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Volumn 7, Issue 33, 2016, Pages 53751-53761

Oral administration of withaferin-A inhibits carcinogenesis of prostate in TRAMP model

Author keywords

Chemoprevention; Dietary agents; Prostate cancer

Indexed keywords

BETA CATENIN; BLOOD CLOTTING FACTOR 8; CELL PROTEIN; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 4; RETIC PROTEIN; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; WITHAFERIN A; ANTINEOPLASTIC AGENT; WITHANOLIDE;

EID: 84982273207     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.10733     Document Type: Article
Times cited : (36)

References (59)
  • 1
    • 34247111243 scopus 로고    scopus 로고
    • International study into the use of intermittent hormone therapy in the treatment of carcinoma of the prostate: a meta-analysis of 1446 patients
    • Shaw GL, Wilson P, Cuzick J, Prowse DM, Goldenberg SL, Spry NA and Oliver T. International study into the use of intermittent hormone therapy in the treatment of carcinoma of the prostate: a meta-analysis of 1446 patients. BJU Int. 2007; 99:1056-1065.
    • (2007) BJU Int , vol.99 , pp. 1056-1065
    • Shaw, G.L.1    Wilson, P.2    Cuzick, J.3    Prowse, D.M.4    Goldenberg, S.L.5    Spry, N.A.6    Oliver, T.7
  • 2
    • 84905924290 scopus 로고    scopus 로고
    • The influence of prior abiraterone treatment on the clinical activity of docetaxel in men with metastatic castration-resistant prostate cancer
    • Schweizer MT, Zhou XC, Wang H, Bassi S, Carducci MA, Eisenberger MA and Antonarakis ES. The influence of prior abiraterone treatment on the clinical activity of docetaxel in men with metastatic castration-resistant prostate cancer. Eur Urol. 2014; 66:646-652.
    • (2014) Eur Urol , vol.66 , pp. 646-652
    • Schweizer, M.T.1    Zhou, X.C.2    Wang, H.3    Bassi, S.4    Carducci, M.A.5    Eisenberger, M.A.6    Antonarakis, E.S.7
  • 6
    • 36849067027 scopus 로고    scopus 로고
    • A Phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer
    • Kumar NB, Krischer JP, Allen K, Riccardi D, Besterman-Dahan K, Salup R, Kang L, Xu P and Pow-Sang J. A Phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer. Nutr Cancer. 2007; 59:163-168.
    • (2007) Nutr Cancer , vol.59 , pp. 163-168
    • Kumar, N.B.1    Krischer, J.P.2    Allen, K.3    Riccardi, D.4    Besterman-Dahan, K.5    Salup, R.6    Kang, L.7    Xu, P.8    Pow-Sang, J.9
  • 10
    • 84986322682 scopus 로고    scopus 로고
    • Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer
    • Das TP, Suman S, Alatassi H, Ankem MK and Damodaran C. Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer. Cell Death Dis. 2016; 7:e2111.
    • (2016) Cell Death Dis , vol.7 , pp. e2111
    • Das, T.P.1    Suman, S.2    Alatassi, H.3    Ankem, M.K.4    Damodaran, C.5
  • 11
    • 0037229714 scopus 로고    scopus 로고
    • Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells
    • Arboleda MJ, Lyons JF, Kabbinavar FF, Bray MR, Snow BE, Ayala R, Danino M, Karlan BY and Slamon DJ. Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells. Cancer research. 2003; 63:196-206.
    • (2003) Cancer research , vol.63 , pp. 196-206
    • Arboleda, M.J.1    Lyons, J.F.2    Kabbinavar, F.F.3    Bray, M.R.4    Snow, B.E.5    Ayala, R.6    Danino, M.7    Karlan, B.Y.8    Slamon, D.J.9
  • 13
    • 84865747484 scopus 로고    scopus 로고
    • Distinct roles of AKT isoforms in regulating beta1-integrin activity, migration, and invasion in prostate cancer
    • Virtakoivu R, Pellinen T, Rantala JK, Perala M and Ivaska J. Distinct roles of AKT isoforms in regulating beta1-integrin activity, migration, and invasion in prostate cancer. Molecular biology of the cell. 2012; 23:3357-3369.
