mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells

Apoptosis

Volumn 21, Issue 10, 2016, Pages 1158-1178

  Berrak, Ozge ^a   Arisan, Elif Damla ^a   Obakan Yerlikaya, Pinar ^a   Coker Gürkan, Ajda ^a   Palavan Unsal, Narçin ^a  

^a ISTANBUL KULTUR UNIVERSITY   (Turkey)

Author keywords

Apoptosis; Autophagy; mTOR; Purvalanol; Roscovitine

Indexed keywords

ANDROGEN RECEPTOR; CASPASE 3; CASPASE 7; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN MCL 1; PURVALANOL; RAPAMYCIN; ROSCOVITINE; SMALL INTERFERING RNA; TENSIN; 6-((3-CHLORO)ANILINO)-2-(ISOPROPYL-2-HYDROXYETHYLAMINO)-9-ISOPROPYLPURINE; AR PROTEIN, HUMAN; MTOR PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; PURINE DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

APOPTOSIS; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; CELL PROLIFERATION; CELL SURVIVAL; CELL VACUOLE; CELL VIABILITY; CELL VIABILITY ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME IMMUNOASSAY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LNCAP CELL LINE; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; AUTOPHAGY; CELL CYCLE; DRUG EFFECTS; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

APOPTOSIS; AUTOPHAGY; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MALE; PROSTATIC NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PURINES; RECEPTORS, ANDROGEN; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84982792246     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-016-1275-9     Document Type: Article

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