Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner

Journal of Lipid Research

Volumn 57, Issue 8, 2016, Pages 1564-1573

  Shao, Wei ^a   Machamer, Carolyn E ^a   Espenshade, Peter J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endoplasmic reticulum; Endoplasmic reticulum to golgi transport; Sterol regulatory element binding protein; Sterol regulatory element binding protein cleavage activating protein

Indexed keywords

FATOSTATIN; MEMBRANE PROTEIN; PROTEIN INHIBITOR; SREBP CLEAVAGE ACTIVATING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; PYRIDINE DERIVATIVE; SIGNAL PEPTIDE; SREBP CLEAVAGE-ACTIVATING PROTEIN; THIAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CRISPR CAS SYSTEM; EMBRYO; ENDOPLASMIC RETICULUM; GOLGI MEMBRANE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; VESICULOVIRUS; ANIMAL; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; GOLGI COMPLEX; HAMSTER; HEK293 CELL LINE; METABOLISM; PRECLINICAL STUDY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; DRUG EVALUATION, PRECLINICAL; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; PROTEIN TRANSPORT; PYRIDINES; THIAZOLES;

EID: 84982676424     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M069583     Document Type: Article

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