, W. G. (2008). Differential mRNA stability of the vapAICD operon of the facultative intracellular pathogen Rhodococcus equi. FEMS Microbiol Lett 280, 89-94.
6. Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S. & other authors (1998). Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393, 537-544.
7. De La Peña-Moctezuma, A., Prescott, J. F. & Goodfellow, M. (1996). Attempts to find phenotypic markers of the virulence plasmid of Rhodococcus equi. Can J Vet Res 60, 29-33.
8. Demangel, C., Stinear, T. P. & Cole, S. T. (2009). Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcer-ans. Nat Rev Microbiol 7, 50-60.
9. Devulder, G., Pérouse de Montclos, M. & Flandrois, J. P. (2005). A multigene approach to phylogenetic analysis using the genus Mycobacterium as a model. Int J Syst Evol Microbiol 55, 293-302.
10. Felsenstein, J. (1989). PHYLIP - phylogeny inference package (version 3.2). Cladistics 5, 164-166.
11. Fernandez-Mora, E., Polidori, M., Lührmann, A., Schaible, U. E., & Haas, A. (2005). Maturation of Rhodococcus equi-containing vacuoles is arrested after completion of the early endosome stage. Traffic 6, 635-653.
12. Fleischmann, R. D., Alland, D., Eisen, J. A., Carpenter, L., White, O., Peterson, J., DeBoy, R., Dodson, R., Gwinn, M. & other authors (2002). Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains. J Bacteriol 184, 5479-5490.
13. Giguère, S., Hondalus, M. K., Yager, J. A., Darrah, P., Mosser, D. M. & Prescott, J. F. (1999). Role of the 85-kilobase plasmid and plasmid-encoded virulence-associated protein A in intracellular survival and virulence of Rhodococcus equi. Infect Immun 67, 3548-3557.
14. Hondalus, M. K. & Mosser, D. M. (1994). Survival and replication of Rhodococcus equi in macrophages. Infect Immun 62, 4167-4175.
15. Hondalus, M. K., Diamond, M. S., Rosenthal, L. A., Springer, T. A. & Mosser, D. M. (1993). The intracellular bacterium Rhodococcus equi requires Mac-1 to bind to mammalian cells. Infect Immun 61, 2919-2929.
16. S controls multiple pathways associated with intracellular multiplication of Legionella pneumophila. J Bacteriol 191, 2461-2473.
17. Hughes, K. L. & Sulaiman, I. (1987). The ecology of Rhodococcus equi and physicochemical influences on growth. Vet Microbiol 14, 241-250.
18. Iriarte, M., Stainier, I. & Cornelis, G. R. (1995). The rpoS gene from Yersinia enterocolitica and its influence on expression of virulence factors. Infect Immun 63, 1840-1847.
19. Jain, S., Bloom, B. R. & Hondalus, M. K. (2003). Deletion of vapA encoding virulence associated protein A attenuates the intracellular actinomycete Rhodococcus equi. Mol Microbiol 50, 115-128.
20. Jones, D. T., Taylor, W. R. & Thornton, J. M. (1992). The rapid generation of mutation data matrices from protein sequences. Comput Appl Biosci 8, 275-282.
21. Kang, J. G., Hahn, M. Y., Ishihama, A. & Roe, J. H. (1997). Identification of sigma factors for growth phase-related promoter selectivity of RNA polymerases from Streptomyces coelicolor A3(2). Nucleic Acids Res 25, 2566-2573.
22. Kelly, B. G., Wall, D. M., Boland, C. A. & Meijer, W. G. (2002). Isocitrate lyase of the facultative intracellular pathogen Rhodococcus equi. Microbiology 148, 793-798.
23. Klinkert, B. & Narberhaus, F. (2009). Microbial thermosensors. Cell Mol Life Sci 66, 2661-2676.
24. Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M., Wilm, A. & other authors (2007). CLUSTAL_W and CLUSTAL_X version 2.0. Bioinformatics 23, 2947-2948.
25. Letek, M., Ocampo-Sosa, A. A., Sanders, M., Fogarty, U., Buckley, T., Leadon, D. P., González, P., Scortti, M., Meijer, W. G. & other authors (2008). Evolution of the Rhodococcus equi vap pathogenicity island seen through comparison of host-associated vapA and vapB virulence plasmids. J Bacteriol 190, 5797-5805.
26. Letek, M., González, P., Macarthur, I., Rodríguez, H., Freeman, T. C., Valero-Rello, A., Blanco, M., Buckley, T., Cherevach, I. & other authors (2010). The genome of a pathogenic Rhodococcus: cooptive virulence underpinned by key gene acquisitions. PLoS Genet 6, e1001145.
27. Li, L., Bannantine, J. P., Zhang, Q., Amonsin, A., May, B. J., Alt, D., Banerji, N., Kanjilal, S. & Kapur, V. (2005). The complete genome sequence of Mycobacterium avium subspecies paratuberculosis. Proc Natl Acad Sci USA 102, 12344-12349.
28. Lührmann, A., Mauder, N., Sydor, T., Fernandez-Mora, E., Schulze-Luehrmann, J., Takai, S. & Haas, A. (2004). Necrotic death of Rhodococcus equi-infected macrophages is regulated by virulence-associated plasmids. Infect Immun 72, 853-862.