    • (2012) Molecular biology of the cell , vol.23 , pp. 3357-3369
    • Virtakoivu, R.1    Pellinen, T.2    Rantala, J.K.3    Perala, M.4    Ivaska, J.5
  • 14
    • 0026021385 scopus 로고
    • The photolability of hydroxamic acids and its importance to the human environment
    • Lipczynska-Kochany E. The photolability of hydroxamic acids and its importance to the human environment. Sci Total Environ. 1991; 100 Spec No:469-482.
    • (1991) Sci Total Environ , vol.100 , pp. 469-482
    • Lipczynska-Kochany, E.1
  • 15
    • 0035369623 scopus 로고    scopus 로고
    • Transcriptiondependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway
    • Brunet A, Datta SR and Greenberg ME. Transcriptiondependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway. Current opinion in neurobiology. 2001; 11:297-305.
    • (2001) Current opinion in neurobiology , vol.11 , pp. 297-305
    • Brunet, A.1    Datta, S.R.2    Greenberg, M.E.3
  • 16
    • 61349137083 scopus 로고    scopus 로고
    • A new fork for clinical application: targeting forkhead transcription factors in cancer
    • Yang JY and Hung MC. A new fork for clinical application: targeting forkhead transcription factors in cancer. Clin Cancer Res. 2009; 15:752-757.
    • (2009) Clin Cancer Res , vol.15 , pp. 752-757
    • Yang, J.Y.1    Hung, M.C.2
  • 17
    • 84877745840 scopus 로고    scopus 로고
    • IKBKE phosphorylation and inhibition of FOXO3a: a mechanism of IKBKE oncogenic function
    • Guo JP, Tian W, Shu S, Xin Y, Shou C and Cheng JQ. IKBKE phosphorylation and inhibition of FOXO3a: a mechanism of IKBKE oncogenic function. PLoS One. 2013; 8:e63636.
    • (2013) PLoS One , vol.8
    • Guo, J.P.1    Tian, W.2    Shu, S.3    Xin, Y.4    Shou, C.5    Cheng, J.Q.6
  • 20
    • 0038244793 scopus 로고    scopus 로고
    • Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial
    • Duffield-Lillico AJ, Dalkin BL, Reid ME, Turnbull BW, Slate EH, Jacobs ET, Marshall JR, Clark LC and Nutritional Prevention of Cancer Study G. Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial. BJU Int. 2003; 91:608-612.
    • (2003) BJU Int , vol.91 , pp. 608-612
    • Duffield-Lillico, A.J.1    Dalkin, B.L.2    Reid, M.E.3    Turnbull, B.W.4    Slate, E.H.5    Jacobs, E.T.6    Marshall, J.R.7    Clark, L.C.8
  • 21
    • 0031418908 scopus 로고    scopus 로고
    • Antioxidant activity of glycowithanolides from Withania somnifera
    • Bhattacharya SK, Satyan KS and Ghosal S. Antioxidant activity of glycowithanolides from Withania somnifera. Indian J Exp Biol. 1997; 35:236-239.
    • (1997) Indian J Exp Biol , vol.35 , pp. 236-239
    • Bhattacharya, S.K.1    Satyan, K.S.2    Ghosal, S.3
  • 24
    • 84866052111 scopus 로고    scopus 로고
    • A novel MMP-2 inhibitor 3-azidowithaferin A (3-azidoWA) abrogates cancer cell invasion and angiogenesis by modulating extracellular Par- 4
    • Rah B, Amin H, Yousuf K, Khan S, Jamwal G, Mukherjee D and Goswami A. A novel MMP-2 inhibitor 3-azidowithaferin A (3-azidoWA) abrogates cancer cell invasion and angiogenesis by modulating extracellular Par- 4. PloS one. 2012; 7:e44039.