29. Meijer, W. G. & Prescott, J. F. (2004). Rhodococcus equi. Vet Res 35, 383-396.
30. Miranda-CasoLuengo, R., Duffy, P. S., O'Connell, E. P., Graham, B. J., Mangan, M. W., Prescott, J. F. & Meijer, W. G. (2005). The iron-regulated iupABC operon is required for saprophytic growth of the intracellular pathogen Rhodococcus equi at low iron concentrations. J Bacteriol 187, 3438-3444.
31. Muscatello, G., Leadon, D. P., Klayt, M., Ocampo-Sosa, A., Lewis, D. A., Fogarty, U., Buckley, T., Gilkerson, J. R., Meijer, W. G. & Vazquez-Boland, J. A. (2007). Rhodococcus equi infection in foals: the science of 'rattles'. Equine Vet J 39, 470-478.
32. Nielsen, A. T., Dolganov, N. A., Otto, G., Miller, M. C., Wu, C. Y. & Schoolnik, G. K. (2006). RpoS controls the Vibrio cholerae mucosal escape response. PLoS Pathog 2, e109.
33. Ocampo-Sosa, A. A., Lewis, D. A., Navas, J., Quigley, F., Callejo, R., Scortti, M., Leadon, D. P., Fogarty, U. & Vázquez-Boland, J. A. (2007). Molecular epidemiology of Rhodococcus equi based on traA, vapA, and vapB virulence plasmid markers. J Infect Dis 196, 763-769.
34. Pfaffl, M. W. (2004). Quantification strategies in real-time PCR. In A-Z of Quantitative PCR, pp. 87-112. Edited by S. A. Bustin. La Jolla, CA: International University Line.
35. Platt, T. (1986). Transcription termination and the regulation of gene expression. Annu Rev Biochem 55, 339-372.
36. Polidori, M. & Haas, A. (2006). VapI, a new member of the Rhodococcus equi Vap family. Antonie van Leeuwenhoek 90, 299-304.
37. Ren, J. & Prescott, J. F. (2003). Analysis of virulence plasmid gene expression of intra-macrophage and in vitro grown Rhodococcus equi ATCC 33701. Vet Microbiol 94, 167-182.
38. Ren, J. & Prescott, J. F. (2004). The effect of mutation on Rhodococcus equi virulence plasmid gene expression and mouse virulence. Vet Microbiol 103, 219-230.
39. Ripoll, F., Pasek, S., Schenowitz, C., Dossat, C., Barbe, V., Rottman, M., Macheras, E., Heym, B., Herrmann, J. L. & other authors (2009). Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus. PLoS ONE 4, e5660.
40. Rohde, K. H., Abramovitch, R. B. & Russell, D. G. (2007). Mycobacterium tuberculosis invasion of macrophages: linking bacterial gene expression to environmental cues. Cell Host Microbe 2, 352-364.
41. Russell, D. A., Byrne, G. A., O'Connell, E. P., Boland, C. A. & Meijer, W. G. (2004). The LysR-type transcriptional regulator VirR is required for expression of the virulence gene vapA of Rhodococcus equi ATCC 33701. J Bacteriol 186, 5576-5584.
42. Sambrook, J. & Russell, D. W. (2001). Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
43. Sekine, M., Tanikawa, S., Omata, S., Saito, M., Fujisawa, T., Tsukatani, N., Tajima, T., Sekigawa, T., Kosugi, H. & other authors (2006). Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4. Environ Microbiol 8, 334-346.
44. Stinear, T. P., Seemann, T., Pidot, S., Frigui, W., Reysset, G., Garnier, T., Meurice, G., Simon, D., Bouchier, C. & other authors (2007). Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer. Genome Res 17, 192-200.
45. Stinear, T. P., Seemann, T., Harrison, P. F., Jenkin, G. A., Davies, J. K., Johnson, P. D., Abdellah, Z., Arrowsmith, C., Chillingworth, T. & other authors (2008). Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis. Genome Res 18, 729-741.
46. Takai, S., Fukunaga, N., Kamisawa, K., Imai, Y., Sasaki, Y. & Tsubaki, S. (1996). Expression of virulence-associated antigens of Rhodococcus equi is regulated by temperature and pH. Microbiol Immunol 40, 591- 594.
47. Takai, S., Hines, S. A., Sekizaki, T., Nicholson, V. M., Alperin, D. A., Osaki, M., Takamatsu, D., Nakamura, M., Suzuki, K. & other authors (2000). DNA sequence and comparison of virulence plasmids from Rhodococcus equi ATCC 33701 and 103. Infect Immun 68, 6840-6847.
48. Toyooka, K., Takai, S. & Kirikae, T. (2005). Rhodococcus equi can survive a phagolysosomal environment in macrophages by suppressing acidification of the phagolysosome. J Med Microbiol 54, 1007-1015.
49. von Bargen, K., Wohlmann, J., Taylor, G. A., Utermöhlen, O. & Haas, A. (2011). Nitric oxide-mediated intracellular growth restriction of pathogenic Rhodococcus equi can be prevented by iron. Infect Immun 79, 2098-2111.