    • (2012) PloS one , vol.7
    • Rah, B.1    Amin, H.2    Yousuf, K.3    Khan, S.4    Jamwal, G.5    Mukherjee, D.6    Goswami, A.7
  • 25
    • 33846436451 scopus 로고    scopus 로고
    • Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells
    • Srinivasan S, Ranga RS, Burikhanov R, Han SS and Chendil D. Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells. Cancer Res. 2007; 67:246-253.
    • (2007) Cancer Res , vol.67 , pp. 246-253
    • Srinivasan, S.1    Ranga, R.S.2    Burikhanov, R.3    Han, S.S.4    Chendil, D.5
  • 26
    • 84944530017 scopus 로고    scopus 로고
    • Chemopreventive effect of Korean Angelica root extract on TRAMP carcinogenesis and integrative "omic" profiling of affected neuroendocrine carcinomas
    • Zhang J, Wang L, Zhang Y, Li L, Tang S, Xing C, Kim SH, Jiang C and Lu J. Chemopreventive effect of Korean Angelica root extract on TRAMP carcinogenesis and integrative "omic" profiling of affected neuroendocrine carcinomas. Mol Carcinog. 2015; 54:1567-1583.
    • (2015) Mol Carcinog , vol.54 , pp. 1567-1583
    • Zhang, J.1    Wang, L.2    Zhang, Y.3    Li, L.4    Tang, S.5    Xing, C.6    Kim, S.H.7    Jiang, C.8    Lu, J.9
  • 30
    • 2342625403 scopus 로고    scopus 로고
    • Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model
    • Gupta S, Adhami VM, Subbarayan M, MacLennan GT, Lewin JS, Hafeli UO, Fu P and Mukhtar H. Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2004; 64:3334-3343.
    • (2004) Cancer Res , vol.64 , pp. 3334-3343
    • Gupta, S.1    Adhami, V.M.2    Subbarayan, M.3    MacLennan, G.T.4    Lewin, J.S.5    Hafeli, U.O.6    Fu, P.7    Mukhtar, H.8
  • 32
    • 0034665334 scopus 로고    scopus 로고
    • Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice
    • Gupta S, Ahmad N, Marengo SR, MacLennan GT, Greenberg NM and Mukhtar H. Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice. Cancer Res. 2000; 60:5125-5133.
    • (2000) Cancer Res , vol.60 , pp. 5125-5133
    • Gupta, S.1    Ahmad, N.2    Marengo, S.R.3    MacLennan, G.T.4    Greenberg, N.M.5    Mukhtar, H.6
  • 33
    • 0035964175 scopus 로고    scopus 로고
    • Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols
    • Gupta S, Hastak K, Ahmad N, Lewin JS and Mukhtar H. Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proc Natl Acad Sci U S A. 2001; 98:10350-10355.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10350-10355
    • Gupta, S.1    Hastak, K.2    Ahmad, N.3    Lewin, J.S.4    Mukhtar, H.5
  • 34
    • 0036494569 scopus 로고    scopus 로고
    • Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model
    • Raghow S, Hooshdaran MZ, Katiyar S and Steiner MS. Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model. Cancer Res. 2002; 62:1370-1376.
    • (2002) Cancer Res , vol.62 , pp. 1370-1376
    • Raghow, S.1    Hooshdaran, M.Z.2    Katiyar, S.3    Steiner, M.S.4
  • 37
  • 38
    • 7244243792 scopus 로고    scopus 로고
    • Prostate carcinoma and green tea: (-)epigallocatechin-3-gallate inhibits inflammation-triggered MMP-2 activation and invasion in murine TRAMP model
    • Sartor L, Pezzato E, Dona M, Dell'Aica I, Calabrese F, Morini M, Albini A and Garbisa S. Prostate carcinoma and green tea: (-)epigallocatechin-3-gallate inhibits inflammation-triggered MMP-2 activation and invasion in murine TRAMP model. Int J Cancer. 2004; 112:823-829.
    • (2004) Int J Cancer , vol.112 , pp. 823-829
    • Sartor, L.1    Pezzato, E.2    Dona, M.3    Dell'Aica, I.4    Calabrese, F.5    Morini, M.6    Albini, A.7    Garbisa, S.8
  • 39
    • 9244263047 scopus 로고    scopus 로고
    • Oral consumption of green tea polyphenols inhibits insulin-like growth factor-I-induced signaling in an autochthonous mouse model of prostate cancer
    • Adhami VM, Siddiqui IA, Ahmad N, Gupta S and Mukhtar H. Oral consumption of green tea polyphenols inhibits insulin-like growth factor-I-induced signaling in an autochthonous mouse model of prostate cancer. Cancer Res. 2004; 64:8715-8722.
    • (2004) Cancer Res , vol.64 , pp. 8715-8722
    • Adhami, V.M.1    Siddiqui, I.A.2    Ahmad, N.3    Gupta, S.4    Mukhtar, H.5
  • 40
    • 33947626040 scopus 로고    scopus 로고
    • Genistein chemoprevention of prostate cancer in TRAMP mice
    • Wang J, Eltoum IE and Lamartiniere CA. Genistein chemoprevention of prostate cancer in TRAMP mice. J Carcinog. 2007; 6:3.
    • (2007) J Carcinog , vol.6 , pp. 3
    • Wang, J.1    Eltoum, I.E.2    Lamartiniere, C.A.3
  • 41
    • 0035884610 scopus 로고    scopus 로고
    • Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP)
    • Mentor-Marcel R, Lamartiniere CA, Eltoum IE, Greenberg NM and Elgavish A. Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP). Cancer Res. 2001; 61:6777-6782.
    • (2001) Cancer Res , vol.61 , pp. 6777-6782
    • Mentor-Marcel, R.1    Lamartiniere, C.A.2    Eltoum, I.E.3    Greenberg, N.M.4    Elgavish, A.5
  • 42
    • 84870326497 scopus 로고    scopus 로고
    • Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKCepsilon, Stat3 and neuroendocrine markers
    • Hafeez BB, Zhong W, Mustafa A, Fischer JW, Witkowsky O and Verma AK. Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKCepsilon, Stat3 and neuroendocrine markers. Carcinogenesis. 2012; 33:2586-2592.
    • (2012) Carcinogenesis , vol.33 , pp. 2586-2592
    • Hafeez, B.B.1    Zhong, W.2    Mustafa, A.3    Fischer, J.W.4    Witkowsky, O.5    Verma, A.K.6
  • 43
    • 84857949057 scopus 로고    scopus 로고
    • Oral infusion of pomegranate fruit extract inhibits prostate carcinogenesis in the TRAMP model
    • Adhami VM, Siddiqui IA, Syed DN, Lall RK and Mukhtar H. Oral infusion of pomegranate fruit extract inhibits prostate carcinogenesis in the TRAMP model. Carcinogenesis. 2012; 33:644-651.
    • (2012) Carcinogenesis , vol.33 , pp. 644-651
    • Adhami, V.M.1    Siddiqui, I.A.2    Syed, D.N.3    Lall, R.K.4    Mukhtar, H.5
  • 44
    • 22144449607 scopus 로고    scopus 로고
    • Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model
    • Shukla S, Maclennan GT, Marengo SR, Resnick MI and Gupta S. Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model. Prostate. 2005; 64:224-239.
    • (2005) Prostate , vol.64 , pp. 224-239
    • Shukla, S.1    Maclennan, G.T.2    Marengo, S.R.3    Resnick, M.I.4    Gupta, S.5
  • 45
    • 84861576558 scopus 로고    scopus 로고
    • Regulation of neuroendocrine differentiation by AKT/hnRNPK/AR/beta-catenin signaling in prostate cancer cells
    • Ciarlo M, Benelli R, Barbieri O, Minghelli S, Barboro P, Balbi C and Ferrari N. Regulation of neuroendocrine differentiation by AKT/hnRNPK/AR/beta-catenin signaling in prostate cancer cells. Int J Cancer. 2012; 131:582-590.
    • (2012) Int J Cancer , vol.131 , pp. 582-590
    • Ciarlo, M.1    Benelli, R.2    Barbieri, O.3    Minghelli, S.4    Barboro, P.5    Balbi, C.6    Ferrari, N.7
  • 50
    • 84920496306 scopus 로고    scopus 로고
    • Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells
    • Li X, Zhu F, Jiang J, Sun C, Wang X, Shen M, Tian R, Shi C, Xu M, Peng F, Guo X, Wang M and Qin R. Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells. Cancer Lett. 2015; 357:219-230.
    • (2015) Cancer Lett , vol.357 , pp. 219-230
    • Li, X.1    Zhu, F.2    Jiang, J.3    Sun, C.4    Wang, X.5    Shen, M.6    Tian, R.7    Shi, C.8    Xu, M.9    Peng, F.10    Guo, X.11    Wang, M.12    Qin, R.13
  • 51
    • 27644473229 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition
    • Radisky DC. Epithelial-mesenchymal transition. J Cell Sci. 2005; 118:4325-4326.
    • (2005) J Cell Sci , vol.118 , pp. 4325-4326
    • Radisky, D.C.1
  • 53
    • 84930010198 scopus 로고    scopus 로고
    • Over-expression of lipocalin 2 promotes cell migration and invasion through activating ERK signaling to increase SLUG expression in prostate cancer
    • Ding G, Fang J, Tong S, Qu L, Jiang H, Ding Q and Liu J. Over-expression of lipocalin 2 promotes cell migration and invasion through activating ERK signaling to increase SLUG expression in prostate cancer. Prostate. 2015; 75:957-968.
    • (2015) Prostate , vol.75 , pp. 957-968
    • Ding, G.1    Fang, J.2    Tong, S.3    Qu, L.4    Jiang, H.5    Ding, Q.6    Liu, J.7
  • 54
    • 84902535394 scopus 로고    scopus 로고
    • Induction of reactive oxygen species generation inhibits epithelial-mesenchymal transition and promotes growth arrest in prostate cancer cells
    • Das TP, Suman S and Damodaran C. Induction of reactive oxygen species generation inhibits epithelial-mesenchymal transition and promotes growth arrest in prostate cancer cells. Mol Carcinog. 2014; 53:537-547.
    • (2014) Mol Carcinog , vol.53 , pp. 537-547
    • Das, T.P.1    Suman, S.2    Damodaran, C.3
  • 57
    • 84927005883 scopus 로고    scopus 로고
    • Withaferin A inhibits experimental epithelial-mesenchymal transition in MCF-10A cells and suppresses vimentin protein level in vivo in breast tumors
    • Lee J, Hahm ER, Marcus AI and Singh SV. Withaferin A inhibits experimental epithelial-mesenchymal transition in MCF-10A cells and suppresses vimentin protein level in vivo in breast tumors. Mol Carcinog. 2015; 54:417-429.
    • (2015) Mol Carcinog , vol.54 , pp. 417-429
    • Lee, J.1    Hahm, E.R.2    Marcus, A.I.3    Singh, S.V.4
  • 58
    • 84859450097 scopus 로고    scopus 로고
    • Cancer stem cells and drug resistance: the potential of nanomedicine
    • Vinogradov S and Wei X. Cancer stem cells and drug resistance: the potential of nanomedicine. Nanomedicine (Lond). 2012; 7:597-615.
    • (2012) Nanomedicine (Lond) , vol.7 , pp. 597-615
    • Vinogradov, S.1    Wei, X.2
  • 59
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T and Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer. 2005; 5:275-284.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3


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